Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Elba M. Hadden"'
Autor:
Jose Luis Barrera, Emma Verastegui, J de la Garza, Elba M. Hadden, Abelardo Meneses, Juan Zinser, John W. Hadden, M Kurman
Publikováno v:
International Immunopharmacology. 3:1073-1081
A Phase II trial in 42 patients with squamous cell cancer of the head and neck (H and NSCC) was performed using a combination immunotherapy with 10-20 days of perilymphatic injections of a natural cytokine mixture (NCM: IRX-2; 200 units IL-2 equivale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4623fccc6e2dc4428c7da8db590ff873
https://doi.org/10.1016/s1567-5769(03)00029-8
https://doi.org/10.1016/s1567-5769(03)00029-8
Autor:
Ronald G. Coffey, Alfredo Giner-Sorolla, Marina Sosa, John W. Hadden, Yulai Wang, Elba M. Hadden
Publikováno v:
International Journal of Immunopharmacology. 17:763-770
Methyl inosine monophosphate (MIMP) augments preferentially the in vitro responses of human and murine lymphocytes to a T-cell mitogen such as phytohemagglutinin (PHA) and inconsistently to a B-cell mitogen such as pokeweed or lipopolysaccharide (LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264baf53c127afa0f52774513f16cab4
https://doi.org/10.1016/0192-0561(95)00065-a
https://doi.org/10.1016/0192-0561(95)00065-a
Publikováno v:
Annals of the New York Academy of Sciences. 685:458-463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e59f5d08294d7bccb3cad00aa4c9a0
https://doi.org/10.1111/j.1749-6632.1993.tb35906.x
https://doi.org/10.1111/j.1749-6632.1993.tb35906.x
Autor:
Anutosh R. Saha, John W. Hadden, Elba M. Hadden, Marina Sosa, Yulai Wang, Alfredo Giner-Sorolla, Jorge Coto
Publikováno v:
International Journal of Immunopharmacology. 14:1259-1266
Inosine 5′ - methyl monophosphate (MIMP) is a new immunomodulator designed to improve upon the activity of other thymomimetic purines. In Balb/c mice, MIMP was assessed for toxicity and activity on immune responses. The lethal dose for half the mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d3e87323bc73c27799cca4169216ca
https://doi.org/10.1016/0192-0561(92)90062-p
https://doi.org/10.1016/0192-0561(92)90062-p
Autor:
Robert M. Nelson, Alfredo Giner-Sorolla, Elba M. Hadden, Craig Monell, Steven Specter, John W. Hadden, Joseph Ongradi, Mette Strand, Marina Sosa
Publikováno v:
International Journal of Immunopharmacology. 14:555-563
MIMP is a new thymomimetic purine under development for immunorestorative therapy. Lymphocytes were obtained from eight patients with acquired immunodeficiency disease (AIDS), eight with symptomatic pre-AIDS (ARC), and 22 normal controls and were sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36f449636b94564f125f8f8e50e48af
https://doi.org/10.1016/0192-0561(92)90116-3
https://doi.org/10.1016/0192-0561(92)90116-3
Publikováno v:
International Journal of Immunopharmacology. 13:49-54
Prior work has documented the thymomimetic and immunotherapeutic activity of purine molecules related in structure to inosine. Synthesis of a series of new structures has yielded a stable methylated form of IMP resistant to hydrolysis by 5′ nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02f7f77c3458e8266169f6ac2609ac9
https://doi.org/10.1016/0192-0561(91)90124-p
https://doi.org/10.1016/0192-0561(91)90124-p
Autor:
Nancy E. Zorn, Paul D. Crowe, Arthur R. Buckley, Hugh E. Laird, Diane Haddock Russell, Robert V. Farese, Elba M. Hadden, Marie D. Sauro
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 188:139-152
Prolactin (PRL) and other trophic factors rapidly activate a nuclear pool(s) of protein kinase C (nPKC) in purified splenocyte nuclei. The PRL also enhanced [2-3H]glycerol incorporation into nuclear mono- and triacylglycerol. An assay was devised whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0618d146324d784c59a307663cbbdfcf
https://doi.org/10.1016/0922-4106(90)90049-4
https://doi.org/10.1016/0922-4106(90)90049-4
Publikováno v:
Annals of the New York Academy of Sciences. 1112
Mouse studies showed a synergy of thymosin alpha1 (Talpha1) and a natural cytokine mixture (IRX-2) in increasing T lymphocyte number and responses. Clinical studies with IRX-2 showed increases of T lymphocytes in lymphocytopenic cancer patients but r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd15c6f11e12ea5b92ba3b59f3a47d2a
https://pubmed.ncbi.nlm.nih.gov/17600288
https://pubmed.ncbi.nlm.nih.gov/17600288
Publikováno v:
International journal of immunopharmacology. 17(10)
Cytokines and thymic hormones are thought to play critical roles in the regulation of T-lymphocyte development and function. In an effort to determine the effectiveness of such agents in an immunotherapeutic strategy, we employed aged mice in a hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab180de1f03f8d1f5cdfb72046019b0b
https://pubmed.ncbi.nlm.nih.gov/8707447
https://pubmed.ncbi.nlm.nih.gov/8707447
Publikováno v:
International journal of immunopharmacology. 17(9)
Zinc is incorporated into zinc-thymulin by the thymus and in this form is a critical hormonal regulator of cellular immunity. In the absence of serum, zinc induces human thymic epithelial cells (TEC) to secrete a factor which promotes the expansion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408c6656b3241990b19dbd2b7a8ea9d1
https://pubmed.ncbi.nlm.nih.gov/8582784
https://pubmed.ncbi.nlm.nih.gov/8582784