Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elaine P. Lunsford"'
Autor:
Kazumasa Inoue, Fangbing Liu, Jack Hoppin, Elaine P. Lunsford, Christian Lackas, Jacob Hesterman, Robert E. Lenkinski, Hirofumi Fujii, John V. Frangioni
Publikováno v:
Molecular Imaging, Vol 10 (2011)
Microcalcification is a hallmark of breast cancer and a key diagnostic feature for mammography. We recently described the first robust animal model of breast cancer microcalcification. In this study, we hypothesized that high-resolution computed tomo
Externí odkaz:
https://doaj.org/article/8c862d8289c9413c83e0f75187fe3886
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 319K, Target inhibition after treatments with NVP-BKM120 in vivo. Tumor-bearing MMTV-CreBRCA1f/fp53+/- mice were biopsied before treatment, and tumor tissues harvested within 3 hours after the last treatment. Tissues were fixed and process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1398ed6f3fdcab01db488d89fe89b601
https://doi.org/10.1158/2159-8290.22529226.v1
https://doi.org/10.1158/2159-8290.22529226.v1
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 526K, FDG-uptake and CT-PET scanning of mice before and after 2 weeks of treatment with NVP-BKM120. Tumor-bearing female MMTV-CreBRCA1f/fp53+/- mice were imaged with PET-CT scans before and after treatments with NVP-BKM120 at 50 mg/kg/day.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b657504fec7d182fdbab88931d869
https://doi.org/10.1158/2159-8290.22529223.v1
https://doi.org/10.1158/2159-8290.22529223.v1
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 169K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aed6bc2eb311b19cfcc4c53528de3a
https://doi.org/10.1158/2159-8290.22529208
https://doi.org/10.1158/2159-8290.22529208
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 71K, In vitro responses of BRCA1-mutant breast cancer cell lines to treatments with NVP-BKM120 (1 muM), Olaparib (10 muM) or their combination. Cells were seeded in quadruplicate in 96-well plates and treated for 7 days as indicated. A. HC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141c3c8bd8873269a3d3412d1985e33e
https://doi.org/10.1158/2159-8290.22529217.v1
https://doi.org/10.1158/2159-8290.22529217.v1
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 137K, Effects of the combination of NVP-BKM120 and Olaparib (left pair, treated with NVP-BKM120 at 30 mg/kg/day and Olaparib at 50 mg/kg/day) and of Olaparib alone (right pair, 50 mg/kg/day). Mice were imaged before and after 3 daily treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205fb694d1494a35784fc344dc911ec4
https://doi.org/10.1158/2159-8290.22529220
https://doi.org/10.1158/2159-8290.22529220
Autor:
Gerburg M. Wulf, Lewis C. Cantley, John M. Asara, Ralph Scully, José Baselga, Pier Paolo Pandolfi, Caterina Nardella, Costas A. Lyssiotis, Katherine Spencer, Antonella Papa, Anbazhagan Rajendran, Judith Balmañà, Yasir H. Ibrahim, Elaine P. Lunsford, Hai Hu, Laura N. Burga, Ashish Juvekar
PDF file - 159K, Erk phosphorylation after treatments with NVP-BKM120 in vivo. Tumor tissues were harvested from MMTV-CreBRCA1f/fp53+/- mice within 3 hours after the last treatment with NVP-BKM120. Tissues were fixed and processed for immunohistochem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed73b3e47946d19e949944d065a9583
https://doi.org/10.1158/2159-8290.22529211
https://doi.org/10.1158/2159-8290.22529211
Autor:
James W. Wells, Mark C. Gebhardt, Stephen L. Lessnick, Frans Van Valen, Kyle Robichaud, Elaine P. Lunsford, Taha Merghoub, Regina P. O'Sullivan, Ryan M. Porter, Fangjun Liu, Christopher H. Evans
PDF file, 59K, Supplementary Figure S1. A typical example of Bilateral Inguinal Lymph node size 8 days after vaccination with the native peptide QQNPSYDSV (#14) or its modified derivative YLNPSVDSV (#24).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b24e416a4ca9ab4dbd192f596b240
https://doi.org/10.1158/1078-0432.22455225.v1
https://doi.org/10.1158/1078-0432.22455225.v1
Autor:
James W. Wells, Mark C. Gebhardt, Stephen L. Lessnick, Frans Van Valen, Kyle Robichaud, Elaine P. Lunsford, Taha Merghoub, Regina P. O'Sullivan, Ryan M. Porter, Fangjun Liu, Christopher H. Evans
Purpose: The Ewing sarcoma family of tumors (ESFT) comprises a group of aggressive, malignant bone, and soft tissue tumors that predominantly affect children and young adults. These tumors frequently share expression of the EWS-FLI-1 translocation, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a172191674f786558fd7011a5a486e9a
https://doi.org/10.1158/1078-0432.c.6522963
https://doi.org/10.1158/1078-0432.c.6522963
Autor:
Fangbing Liu, Elaine P Lunsford, Jingli Tong, Yoshitomo Ashitate, Summer L Gibbs, Jane Yu, Hak Soo Choi, Elizabeth P Henske, John V Frangioni
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38589 (2012)
TSC2-deficient cells can proliferate in the lungs, kidneys, and other organs causing devastating progressive multisystem disorders such as lymphangioleiomyomatosis (LAM) and tuberous sclerosis complex (TSC). Preclinical models utilizing LAM patient-d
Externí odkaz:
https://doaj.org/article/da74b20d51ab4bad9e3ce6e707bd59a6