Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elaine M Morazzani"'
Autor:
Zach N Adelman, Michelle A E Anderson, Michael R Wiley, Marta G Murreddu, Glady Hazitha Samuel, Elaine M Morazzani, Kevin M Myles
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2239 (2013)
The impact of global climate change on the transmission dynamics of infectious diseases is the subject of extensive debate. The transmission of mosquito-borne viral diseases is particularly complex, with climatic variables directly affecting many par
Externí odkaz:
https://doaj.org/article/0e6f528f6f79445eb3e8b32ed01c43b0
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002470 (2012)
The natural maintenance cycles of many mosquito-borne pathogens require establishment of persistent non-lethal infections in the invertebrate host. The mechanism by which this occurs is not well understood, but we have previously shown that an antivi
Externí odkaz:
https://doaj.org/article/677cc73d31e24d698d2c1151e32e939f
Autor:
Elena K. Gaidamakova, Elaine M. Morazzani, Barbara Knollmann-Ritschel, Radha K. Maheshwari, Pamela J. Glass, Michael J. Daly, Manoshi Gayen, Paridhi Gupta
Publikováno v:
Vaccine. 35:3672-3681
Over the last ten years, Chikungunya virus (CHIKV), an Old World alphavirus has caused numerous outbreaks in Asian and European countries and the Americas, making it an emerging pathogen of great global health importance. Venezuelan equine encephalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57c0e75eedaf8c502273b173b0ccf28
https://doi.org/10.1016/j.vaccine.2017.05.016
https://doi.org/10.1016/j.vaccine.2017.05.016
Autor:
Wenjuan Ye, Patricia M. Legler, Jonah Cheung, Pamela J. Glass, Xin Hu, Dagmar H. Leary, Noel Southall, Mark A. Olson, Elaine M. Morazzani, Ajit Jadhav, Michael S. Lee, Mark Ferrer, Jaimee R. Compton, Juan J. Marugan
Publikováno v:
Biochemistry
The Venezuelan equine encephalitis virus (VEEV) nonstructural protein 2 (nsP2) cysteine protease (EC 3.4.22.-) is essential for viral replication and is involved in the cytopathic effects (CPE) of the virus. The VEEV nsP2 protease is a member of MERO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcef0376bea69f40da4cab929560fe1f
Autor:
Juan J. Marugan, Patricia M. Legler, Dagmar H. Leary, Jaimee R. Compton, Pamela J. Glass, Elaine M. Morazzani, Angela V. Berry, Xin Hu
Publikováno v:
Antiviral Res
The alphaviral nonstructural protein 2 (nsP2) cysteine proteases (EC 3.4.22.-) are essential for the proteolytic processing of the nonstructural (ns) polyprotein and are validated drug targets. A common secondary role of these proteases is to antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9954a5b16662a042b7f953b536ac9e94
https://pubmed.ncbi.nlm.nih.gov/30742841
https://pubmed.ncbi.nlm.nih.gov/30742841
Autor:
Pamela J. Glass, Sarah L. Norris, Keith A. Koistinen, Mitchell K. Monninger, Cynthia A. Rossi, Kathleen A. Kuehl, Ashley E. Piper, Elaine M. Morazzani, Mei G. Sun, Brian J. Kearney, David P Fetterer, Candace D. Blancett
Publikováno v:
Journal of virological methods. 248
A method for accurate quantitation of virus particles has long been sought, but a perfect method still eludes the scientific community. Electron Microscopy (EM) quantitation is a valuable technique because it provides direct morphology information an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050da0934f599a1604ebd848756376b2
https://pubmed.ncbi.nlm.nih.gov/28668710
https://pubmed.ncbi.nlm.nih.gov/28668710
Autor:
Manoshi, Gayen, Paridhi, Gupta, Elaine M, Morazzani, Elena K, Gaidamakova, Barbara, Knollmann-Ritschel, Michael J, Daly, Pamela J, Glass, Radha K, Maheshwari
Publikováno v:
Vaccine. 35(29)
Over the last ten years, Chikungunya virus (CHIKV), an Old World alphavirus has caused numerous outbreaks in Asian and European countries and the Americas, making it an emerging pathogen of great global health importance. Venezuelan equine encephalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d3f4e4c856aeb056ee865b4ccf9d496
https://pubmed.ncbi.nlm.nih.gov/28576570
https://pubmed.ncbi.nlm.nih.gov/28576570
Publikováno v:
RNA Biology. 6:387-391
The continual transmission in nature of many arthropod-borne viruses depends on the establishment of a persistent, nonpathogenic infection in a mosquito vector. The importance of antiviral immunity directed by small RNAs in the mechanism by which alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50ce2b4ffb84e1d5b46df89a7dea8ee
https://doi.org/10.4161/rna.6.4.8946
https://doi.org/10.4161/rna.6.4.8946
Publikováno v:
Proceedings of the National Academy of Sciences. 105:19938-19943
Mosquito-borne viruses cause significant levels of morbidity and mortality in humans and domesticated animals. Maintenance of mosquito-borne viruses in nature requires a biological transmission cycle that involves alternating virus replication in a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de091b6df39b864eefca94c95e727b91
https://doi.org/10.1073/pnas.0803408105
https://doi.org/10.1073/pnas.0803408105
Publikováno v:
Insect Biochemistry and Molecular Biology. 38:705-713
The RNA interference pathway functions as an antiviral defense in invertebrates. In order to generate a phenotypic marker which “senses” the status of the RNAi pathway in Aedes aegypti, transgenic strains were developed to express EGFP and DsRED
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54cd10c08e27475dc31d569128bb223
https://doi.org/10.1016/j.ibmb.2008.04.002
https://doi.org/10.1016/j.ibmb.2008.04.002