Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elaine Seah"'
Autor:
Isaac KS Ng, Joanne Lee, Christopher Ng, Bustamin Kosmo, Lily Chiu, Elaine Seah, Michelle Meng Huang Mok, Karen Tan, Motomi Osato, Wee-Joo Chng, Benedict Yan, Lip Kun Tan
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-7 (2018)
Abstract Background Germline mutations in the RUNX1 transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet Disorders with predisposition to Acute Myeloid Leukaemia (FPD/AML). While
Externí odkaz:
https://doaj.org/article/8c249a81b8d14b5089c05e46f981186b
Autor:
Chin Hin Ng, Jia Jin Low, Christopher Ng, Isaac Ks Ng, Benedict Yan, Wee Joo Chng, Lily Chiu, Elaine Seah, Kenneth Hon Kim Ban
Publikováno v:
Journal of Clinical Pathology. 70:1069-1073
Targeted next generation sequencing platforms have been increasingly utilised for identification of novel mutations in myeloid neoplasms, such as acute myeloid leukaemia (AML), and hold great promise for use in routine clinical diagnostics. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e755835abc5f11676661b1f0ab2e084b
https://doi.org/10.1136/jclinpath-2017-204440
https://doi.org/10.1136/jclinpath-2017-204440
Autor:
Zenia Tiang, Kenneth Hon Kim Ban, Wilson Lek Wen Tan, Roger Foo, Wee Joo Chng, Joanne Lee, Christopher Ng, Chin Hin Ng, Tin Wee Tan, Elaine Seah, Yongli Hu, Benedict Yan, Lily Chiu
Publikováno v:
Oncology Letters
Although bulk high-throughput genomic profiling studies have led to a significant increase in the understanding of cancer biology, there is increasing awareness that bulk profiling approaches do not completely elucidate tumor heterogeneity. Single-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0d3ef2eeb8b613b871caf7b6a9cd8c
https://doi.org/10.3892/ol.2017.5669
https://doi.org/10.3892/ol.2017.5669
Autor:
Lily Chiu, Bee Choo Tai, Christopher Ng, Wee Joo Chng, Mingxuan Lin, Benedict Yan, Zhaojin Chen, Isaac Ks Ng, Chin Hin Ng, Elaine Seah, Marcus Hwai Yik Tan, Kenneth Hon Kim Ban
Publikováno v:
Journal of Clinical Pathology. 70:669-676
Aims In recent years, genomic technologies have enabled the identification of mutations in acute myeloid leukaemia (AML). DNMT3A is a recurrently mutated epigenetic modifier gene in AML. To date, the prognostic significance of DNMT3A mutations has no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea366a607355223bdd7e51b1959493e
https://doi.org/10.1136/jclinpath-2016-204195
https://doi.org/10.1136/jclinpath-2016-204195
Autor:
Christopher Ng, Isaac Ks Ng, Wee Joo Chng, Michelle Meng Huang Mok, Elaine Seah, Bustamin Kosmo, Joanne Lee, Karen Tan, Lily Chiu, Benedict Yan, Lip Kun Tan, Motomi Osato
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-7 (2018)
Biomarker Research
Biomarker Research
Background Germline mutations in the RUNX1 transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet Disorders with predisposition to Acute Myeloid Leukaemia (FPD/AML). While several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e546afb71fc6e247036c7b32c957443
https://doi.org/10.1186/s40364-018-0130-2
https://doi.org/10.1186/s40364-018-0130-2
Autor:
Soh Hui Ling, Benedict Yan, Chin-Hin Ng, Wee Joo Chng, Prabhakaran Abinaya, Bustamin Kosmo, Elaine Seah, Christopher Ng
Publikováno v:
Clinical and Diagnostic Pathology. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::436146aa847ab729d1ef288c664a260e
https://doi.org/10.15761/cdp.1000129
https://doi.org/10.15761/cdp.1000129
Autor:
Te-Chih Liu, Liang Piu Koh, Peak-Ling Lee, Lily Chiu, Chin Hin Ng, Grace Moshi, Elaine Seah, Wee Joo Chng, Christopher Ng, Evelyn Siew-Chuan Koay, Kenneth Hon Kim Ban, Benedict Yan
Publikováno v:
Journal of Clinical Pathology. 69:652-654
Germline CEBPA -mutant acute myeloid leukaemia (AML) is uncommon. There have been reports of single kindreds and small series1–6 since its initial description in 2004;7 and the most comprehensive characterisation comprising 10 CEBPA -mutant familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::209a2e3e78cd1c01614a9364ceb49367
https://doi.org/10.1136/jclinpath-2016-203672
https://doi.org/10.1136/jclinpath-2016-203672
Autor:
Isaac Ks, Ng, Christopher, Ng, Jia Jin, Low, Lily, Chiu, Elaine, Seah, Chin Hin, Ng, Wee-Joo, Chng, Benedict, Yan, Kenneth H K, Ban
Publikováno v:
Journal of clinical pathology. 70(12)
Targeted next generation sequencing platforms have been increasingly utilised for identification of novel mutations in myeloid neoplasms, such as acute myeloid leukaemia (AML), and hold great promise for use in routine clinical diagnostics. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8eca75ee751c473d407615abb79586a4
https://pubmed.ncbi.nlm.nih.gov/28676493
https://pubmed.ncbi.nlm.nih.gov/28676493
Autor:
Marcus, Tan, Isaac K S, Ng, Zhaojin, Chen, Kenneth, Ban, Christopher, Ng, Lily, Chiu, Elaine, Seah, Mingxuan, Lin, Bee Choo, Tai, Benedict, Yan, Chin Hin, Ng, Wee-Joo, Chng
Publikováno v:
Journal of clinical pathology. 70(8)
In recent years, genomic technologies have enabled the identification of mutations in acute myeloid leukaemia (AML).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f32134ccc62b4e126f1a5012a810a2a2
https://pubmed.ncbi.nlm.nih.gov/28100593
https://pubmed.ncbi.nlm.nih.gov/28100593
Autor:
Tin Wee Tan, Lily Chiu, Chin Hin Ng, Wee Joo Chng, Pei Tee Huan, Peak-Ling Lee, Evelyn Siew-Chuan Koay, Kenneth Ban, Yongli Hu, Benedict Yan, Elaine Seah, Christopher Ng
Publikováno v:
Journal of clinical pathology. 69(9)
AimsPCR amplicon-based next-generation sequencing (NGS) panels are increasingly used for clinical diagnostic assays. Amplification bias is a well-known limitation of PCR amplicon-based approaches. We sought to characterise lower-performance amplicons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a3224554178a7f1ae7b47400b9969
https://pubmed.ncbi.nlm.nih.gov/26896490
https://pubmed.ncbi.nlm.nih.gov/26896490