Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Elbahnsi, A."'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2548-2564 (2024)
P-glycoprotein (P-gp) plays a crucial role in cellular detoxification and drug efflux processes, transitioning between inward-facing (IF) open, occluded, and outward-facing (OF) states to facilitate substrate transport. Its role is critical in cancer
Externí odkaz:
https://doaj.org/article/a89cc4aff34b495182c4b60c28beb7de
Autor:
Kevin Uguen, Marlène Le Tertre, Dimitri Tchernitchko, Ahmad Elbahnsi, Sandrine Maestri, Isabelle Gourlaouen, Claude Férec, Chandran Ka, Isabelle Callebaut, Gérald Le Gac
Publikováno v:
HGG Advances, Vol 5, Iss 4, Pp 100335- (2024)
Summary: Heterozygous mutations in SLC40A1, encoding a multi-pass membrane protein of the major facilitator superfamily known as ferroportin 1 (FPN1), are responsible for two distinct hereditary iron-overload diseases: ferroportin disease, which is a
Externí odkaz:
https://doaj.org/article/628bcda8ead241819061e4af36cf09ea
Autor:
Uguen, Kevin, Le Tertre, Marlène, Tchernitchko, Dimitri, Elbahnsi, Ahmad, Maestri, Sandrine, Gourlaouen, Isabelle, Férec, Claude, Ka, Chandran, Callebaut, Isabelle, Le Gac, Gérald
Publikováno v:
In Human Genetics and Genomics Advances 10 October 2024 5(4)
Publikováno v:
In Computational and Structural Biotechnology Journal December 2024 23:2548-2564
Akademický článek
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Akademický článek
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Autor:
Ahmad Elbahnsi, John Cowgill, Verena Burtscher, Linda Wedemann, Luise Zeckey, Baron Chanda, Lucie Delemotte
Publikováno v:
eLife, Vol 12 (2023)
Hyperpolarized-activated and cyclic nucleotide-gated (HCN) channels are the only members of the voltage-gated ion channel superfamily in mammals that open upon hyperpolarization, conferring them pacemaker properties that are instrumental for rhythmic
Externí odkaz:
https://doaj.org/article/a778ab82133345d6a0097b0f26ea1a96
Autor:
Mehregan, Aujan, Pérez-Conesa, Sergio, Zhuang, Yuxuan, Elbahnsi, Ahmad, Pasini, Diletta, Lindahl, Erik, Howard, Rebecca J., Ulens, Chris, Delemotte, Lucie
Publikováno v:
In BBA - Biomembranes 1 October 2022 1864(10)
Autor:
Sara Bitam, Ahmad Elbahnsi, Geordie Creste, Iwona Pranke, Benoit Chevalier, Farouk Berhal, Brice Hoffmann, Nathalie Servel, Danielle Tondelier, Aurelie Hatton, Christelle Moquereau, Mélanie Faria Da Cunha, Alexandra Pastor, Agathe Lepissier, Alexandre Hinzpeter, Jean-Paul Mornon, Guillaume Prestat, Aleksander Edelman, Isabelle Callebaut, Christine Gravier-Pelletier, Isabelle Sermet-Gaudelus
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract C407 is a compound that corrects the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein carrying the p.Phe508del (F508del) mutation. We investigated the corrector effect of c407 and its derivatives on F508del-CFTR protein. Mo
Externí odkaz:
https://doaj.org/article/c78c19594a5d4a81b0e0face0bb082c4
Autor:
Froux, Lionel, Elbahnsi, Ahmad, Boucherle, Benjamin, Billet, Arnaud, Baatallah, Nesrine, Hoffmann, Brice, Alliot, Julien, Zelli, Renaud, Zeinyeh, Wael, Haudecoeur, Romain, Chevalier, Benoit, Fortuné, Antoine, Mirval, Sandra, Simard, Christophe, Lehn, Pierre, Mornon, Jean-Paul, Hinzpeter, Alexandre, Becq, Frédéric, Callebaut, Isabelle, Décout, Jean-Luc
Publikováno v:
In European Journal of Medicinal Chemistry 15 March 2020 190