Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elaine Y Chiang"'
Autor:
Maylene Kefeng Qiu, Rachel Hilburg, Robert A Burger, Abdallah S. Geara, Jonathan J. Hogan, Matthew Palmer, Elaine Y Chiang
Publikováno v:
Clinical Nephrology. 96:51-59
Background Bevacizumab is a recombinant monoclonal antibody against the vascular endothelial growth factor A (VEGF-A) ligand that is used in the management of various solid malignancies. The adverse effect profiles of angiogenesis inhibitors, such as
Autor:
R.A. Gruppo, D. Malan, J. Kapocsi, L. Nemes, C.R.M. Hay, L. Boggio, P. Chowdary, G. Tagariello, A. von Drygalski, F. Hua, M. Scaramozza, S. Arkin, C.R.J.R. Hermans, C. Claes, I. Hanes, I. Huyghe, C. Kantaridis, L.M. da Costa, M.‐N. Ndongo, W. Petit, E.M. Santagostino, A. Cannavo, M.R. Fasulo, M.E. Mancuso, A. Tosetto, G. Castaman, L. Candiotto, P. Radossi, E. Scarpa, M.P. Smith, A.E. Dick, R.A. Robson, D.S. Waaka, C.J. Wynne, Z.E. Punt, K.R. Kavakli, C. Balkan, M. Duyu, S. Goksel, B. Karapinar, A.R. Ozyurek, G. Saydam, D.Y. Karapinar, M. Laffan, C.M. Millar, P.I. Suppiah, C.K. Rizleigh, G.P. Chowdary, J.S. Davies, E.L. Fosbury, S. Gill, G.N. Pike, J. Varghese Thachil, M. Recht, J. Deutsche, J. Taylor, K.A. Kalinyak, E.S. Mullins, J.S. Palumbo, C.T. Quinn, C. Tarango, S. Tarabar, P.A. Chandler, L. Deats, S.R. Deshpande, N.U. Epstein, A.G. Hansson, S.S. Pawlak, D. Rudin, L.A.J. Valentino, N.C. Kakodkar, M.L. Simpson, P.F. Fogarty, Tami L. Bach, Elaine Y. Chiang, J.W. Adamson, C.S. Glass, N. Sidhu, T.D. Tucker‐Greene
Publikováno v:
Journal of Thrombosis and Haemostasis. 16:1984-1993
Essentials Marzeptacog alfa (activated) [MarzAA] is a novel variant of activated human factor VII. A phase 1 dose escalation trial of MarzAA was conducted in subjects with severe hemophilia. MarzAA was safe and tolerated at intravenous doses up to 30
Prevalence of and risk factors for cerebral microbleeds among adult patients with haemophilia A or B
Autor:
Ronald L. Wolf, Patrick F. Fogarty, Phyllis A. Gimotty, Thita Chiasakul, Elaine Y. Chiang, M. Kelty, Adam Cuker, Holleh D Husseinzadeh, Bryan Pukenas
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 24(2)
Cerebral microbleeds (CMBs) represent clinically silent haemorrhagic events. Cerebral microbleeds (CMBs) portend negative neurovascular and cognitive outcomes in the general population and are associated with cognitive impairment in persons with haem
Autor:
Brigit Brand, Alessandro Gringeri, Paul Giangrande, James J. Goedert, Michael Recht, Olga Katsarou, Ana Rosa Cid-Haro, Patrick F. Fogarty, Steven M. Wolinsky, Evelien P. Mauser-Bunschoten, Judith Lin, Kate Talks, Javier Martinez-Picado, Amy D. Shapiro, Amalio Telenti, Christine L. Kempton, Lucy Dorrell, David Goldstein, Jérôme Lane, Jerry S. Powell, Sara Colombo, Judith Dalmau, Jeremy J. Martinson, Johannes Oldenburg, Shehnaz K. Hussain, Barton F. Haynes, Michael Makris, Dimitrios A. Tsakiris, Amanda Stemke, Anne T. Neff, Stephen Moore, Shinichi Oka, Philip Kuriakose, Rathi V. Iyer, Jonathan T. Wilde, Peter William Collins, Maria Teresa Alvarez-Roman, Andrew J. McMichael, Rafael Parra, Françoise Boehlen, Paul J. McLaren, Deborah L Brown, Marilyn J. Manco-Johnson, Thynn Thynn Yee, Kimo C. Stine, Bonaventura Clotet, Kimberly Pelak, Jay H. Bream, Kristiina Peter-Salonen, Paula H B Bolton-Maggs, Elaine Y. Chiang, Lisa P. Jacobson, Mary Carrington, Lara Oyesiku, Anne Angelillo-Scherrer, Jacques Fellay, Kevin V. Shianna
