Zobrazeno 1 - 10
of 568
pro vyhledávání: '"Elazer R Edelman"'
Autor:
Jonathan Kusner, Giulia Luraghi, Farhan Khodaee, José Félix Rodriguez Matas, Francesco Migliavacca, Elazer R Edelman, Farhad R Nezami
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251579 (2021)
The bicuspid aortic valve (BAV) is a common and heterogeneous congenital heart abnormality that is often complicated by aortic stenosis. Although initially developed for tricuspid aortic valves (TAV), transcatheter aortic valve replacement (TAVR) dev
Externí odkaz:
https://doaj.org/article/e1430077fdeb4b6dbe8db8d48cdc7be2
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Numerical simulations of cardiovascular device deployment within digital twins of patient-specific anatomy can expedite and de-risk the device design process. Nonetheless, the exclusive use of patient-specific data constrains the anatomic va
Externí odkaz:
https://doaj.org/article/45406a9aa3954b68b4001e8a48dc16a6
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0192004 (2018)
Sex-related differences have been noted in cardiovascular anatomy, pathophysiology, and treatment responses, yet we continued to drive evaluation of vascular device development in animal models without consideration of animal sex. We aimed to underst
Externí odkaz:
https://doaj.org/article/f9209bb9fc5445ddaaf403ecc1d8faa9
Autor:
Brooke A. Krbec, Xiang Zhang, Inbar Chityat, Alexandria Brady-Mine, Evan Linton, Daniel Copeland, Brian W. Anthony, Elazer R. Edelman, Jonathan M. Davis
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Continuous monitoring of high-risk neonates is essential for the timely management of medical conditions. However, the current reliance on wearable or contact sensor technologies for vital sign monitoring often leads to complications including discom
Externí odkaz:
https://doaj.org/article/6defd29bab5a41998d7aa65354527201
Autor:
Caroline C O'Brien, Kumaran Kolandaivelu, Jonathan Brown, Augusto C Lopes, Mie Kunio, Vijaya B Kolachalama, Elazer R Edelman
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149178 (2016)
BACKGROUND:Stacking cross-sectional intravascular images permits three-dimensional rendering of endovascular implants, yet introduces between-frame uncertainties that limit characterization of device placement and the hemodynamic microenvironment. In
Externí odkaz:
https://doaj.org/article/3e3c3b9bb3914b6194de6297681e8455
Autor:
Pujith R S Vijayaratnam, Caroline C O'Brien, John A Reizes, Tracie J Barber, Elazer R Edelman
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128178 (2015)
Background and methodsIt is important to ensure that blood flow is modelled accurately in numerical studies of arteries featuring drug-eluting stents due to the significant proportion of drug transport from the stent into the arterial wall which is f
Externí odkaz:
https://doaj.org/article/a86e4f491b4e4634b248c77ac68a8e33
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8930 (2010)
Biological processes from embryogenesis to tumorigenesis rely on the coordinated coalescence of cells and synchronized cell-to-cell communication. Intercellular signaling enables cell masses to communicate through endocrine pathways at a distance or
Externí odkaz:
https://doaj.org/article/cef0d047f56b4270848945c4524c42ed
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8105 (2009)
Treatment of arterial bifurcation lesions using drug-eluting stents (DES) is now common clinical practice and yet the mechanisms governing drug distribution in these complex morphologies are incompletely understood. It is still not evident how to eff
Externí odkaz:
https://doaj.org/article/62fd554caa5548cf9e1729c07c8c97ee
Autor:
Leslie B. Gordon, Sammy Basso, Justine Maestranzi, Elena Aikawa, Cassandra L. Clift, Antonio Giovanni Cammardella, Tommaso Hinna Danesi, Pedro J. del Nido, Elazer R. Edelman, Abeer Hamdy, Sheila M. Hegde, Monica E. Kleinman, Nicola Maschietto, Mandeep R. Mehra, Srinivasan Mukundan, Francesco Musumeci, Marco Russo, Frank J. Rybicki, Pinak Bipin Shah, William A. Suarez, Kelsey Tuminelli, Katherine Zaleski, Ashwin Prakash, Marie Gerhard-Herman
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare genetic premature aging disease that is historically fatal in teenage years, secondary to severe accelerated atherosclerosis. The only approved treatment is the farnesyltransferase inhibito
Externí odkaz:
https://doaj.org/article/c233db4a024145d3811d09fb96c52220
Autor:
Mireia Medrano-Bosch, Blanca Simón-Codina, Wladimiro Jiménez, Elazer R. Edelman, Pedro Melgar-Lesmes
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate inflammation, angiogenesis, or tissue remodeling. Monocytes
Externí odkaz:
https://doaj.org/article/6c10c569e8344db7aa85ca734e82f9f4