Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elaine V Hill"'
Autor:
Graham J Britton, Rachel Ambler, Danielle J Clark, Elaine V Hill, Helen M Tunbridge, Kerrie E McNally, Bronwen R Burton, Philomena Butterweck, Catherine Sabatos-Peyton, Lea A Hampton-O’Neil, Paul Verkade, Christoph Wülfing, David Cameron Wraith
Publikováno v:
eLife, Vol 6 (2017)
Notch is a critical regulator of T cell differentiation and is activated through proteolytic cleavage in response to ligand engagement. Using murine myelin-reactive CD4 T cells, we demonstrate that proximal T cell signaling modulates Notch activation
Externí odkaz:
https://doaj.org/article/75afcfe3d41645f7a11ec23c03da7a47
Autor:
T.H. Sky eNg, Graham J Britton, Elaine V Hill, Johan eVerhagen, Bronwen R Burton, David C Wraith
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Since the discovery of interleukin-10 (IL-10) in the 1980s, a large body of work has led to its recognition as a pleiotropic immunomodulatory cytokine that affects both the innate and adaptive immune systems. IL-10 is produced by a wide range of cell
Externí odkaz:
https://doaj.org/article/5bd656703d4e4b859741d19bdb44821d
Autor:
Guiscard Seebohm, Sebastian Neumann, Carsten Theiss, Tanja Novkovic, Elaine V Hill, Jeremy M Tavaré, Florian Lang, Michael Hollmann, Denise Manahan-Vaughan, Nathalie Strutz-Seebohm
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33889 (2012)
We previously showed that the serum- and glucocorticoid-inducible kinase 3 (SGK3) increases the AMPA-type glutamate receptor GluA1 protein in the plasma membrane. The activation of AMPA receptors by NMDA-type glutamate receptors eventually leads to p
Externí odkaz:
https://doaj.org/article/53d30c51b7ab4e8c8dafc959c34a8f75
Autor:
Ella R. Shepard, Anja Wegner, Elaine V. Hill, Bronwen R. Burton, Sarah Aerts, Evelien Schurgers, Brecht Hoedemaekers, Sky T. H. Ng, Heather B. Streeter, Lotta Jansson, David C. Wraith
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunotherapy with antigen-processing independent T cell epitopes (apitopes) targeting autoreactive CD4+ T cells has translated to the clinic and been shown to modulate progression of both Graves’ disease and multiple sclerosis. The model apitope (
Externí odkaz:
https://doaj.org/article/7703b64009ca4397b26c63d3a5da8fce
Autor:
Yikui Li, Helen M. Tunbridge, Graham J. Britton, Elaine V. Hill, Parisa Sinai, Silvia Cirillo, Clare Thompson, Farnaz Fallah-Arani, Simon J. Dovedi, David C. Wraith, Christoph Wülfing
Publikováno v:
Cells, Vol 10, Iss 2, p 418 (2021)
Peripheral immune regulation is critical for the maintenance of self-tolerance. Here we have investigated signaling processes that distinguish T cells with regulatory capability from effector T cells. The murine Tg4 T cell receptor recognizes a pepti
Externí odkaz:
https://doaj.org/article/706774bad1b745928cd69654126acc59
Autor:
Brecht Hoedemaekers, Evelien Schurgers, Sarah Aerts, Heather B Streeter, Ella R. Shepard, Sky T. H. Ng, Anja Wegner, Lotta Jansson, Elaine V. Hill, Bronwen R Burton, David C. Wraith
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Immunotherapy with antigen-processing independent T cell epitopes (apitopes) targeting autoreactive CD4+ T cells has translated to the clinic and been shown to modulate progression of both Graves’ disease and multiple sclerosis. The model apitope (
Autor:
Elaine V. Hill, Silvia Cirillo, Simon J. Dovedi, Christoph Wülfing, Helen M Tunbridge, Yikui Li, Farnaz Fallah-Arani, Clare Thompson, Parisa Sinai, David C. Wraith, Graham J. Britton
Publikováno v:
et al. 2021, ' A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability ', Cells, vol. 10, no. 2, 418, pp. 1-23 . https://doi.org/10.3390/cells10020418
Cells, Vol 10, Iss 418, p 418 (2021)
Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 418, p 418 (2021)
Cells
Volume 10
Issue 2
Peripheral immune regulation is critical for the maintenance of self-tolerance. Here we have investigated signaling processes that distinguish T cells with regulatory capability from effector T cells. The murine Tg4 T cell receptor recognizes a pepti
Autor:
Lea A Hampton-O’Neil, Elaine V. Hill, Danielle J Clark, Kerrie E. McNally, Catherine A Sabatos-Peyton, Philomena Butterweck, Christoph Wülfing, Rachel Ambler, Graham J. Britton, Paul Verkade, Helen M Tunbridge, David C. Wraith, Bronwen R Burton
Publikováno v:
eLife
Britton, G, Ambler, R C J, Clark, D, Hill, E, Tunbridge, H, McNally, K, Burton, B, Butterweck, P, Sabatos-Peyton, C, Hampton-O'Neil, L, Verkade, P, Wuelfing, C & Wraith, D 2017, ' PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton ', eLife, vol. 6, e20003 . https://doi.org/10.7554/eLife.20003
eLife, Vol 6 (2017)
Britton, G, Ambler, R C J, Clark, D, Hill, E, Tunbridge, H, McNally, K, Burton, B, Butterweck, P, Sabatos-Peyton, C, Hampton-O'Neil, L, Verkade, P, Wuelfing, C & Wraith, D 2017, ' PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton ', eLife, vol. 6, e20003 . https://doi.org/10.7554/eLife.20003
eLife, Vol 6 (2017)
Notch is a critical regulator of T cell differentiation and is activated through proteolytic cleavage in response to ligand engagement. Using murine myelin-reactive CD4 T cells, we demonstrate that proximal T cell signaling modulates Notch activation
Autor:
Krishna C. Yalla, Elaine Huston, George S. Baillie, Elaine V. Hill, Miles D. Houslay, Louisa C.Y. Lee, David Henderson, Catherine L. Sheppard, Daniel M. Houslay, Allan J. Dunlop, Lynne S. Cairns, Diana F. Anthony
Publikováno v:
Cellular Signalling. 26:1958-1974
In Rat-1 cells, the dramatic decrease in the levels of both intracellular cyclic 3'5' adenosine monophosphate (cyclic AMP; cAMP) and in the activity of cAMP-activated protein kinase A (PKA) observed in mitosis was paralleled by a profound increase in
Autor:
Christoph Wülfing, Elaine V. Hill, David C. Wraith, Paul Verkade, Danielle J Clark, Philomena Butterweck, Bronwen R Burton, Catherine A Sabatos-Peyton, Helen M Tunbridge, Graham J. Britton, Lea A Hampton-O’Neil, Kerrie E. McNally, Rachel Ambler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7db8ca8032b89d8a28085ac3e40291c
https://doi.org/10.7554/elife.20003.020
https://doi.org/10.7554/elife.20003.020