Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elaine Waldron-Roby"'
Autor:
Elaine Waldron-Roby, Janine Hoerauf, Nicolas Arbez, Shanshan Zhu, Kirsten Kulcsar, Christopher A Ross
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141439 (2015)
The apoptotic cascade is an orchestrated event, whose final stages are mediated by effector caspases. Regulatory binding proteins have been identified for caspases such as caspase-3, -7, -8, and -9. Many of these proteins belong to the inhibitor of a
Externí odkaz:
https://doaj.org/article/089345109c2040cb96afee68de706957
Autor:
Erin E Watkin, Nicolas Arbez, Elaine Waldron-Roby, Robert O'Meally, Tamara Ratovitski, Robert N Cole, Christopher A Ross
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88284 (2014)
Phosphorylation has been shown to have a significant impact on expanded huntingtin-mediated cellular toxicity. Several phosphorylation sites have been identified on the huntingtin (Htt) protein. To find new potential therapeutic targets for Huntingto
Externí odkaz:
https://doaj.org/article/a760bb87c312433792c9a180b917b4e7
Autor:
Mikhail V. Pletnikov, Xiaofang Wang, Wenzhen Duan, Michael R. Hayden, Elaine Waldron-Roby, Erin E. Watkin, Rona K. Graham, Zhipeng Hou, Christopher A. Ross, Nicolas Arbez, Tamara Ratovitski, Deborah A. Swing, Lino Tessarollo, Mali Jiang, Susumu Mori
Publikováno v:
The Journal of Neuroscience. 32:183-193
Huntington's disease (HD) is caused by a polyglutamine expansion in the Huntingtin (Htt) protein. Proteolytic cleavage of Htt into toxic N-terminal fragments is believed to be a key aspect of pathogenesis. The best characterized putative cleavage eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842dc4acb615d91941c6a2a5d1f5e921
https://doi.org/10.1523/jneurosci.1305-11.2012
https://doi.org/10.1523/jneurosci.1305-11.2012
Autor:
Christopher A. Ross, Shanshan Zhu, Kirsten Kulcsar, Elaine Waldron-Roby, Nicolas Arbez, Janine Hoerauf
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0141439 (2015)
PLoS ONE, Vol 10, Iss 10, p e0141439 (2015)
The apoptotic cascade is an orchestrated event, whose final stages are mediated by effector caspases. Regulatory binding proteins have been identified for caspases such as caspase-3, -7, -8, and -9. Many of these proteins belong to the inhibitor of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33422a005fb1b56f75a8c36d7cf136eb
https://doi.org/10.1371/journal.pone.0141439
https://doi.org/10.1371/journal.pone.0141439
Autor:
Christopher A. Ross, Robert N. O'Meally, Nicolas Arbez, Tamara Ratovitski, Robert N. Cole, Elaine Waldron-Roby, Erin E. Watkin
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88284 (2014)
PLoS ONE
PLoS ONE
Phosphorylation has been shown to have a significant impact on expanded huntingtin-mediated cellular toxicity. Several phosphorylation sites have been identified on the huntingtin (Htt) protein. To find new potential therapeutic targets for Huntingto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84640b21ac0c9f58cdc4ee5693fc7d1
https://doi.org/10.1371/journal.pone.0088284
https://doi.org/10.1371/journal.pone.0088284