Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma

Autor: Márcia Gaião Alves, Márcio Hideki Kodama, Elaine Zayas Marcelino da Silva, Bruno Belmonte Martinelli Gomes, Rodrigo Alberto Alves da Silva, Gabriel Viliod Vieira, Vani Maria Alves, Carol Kobori da Fonseca, Ana Carolina Santana, Nerry Tatiana Cecílio, Mara Silvia Alexandre Costa, Maria Célia Jamur, Constance Oliver, Thiago Mattar Cunha, Thomas H. Bugge, Paulo Henrique Braz-Silva, Leandro M. Colli, Katiuchia Uzzun Sales

Publikováno v: Translational Oncology, Vol 14, Iss 1, Pp 100970- (2021)

Background: Oral squamous cell carcinoma (OSCC) remains a challenging cancer to treat despite all the advances of the last 50 years. Kallikrein 5 (KLK5) is among the serine proteases implicated in OSCC development. However, whether the activity of KL

Externí odkaz: https://doaj.org/article/6a42300807d74a1ba74c2f75701820ff

Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines

Autor: Edismauro Garcia Freitas Filho, Elaine Zayas Marcelino da Silva, Camila Ziliotto Zanotto, Constance Oliver, Maria Célia Jamur

Publikováno v: Mediators of Inflammation, Vol 2016 (2016)

Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators. The present

Externí odkaz: https://doaj.org/article/2ae994dee8584851a94bafe2c6c9ede2

rPbPga1 from Paracoccidioides brasiliensis Activates Mast Cells and Macrophages via NFkB.

Autor: Clarissa Xavier Resende Valim, Elaine Zayas Marcelino da Silva, Mariana Aprigio Assis, Fabricio Freitas Fernandes, Paulo Sergio Rodrigues Coelho, Constance Oliver, Maria Célia Jamur

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 8, p e0004032 (2015)

BACKGROUND:The fungus Paracoccidioides brasiliensis is the leading etiological agent of paracoccidioidomycosis (PCM), a systemic granulomatous disease that typically affects the lungs. Cell wall components of P. brasiliensis interact with host cells

Externí odkaz: https://doaj.org/article/902c4898e0434f9d88e2de312af742df

Cross-linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines: An Advanced Study

Autor: Camila Ziliotto Zanotto, Elaine Zayas Marcelino da Silva, Maria Célia Jamur, Constance Oliver, Edismauro Garcia Freitas Filho

Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators. The present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee811351bb0b914c71a1a5dff42befe2

Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma

Autor: Leandro M. Colli, Bruno Belmonte Martinelli Gomes, Gabriel Viliod Vieira, Constance Oliver, Nerry T. Cecilio, Katiuchia Uzzun Sales, Thiago M. Cunha, Mara Sílvia Alexandre Costa, Paulo Henrique Braz-Silva, Carol Kobori da Fonseca, R. A. Silva, Márcio Hideki Kodama, Márcia Gaião Alves, Ana Carolina Santana, Thomas H. Bugge, Vani Maria Alves, Maria Célia Jamur, Elaine Zayas Marcelino da Silva

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100970-(2021)

Highlights • Approximately 650,000 people will be diagnosed this year with cancers of the oral cavity and pharynx worldwide. • The absence of biomarkers for the disease early detection contributes to the late diagnosis. • Despite some advances

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84a94c393dc05f57238c4c2df3d6625