Mapping Genes To Cardiovascular Susceptibility Loci At A Single-Cell Resolution

Autor: Van Der Laan, S.W., Slenders, L., Depuydt, M., Prange, K., Granneman, L., Elbersen, D., Boltjes, A., de Jager, S., Slütter, B., Bot, I., Winther, M., Kuiper, J., Mokry, M., Asselbergs, F., Pasterkamp, G.

Publikováno v: In Atherosclerosis August 2019 287:e21-e21

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.

Autor: Depuydt MAC; Leiden Academic Centre for Drug Research, Division of Biotherapeutics, Leiden University, Einsteinweg 55, Leiden, the Netherlands (M.A.C.D., I.B., B.S., J.K.)., Prange KHM; Amsterdam University Medical Centers-Location AMC, University of Amsterdam, Experimental Vascular Biology, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Meibergdreef 9, the Netherlands (K.H.M.P., M.P.J.d.W.)., Slenders L; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.)., Örd T; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland (T.O., E.A., M.U.K., S.Y.-H.)., Elbersen D; Laboratory for Experimental Cardiology (D.E., S.C.A.d.J), University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Boltjes A; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.)., de Jager SCA; Laboratory for Experimental Cardiology (D.E., S.C.A.d.J), University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Asselbergs FW; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.)., de Borst GJ; Vascular Surgery (G.J.d.B.), University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Aavik E; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland (T.O., E.A., M.U.K., S.Y.-H.)., Lönnberg T; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Finland (T.L.)., Lutgens E; Institute for Cardiovascular Prevention (IPEK), Munich, Germany (E.L., M.P.J.d.W.).; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany (E.L., M.P.J.d.W.)., Glass CK; Cell and Molecular Medicine (C.K.G.), University of California San Diego, CA.; School of Medicine (C.K.G.), University of California San Diego, CA., den Ruijter HM; Cardiology (H.M.d.R., M.M.), University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Kaikkonen MU; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland (T.O., E.A., M.U.K., S.Y.-H.)., Bot I; Leiden Academic Centre for Drug Research, Division of Biotherapeutics, Leiden University, Einsteinweg 55, Leiden, the Netherlands (M.A.C.D., I.B., B.S., J.K.)., Slütter B; Leiden Academic Centre for Drug Research, Division of Biotherapeutics, Leiden University, Einsteinweg 55, Leiden, the Netherlands (M.A.C.D., I.B., B.S., J.K.)., van der Laan SW; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.)., Yla-Herttuala S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland (T.O., E.A., M.U.K., S.Y.-H.)., Mokry M; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.).; Cardiology (H.M.d.R., M.M.), University Medical Center Utrecht, Heidelberglaan 100, the Netherlands., Kuiper J; Leiden Academic Centre for Drug Research, Division of Biotherapeutics, Leiden University, Einsteinweg 55, Leiden, the Netherlands (M.A.C.D., I.B., B.S., J.K.)., de Winther MPJ; Amsterdam University Medical Centers-Location AMC, University of Amsterdam, Experimental Vascular Biology, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Meibergdreef 9, the Netherlands (K.H.M.P., M.P.J.d.W.).; Institute for Cardiovascular Prevention (IPEK), Munich, Germany (E.L., M.P.J.d.W.).; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany (E.L., M.P.J.d.W.)., Pasterkamp G; Laboratory of Clinical Chemistry and Haematology, University Medical Center, Heidelberglaan 100, Utrecht, the Netherlands (L.S., A.B., F.W.A., S.W.v.d.L., M.M., G.P.).

Publikováno v: Circulation research [Circ Res] 2020 Nov 06; Vol. 127 (11), pp. 1437-1455. Date of Electronic Publication: 2020 Sep 28.

Intense impact of IL-1β expressing inflammatory macrophages in acute aortic dissection.

Autor: Inoue, Taishi¹ (AUTHOR), Emoto, Takuo² (AUTHOR), Yamanaka, Katsuhiro¹ (AUTHOR), Chomei, Shunya¹ (AUTHOR), Miyahara, Shunsuke¹ (AUTHOR), Takahashi, Hiroaki¹ (AUTHOR), Shinohara, Ryohei² (AUTHOR), Kondo, Takeshi³ (AUTHOR), Taniguchi, Masayuki⁴ (AUTHOR), Furuyashiki, Tomoyuki⁴ (AUTHOR), Yamashita, Tomoya⁵ (AUTHOR), Hirata, Ken-ichi² (AUTHOR), Okada, Kenji¹ (AUTHOR) kokada@med.kobe-u.ac.jp

Publikováno v: Scientific Reports. 6/27/2024, Vol. 14 Issue 1, p1-12. 12p.

Single Cell High Dimensional Analysis of Human Peripheral Blood Mononuclear Cells Reveals Unique Intermediate Monocyte Subsets Associated with Sex Differences in Coronary Artery Disease.

Autor: Chatterjee, Nandini¹ (AUTHOR) nchatterjee@lji.org, Komaravolu, Ravi K.² (AUTHOR) rkomaravolu@augusta.edu, Durant, Christopher P.¹ (AUTHOR) kley@augusta.edu, Wu, Runpei¹ (AUTHOR), McSkimming, Chantel³ (AUTHOR) amt6b@uvahealth.org, Drago, Fabrizio³ (AUTHOR), Kumar, Sunil² (AUTHOR), Valentin-Guillama, Gabriel² (AUTHOR), Miller, Yury I.⁴ (AUTHOR), McNamara, Coleen A.³ (AUTHOR), Ley, Klaus^1,2 (AUTHOR), Taylor, Angela³ (AUTHOR), Alimadadi, Ahmad^1,2 (AUTHOR) aalimadadi@augusta.edu, Hedrick, Catherine C.^1,2 (AUTHOR) aalimadadi@augusta.edu

Publikováno v: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2894. 21p.

Emerging applications of single-cell profiling in precision medicine of atherosclerosis.

Autor: Lin, Huiling^1,2 (AUTHOR), Zhang, Ming³ (AUTHOR), Hu, Mi¹ (AUTHOR), Zhang, Yangkai¹ (AUTHOR), Jiang, WeiWei⁴ (AUTHOR), Tang, Wanying¹ (AUTHOR), Ouyang, Yuxin¹ (AUTHOR), Jiang, Liping⁵ (AUTHOR), Mi, Yali³ (AUTHOR), Chen, Zhi⁶ (AUTHOR), He, Pingping⁷ (AUTHOR) hpp-612@163.com, Zhao, Guojun³ (AUTHOR) zhaoguojun@gzhmu.edu.cn, Ouyang, Xinping^1,2,8,9 (AUTHOR) y1655@163.com

Publikováno v: Journal of Translational Medicine. 1/23/2024, Vol. 22 Issue 1, p1-14. 14p.