Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Elastic fiber assembly"'
Publikováno v:
Tissue Eng Part A
Elastic fibers do not naturally regenerate in many proteolytic disorders, such as in abdominal aortic aneurysms, and prevent restoration of tissue homeostasis. We have shown drug-based attenuation of the stress-activated protein kinase, JNK-2 to stim
Publikováno v:
Clinical Genetics. 99:53-66
Cutis laxa (CL) syndromes comprise a rare group of multisystem disorders that share loose redundant skin folds as hallmark clinical feature. CL results from impaired elastic fiber assembly and homeostasis, and the known underlying gene defects affect
Publikováno v:
Experimental and Therapeutic Medicine
Long non-coding RNAs (lncRNAs) serve a crucial role in every aspect of cell biological functions as well as in a variety of diseases, including cardiovascular disease, cancer and nervous system disease. However, the differential expression profiles o
Publikováno v:
International Journal of Sports Physiology and Performance. 15:489-495
Purpose: The authors investigated the association between risk of tendinopathies and genetic markers in professional team sports. Methods: The authors studied 363 (mean [SD]; 25 [6] y, 89% male) elite players (soccer, futsal, basketball, handball, an
Publikováno v:
Journal of tissue engineering and regenerative medicineREFERENCES. 16(2)
Limitations of current treatments for auricular cartilage defects have prompted the field of auricular cartilage tissue engineering. To date, inducing the formation of cartilaginous constructs with biochemical and biomechanical properties of native t
Autor:
Kosei Fujita, Yasuyo Mikami, Samir Mitragotri, Kiyoshi Ikeda, Tadanobu Takahashi, Akira Minami, Ayano Iuchi, Mako Shiratori, Jun Goto, Ami Ishii, Yuuki Kurebayashi, Hiroaki Kanazawa, Yasunori Iwao, Tadamune Otsubo, Yuka Fujita, Takashi Suzuki
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Reduction of elastin in the skin causes various skin diseases as well as wrinkles and sagging with aging. Sialidase is a hydrolase that cleaves a sialic acid residue from sialoglycoconjugate. Cleavage of sialic acid from microfibrils by the sialidase
Autor:
Kalsang Dolma, Riet van der Meer, Matthew Xin, J. Edwin Blalock, Seunghyi Kook, Wei Han, Shivangi Dave, John T. Benjamin, Jonathan A. Kropski, David S. Nichols, Peter C. Dinella, Susan H. Guttentag, Erin J. Plosa, Christopher S. Jetter, Timothy S. Blackwell, Jennifer M.S. Sucre, Amit Gaggar, Lisa R. Young, Charitharth Vivek Lal, Ashley Catanzarite, Sergey Gutor, Peter Gulleman, Dawn C. Newcomb, Bradley W. Richmond
Publikováno v:
J Clin Invest
Emerging evidence indicates that early life events can increase the risk for developing chronic obstructive pulmonary disease (COPD). Using an inducible transgenic mouse model for NF-κB activation in the airway epithelium, we found that a brief peri
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030806132
Cutis laxa (CL) syndromes are a large and heterogeneous group of rare connective tissue disorders that share loose redundant skin as a hallmark clinical feature, which reflects dermal elastic fiber fragmentation. Both acquired and congenital-Mendelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10e2ad2c576e60a5071ef42e153c373
https://doi.org/10.1007/978-3-030-80614-9_13
https://doi.org/10.1007/978-3-030-80614-9_13
Publikováno v:
Journal of materials chemistry. B. 8(40)
Elastogenesis is a complex process beginning with transcription, translation, and extracellular release of precursor proteins leading to crosslinking, deposition, and assembly of ubiquitous elastic fibers. While the biochemical pathways by which elas
Autor:
Masahiro Akishita, Hironobu Hamaya, Sumito Ogawa, Yasuhiro Yamaguchi, Masaki Ishii, Yuko Iwata
Publikováno v:
Airway cell biology and immunopathology.
Latent TGF-β binding protein 4 is an important factor that influences anti-inflammatory and cell-protective responses in the pathogenesis of pulmonary empysema Rationale: Deficiency of the extracellular matrix protein latent transforming growth fact