Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elazar, Besser"'
Publikováno v:
eLife, Vol 12 (2024)
In T-cell acute lymphoblastic leukemia (T-ALL), more than 50% of cases display autoactivation of Notch1 signaling, leading to oncogenic transformation. We have previously identified a specific chemovar of Cannabis that induces apoptosis by preventing
Externí odkaz:
https://doaj.org/article/992a7a0a20fe47ebbdecbe6108e0dd96
Autor:
Elazar Besser, Anat Gelfand, Gil Moshe Lewitus, Hila Novak‐Kotzer, Shiri Procaccia, Paula Berman, Igal Louria‐Hayon, Inbar Shreiber‐Livne, Yishai Ofran, David Meiri
Publikováno v:
Cancer Communications, Vol 43, Iss 6, Pp 711-715 (2023)
Externí odkaz:
https://doaj.org/article/1a3ff57b52e44333a85c3b92ab490c20
Autor:
Kifah Blal, Elazar Besser, Shiri Procaccia, Ouri Schwob, Yaniv Lerenthal, Jawad Abu Tair, David Meiri, Ofra Benny
Publikováno v:
Cancers; Volume 15; Issue 2; Pages: 497
Cannabis sativa plants have a wide diversity in their metabolite composition among their different chemovars, facilitating diverse anti-tumoral effects on cancer cells. This research examined the anti-tumoral effects of 24 cannabis extracts represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59020eb0b68e0979db01016d07e9af52
Autor:
Kifah Blal, Elazar Besser, Shiri Procaccia, Ouri Schwob, Yaniv Lerenthal, Jawad Abu Tair, David Meiri, Ofra Benny
Publikováno v:
Cancers. 15:2481
In the original publication [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f7ab779e41043acd146e6ed4c07034
https://doi.org/10.3390/cancers15092481
https://doi.org/10.3390/cancers15092481
Autor:
Dzmitry Mukha, Mariam Fokra, Alona Feldman, Boris Sarvin, Nikita Sarvin, Keren Nevo-Dinur, Elazar Besser, Elior Hallo, Elina Aizenshtein, Zachary T. Schug, Tomer Shlomi
Publikováno v:
Cell Metab
The folic acid cycle mediates the transfer of one-carbon (1C) units to support nucleotide biosynthesis. While the importance of serine as a mitochondrial and cytosolic donor of folate-mediated 1C units in cancer cells has been thoroughly investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e6106efeea8b2afa74a0158e1a5979
https://europepmc.org/articles/PMC9583459/
https://europepmc.org/articles/PMC9583459/
Autor:
Ella Peled, Elazar Besser, Paula Berman, Liran Baram, Gil M. Lewitus, Igal Louria-Hayon, Ben Yellin, David Meiri, Maya Benami
Publikováno v:
Oncotarget. 10:4091-4106
The Cannabis plant contains over 100 phytocannabinoids and hundreds of other components. The biological effects and interplay of these Cannabis compounds are not fully understood and yet influence the plant's therapeutic effects. Here we assessed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c746237bfb185531691c70468aa3d067
https://doi.org/10.18632/oncotarget.26983
https://doi.org/10.18632/oncotarget.26983
Autor:
Nikita Sarvin, Shachar Raz, Shoval Lagziel, Elina Aizenshtein, Won Dong Lee, Dzmitry Mukha, Keren Nevo-Dinur, Tomer Shlomi, Anna Chiara Pirona, Elazar Besser, Boris Sarvin, Alon Stern
Publikováno v:
Cell metabolism. 33(1)
Summary Folate metabolism supplies one-carbon (1C) units for biosynthesis and methylation and has long been a target for cancer chemotherapy. Mitochondrial serine catabolism is considered the sole contributor of folate-mediated 1C units in proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5e44880c3aa51864c0fa100b8dc642
https://pubmed.ncbi.nlm.nih.gov/33326752
https://pubmed.ncbi.nlm.nih.gov/33326752
Autor:
Liran, Baram, Ella, Peled, Paula, Berman, Ben, Yellin, Elazar, Besser, Maya, Benami, Igal, Louria-Hayon, Gil M, Lewitus, David, Meiri
Publikováno v:
Oncotarget
The Cannabis plant contains over 100 phytocannabinoids and hundreds of other components. The biological effects and interplay of these Cannabis compounds are not fully understood and yet influence the plant’s therapeutic effects. Here we assessed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::346b4c4d2b6fe21b3e474038bcd0505a
https://pubmed.ncbi.nlm.nih.gov/31289609
https://pubmed.ncbi.nlm.nih.gov/31289609
Autor:
Rami I. Aqeilan, Sahar Sweetat, Oded Behar, Elazar Besser, Nechama Kronenberg, Saleh Khawaled, Liat Peretz, Liat Ben Gigi, Dan Ziv, Renana Hajbi, Natania Casden
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Inhibition of genes is a powerful approach to study their function. While RNA interference is a widely used method to achieve this goal, mounting evidence indicates that such an approach is prone to off-target effects. An alternative approach to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275d1a934f02dbbec6651de2ebba2729
https://doi.org/10.1038/s41598-017-18551-z
https://doi.org/10.1038/s41598-017-18551-z
Publikováno v:
European Journal of Cell Biology. 94:453-457
The biological activity of a recombinant protein is routinely measured using a bioassay such as an enzyme assay. However, many proteins have no enzymatic activity and in many cases it is difficult to devise a simple and reliable approach to test thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa1268d33fd71255de82a84b1f25823
https://doi.org/10.1016/j.ejcb.2015.06.006
https://doi.org/10.1016/j.ejcb.2015.06.006