Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elana Miriami"'
Autor:
Hugo Y. K. Lam, Hua Tang, Suganthi Balasubramanian, Jennifer Li-Pook-Than, Elana Miriami, Alan P. Boyle, Lukas Habegger, Euan A. Ashley, Keith Bettinger, Michael Snyder, Atul J. Butte, Kari C. Nadeau, Phyllis Snyder, Lihua Jiang, Teri E. Klein, Sara Hillenmeyer, Michelle Whirl-Carrillo, Frederick E. Dewey, Maeve O'Huallachain, Joel T. Dudley, Hogune Im, Konrad J. Karczewski, Scott Seki, Fabian Grubert, Mercedes Gallardo, Donald Sharon, Marco Garcia, Mark Gerstein, Manoj Hariharan, Maria A. Blasco, Russ B. Altman, Ghia Euskirchen, Peter L. Greenberg, Yong Cheng, Rui Chen, Michael J. Clark, Phil Lacroute, Rong Chen, George I. Mias, Maya Kasowski, Rajini R Haraksingh
Publikováno v:
Cell; Vol 148
SummaryPersonalized medicine is expected to benefit from combining genomic information with regular monitoring of physiological states by multiple high-throughput methods. Here, we present an integrative personal omics profile (iPOP), an analysis tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbde44ea58693d99019af4e77e4d243
Autor:
Shaun D. Roman, R. John Aitken, Ceanne A Wallace, Elana Miriami, Rebecca S Scott, Benjamin J. Curry
Publikováno v:
Genomics. 83:425-438
Cytochrome b5/cytochrome b5 reductase (cb5/cb5r) is a cytosolic fusion protein between the hemoprotein cytochrome b5 and the flavoprotein cytochrome b5 reductase. We describe the identification and characterization of a novel splice variant of cb5/cb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dcdca68b62e422df33c7001245bd74
https://doi.org/10.1016/j.ygeno.2003.08.020
https://doi.org/10.1016/j.ygeno.2003.08.020
Publikováno v:
RNA. 10:1-4
RNA sequences that conform to the consensus sequence of 5′ splice sites but are not used for splicing occur frequently in protein coding genes. Mutational analyses have shown that suppression of splicing at such latent sites may be dictated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd5f9a74fb8e1c2374de8add67b66d6
https://doi.org/10.1261/rna.5112704
https://doi.org/10.1261/rna.5112704
Publikováno v:
Nucleic Acids Research. 31:1974-1983
One of the major forms of alternative splicing, which generates multiple mRNA isoforms differing in the precise combinations of their exon sequences, is exon skipping. While in constitutive splicing all exons are included, in the skipped pattern(s) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d06d1617db1c7f0f8399b3c9e05632
https://doi.org/10.1093/nar/gkg279
https://doi.org/10.1093/nar/gkg279
Autor:
Joseph Sperling, Elana Miriami, Galit Yahalom, Binghui Li, Chaim Wachtel, Gil Sharon, Ruth Sperling, Gilgi Friedlander
Publikováno v:
Proceedings of the National Academy of Sciences. 99:5277-5282
Pre-mRNA splicing involves recognition of a consensus sequence at the 5′ splice site (SS). However, only some of the many potential sites that conform to the consensus are true ones, whereas the majority remain silent and are not normally used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64823bbf43985ca55185e0984dcff8e9
https://doi.org/10.1073/pnas.082095299
https://doi.org/10.1073/pnas.082095299
Publikováno v:
Journal of structural biology. 140(1-3)
Splice site selection is a key element of pre-mRNA splicing and involves specific recognition of consensus sequences at the 5(') and 3(') splice sites. Evidently, the compliance of a given sequence with the consensus 5(') splice site sequence is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17862f02fda78660ef65998b4b4feb4d
https://pubmed.ncbi.nlm.nih.gov/12490159
https://pubmed.ncbi.nlm.nih.gov/12490159
We have previously shown that specific nuclear pre-mRNA transcripts and their splicing products, as well as the general population of nuclear poly(A)+ RNA, are packaged in large nuclear ribonucleoprotein (InRNP) particles that sediment at the 200S re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec07d10ca362778d20767ca89fad517
https://europepmc.org/articles/PMC38553/
https://europepmc.org/articles/PMC38553/
Publikováno v:
Nucleic acids research. 22(15)
The effect of heat shock on the packaging and splicing of nuclear CAD pre-mRNA, a transcript expressed constitutively from a non heat-inducible promoter, was studied in vivo in Syrian hamster cells. While mild heat shock did not affect significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcdcdc4154f1efa2d0034bbd08b0e10
https://pubmed.ncbi.nlm.nih.gov/7915031
https://pubmed.ncbi.nlm.nih.gov/7915031