Publikováno v:
Lane, Jérôme; McLaren, Paul J.; Dorrell, Lucy; Shianna, Kevin V.; Stemke, Amanda; Pelak, Kimberly; Moore, Stephen; Oldenburg, Johannes; Boehlen, Francoise; Alvarez-Roman, Maria Teresa; Angelillo-Scherrer, Anne; Bolton-Maggs, Paula H. B.; Brand, Brigit; Brown, Deborah; Chiang, Elaine; Cid-Haro, Ana Rosa; Clotet, Bonaventura; Collins, Peter; Colombo, Sara; Dalmau, Judith; ... (2013). A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. Human molecular genetics, 22(9), pp. 1903-1910. Oxford University Press 10.1093/hmg/ddt033
Human Molecular Genetics, Vol. 22, No 9 (2013) pp. 1903-1910
Human molecular genetics
Human Molecular Genetics, vol. 22, no. 9, pp. 1903-1910
Human Molecular Genetics, Vol. 22, No 9 (2013) pp. 1903-1910
Human molecular genetics
Human Molecular Genetics, vol. 22, no. 9, pp. 1903-1910
Human genetic variation contributes to differences in susceptibility to HIV-1 infection. To search for novel host resistance factors, we performed a genome-wide association study (GWAS) in hemophilia patients highly exposed to potentially contaminate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1c24750bfdac52d92b3d5e567a3f03
https://doi.org/10.1093/hmg/ddt033
https://doi.org/10.1093/hmg/ddt033
Publikováno v:
Current Drug Safety. 5:171-181
The thrombopoiesis-stimulating agents (TSAs) are a novel class of drugs for the treatment of chronic immune thrombocytopenia (ITP). Roimplostim and eltrombopag, the first two TSAs to enter clinical use, received regulatory approval in 2008 and stand
Publikováno v:
Blood. 111:915-923
Previous studies using intravital microscopy in a sickle cell disease (SCD) mouse model suggest that adherent leukocytes (WBCs) play a key role in vaso-occlusion by capturing circulating erythrocytes (RBCs) in venules. Commercial intravenous human ga
Publikováno v:
Nature Methods. 4:219-222
We present a simple method to identify the recruitment of leukocyte subsets and determine concurrent surface-receptor clustering in live mice. We show that CD45+ F4/80- Gr-1+ neutrophils are robustly recruited in surgery-activated cremasteric venules
Autor:
Elaine Y. Chiang, Paul S. Frenette
Publikováno v:
Hematology/Oncology Clinics of North America. 19:771-784
The vaso-occlusion model has evolved impressively over the past several decades from polymerization-based concepts to a complex, wide-ranging schema that involves multistep, heterogeneous, and interdependent interactions among sickle erythrocytes (SS
Autor:
Adam Cuker, Suman L. Sood, Barbara A. Konkle, Ara Metjian, Chengbin Wang, Elaine Y. Chiang, J. M. Soucie
Type 3 von Willebrand's disease (VWD) is a rare bleeding diathesis with complete or near complete deficiency of von Willebrand factor (VWF) and low factor VIII (FVIII) levels. In contrast, only FVIII is decreased in haemophilia A (HA). Both disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c29fb70cbbb2e59c1a3159b550f40e7
https://europepmc.org/articles/PMC4545639/
https://europepmc.org/articles/PMC4545639/
Autor:
Jung Eun Jang, Elaine Y. Chiang, Anna Julie Peired, Jungshan Chang, Paul S. Frenette, Andrés Hidalgo
Publikováno v:
Nature medicine
Selectins and their ligands mediate leukocyte rolling, allowing interactions with chemokines that lead to integrin activation and arrest. Here we show that E-selectin is crucial for generating a secondary wave of activating signals, transduced specif