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of 7
pro vyhledávání: '"Elaine Y. C. Hsia"'
Autor:
Elaine Y. C. Hsia, Ya Zhang, Hai Son Tran, Agnes Lim, Ya-Hui Chou, Ganhui Lan, Philip A. Beachy, Xiaoyan Zheng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The range of Hedgehog (Hh) signalling in the Drosophila imaginal disc is limited by Hh/receptor degradation at the anterior/posterior (A/P) compartment boundary. Here, the authors show that degradation is mediated by co-receptor proteins Ihog/Boi, wh
Externí odkaz:
https://doaj.org/article/d1ad42630bbe4e7ea6ccabf94efdcf2a
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104070 (2014)
Ciliary accumulation of signaling proteins must result from a rate of ciliary entry that exceeds ciliary exit, but approaches for distinguishing ciliary entry vs. exit are lacking. Using a photoconvertible fluorescent protein tag, we establish an ass
Externí odkaz:
https://doaj.org/article/a2afb73d97dd44798053512b67795892
Publikováno v:
Frontiers in Biology. 10:203-220
The Hedgehog (Hh) signaling pathway plays crucial roles both in embryonic development and in adult stem cell function. The timing, duration and location of Hh signaling activity need to be tightly controlled. Abnormalities of Hh signal transduction l
Autor:
Xiaoyan Zheng, Ya Zhang, Ya-Hui Chou, Hai Son Tran, Philip A. Beachy, Agnes Lim, Ganhui Lan, Elaine Y. C. Hsia
Publikováno v:
Nature communications, vol 8, iss 1
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The Drosophila Hedgehog receptor functions to regulate the essential downstream pathway component, Smoothened, and to limit the range of signaling by sequestering Hedgehog protein signal within imaginal disc epithelium. Hedgehog receptor function req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c97a832d41ea27761a942155de54009
https://escholarship.org/uc/item/3z08x3qh
https://escholarship.org/uc/item/3z08x3qh
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2015, 8 (379), ⟨10.1126/scisignal.aaa5622⟩
Science Signaling, American Association for the Advancement of Science, 2015, 8 (379), ⟨10.1126/scisignal.aaa5622⟩
Defects in the biogenesis of or transport through primary cilia affect Hedgehog protein signaling, and many Hedgehog pathway components traffic through or accumulate in cilia. The Hedgehog receptor, Patched, negatively regulates the activity and cili
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104070 (2014)
PLoS ONE
PLoS ONE
Ciliary accumulation of signaling proteins must result from a rate of ciliary entry that exceeds ciliary exit, but approaches for distinguishing ciliary entry vs. exit are lacking. Using a photoconvertible fluorescent protein tag, we establish an ass
Publikováno v:
Progress in molecular biology and translational science. 87
Chromosomal aberrations involving genes encoding members of the p160/SRC transcriptional coactivator family such as AIB1/ACTR and TIF2 implicated the coactivators in malignancy of human cells. Significant progress has been made in the last decade tow