Acute Stress Regulates Sex-Related Molecular Responses in the Human Jejunal Mucosa: Implications for Irritable Bowel Syndrome

Autor: Bruno K. Rodiño-Janeiro, Marc Pigrau, Eloísa Salvo-Romero, Adoración Nieto, Elba Expósito, Ana M. González-Castro, Carmen Galán, Inés de Torres, Teodora Pribic, Laura Hernández, Beatriz Lobo, Marina Fortea, Milagros Gallart, Cristina Pardo-Camacho, Danila Guagnozzi, Javier Santos, Carmen Alonso-Cotoner

Publikováno v: Cells, Vol 12, Iss 3, p 423 (2023)

Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder linked to intestinal barrier dysfunction and life stress. We have previously reported that female sex per se determines an increased susceptibility to intestinal barrier dysfunct

Externí odkaz: https://doaj.org/article/fc20ee996c774f7297c7fdf69a8958bf

Mucosal Plasma Cell Activation and Proximity to Nerve Fibres Are Associated with Glycocalyx Reduction in Diarrhoea-Predominant Irritable Bowel Syndrome: Jejunal Barrier Alterations Underlying Clinical Manifestations

Autor: Cristina Pardo-Camacho, John-Peter Ganda Mall, Cristina Martínez, Marc Pigrau, Elba Expósito, Mercé Albert-Bayo, Elisa Melón-Ardanaz, Adoración Nieto, Bruno Rodiño-Janeiro, Marina Fortea, Danila Guagnozzi, Amanda Rodriguez-Urrutia, Inés de Torres, Ignacio Santos-Briones, Fernando Azpiroz, Beatriz Lobo, Carmen Alonso-Cotoner, Javier Santos, Ana M. González-Castro, Maria Vicario

Publikováno v: Cells, Vol 11, Iss 13, p 2046 (2022)

Irritable bowel syndrome (IBS) is a disorder of brain-gut interaction characterised by abdominal pain and changes in bowel habits. In the diarrhoea subtype (IBS-D), altered epithelial barrier and mucosal immune activation are associated with clinical

Externí odkaz: https://doaj.org/article/2ac9667546bf417d84e523b320cfeee2

The Role of Purported Mucoprotectants in Dealing with Irritable Bowel Syndrome, Functional Diarrhea, and Other Chronic Diarrheal Disorders in Adults

Autor: Mercé Albert-Bayo, Ana M González-Castro, Javier Santos, Beatriz Lobo, Carmen Alonso-Cotoner, Elba Expósito, John-P Ganda Mall, Mar Abril-Gil

Publikováno v: Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Advances in Therapy

Chronic diarrhea is a frequent presenting symptom, both in primary care medicine and in specialized gastroenterology units. It is estimated that more than 5% of the global population suffers from chronic diarrhea. and that about 40% of these subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ea1f7d214c49f60f10250144219f65
https://ddd.uab.cat/record/238778

Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite

Autor: Elba Expósito, Jesús Ruiz-Cabello, Amanda Sánchez-López, Manuel Desco, Gabriela Guzmán-Martínez, Richard K. Assoian, Lorena Cussó, Mercedes Salaices, Ana M. Briones, Lara del Campo, Ryan A. von Kleeck, Vicente Andrés, Cristina González-Gómez

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Aging Cell

Vascular stiffness is a major cause of cardiovascular disease during normal aging and in Hutchinson–Gilford progeria syndrome (HGPS), a rare genetic disorder caused by ubiquitous progerin expression. This mutant form of lamin A causes premature agi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67079faaebdce6e3b56c46cd7f9a823b
http://hdl.handle.net/20.500.12105/7720