Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elaine Langenfeld"'
Autor:
Arindam Mondal, Rachel NeMoyer, Mehul Vora, Logan Napoli, Zoya Syed, Elaine Langenfeld, Dongxuan Jia, Youyi Peng, John Gilleran, Jacques Roberge, Christopher Rongo, Salma K. Jabbour, John Langenfeld
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Recent studies have shown that bone morphogenetic protein receptor 2 (BMPR2) regulates cell survival signaling events in cancer cells independent of the BMP type 1 receptor (BMPR1) or the Smad-1/5 transcription factor. Mutations i
Externí odkaz:
https://doaj.org/article/69e13be64bb24a12811f30521a80e6ca
Autor:
Rachel NeMoyer, Arindam Mondal, Mehul Vora, Elaine Langenfeld, Danea Glover, Michael Scott, Lauren Lairson, Christopher Rongo, David J. Augeri, Youyi Peng, Salma K. Jabbour, John Langenfeld
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Externí odkaz:
https://doaj.org/article/2da84e359a5b431a95cdf69e0681c9f3
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61256 (2013)
Bone morphogenetic proteins (BMPs) are highly conserved morphogens that are essential for normal development. BMP-2 is highly expressed in the majority of non-small cell lung carcinomas (NSCLC) but not in normal lung tissue or benign lung tumors. The
Externí odkaz:
https://doaj.org/article/24435ea8697b4e59afe06ed99d8d8444
Autor:
Salma K. Jabbour, John Langenfeld, Elaine Langenfeld, Logan Napoli, Jacques Roberge, Arindam Mondal, Youyi Peng, Dongxuan Jia, John A. Gilleran, Christopher Rongo, Zoya Syed, Rachel NeMoyer, Mehul Vora
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-15 (2021)
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-15 (2021)
BackgroundRecent studies have shown that bone morphogenetic protein receptor 2 (BMPR2) regulates cell survival signaling events in cancer cells independent of the BMP type 1 receptor (BMPR1) or the Smad-1/5 transcription factor. Mutations in BMPR2 tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb4478bc0be2fd7b129abd3e46cfdc
https://pubmed.ncbi.nlm.nih.gov/34563224
https://pubmed.ncbi.nlm.nih.gov/34563224
Autor:
John A. Gilleran, Arindam Mondal, Jacques Roberge, Michael Scott, Elaine Langenfeld, Andrew Zloza, David J. Augeri, John Langenfeld, Danea Glover, Rachel NeMoyer, Lauren Lairson, Youyi Peng
Background: Bone morphogenetic protein (BMP) is an evolutionarily conserved morphogen that is reactivated in lung carcinomas. BMP receptor inhibitors promote cell death of lung carcinomas by mechanisms not fully elucidated. The studies here reveal no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26fa0d1896b8ebc32cee2bc3155473e
https://doi.org/10.21203/rs.3.rs-20532/v2
https://doi.org/10.21203/rs.3.rs-20532/v2
Autor:
Arindam Mondal, Jacques Roberge, Michael Scott, John A. Gilleran, Elaine Langenfeld, Andrew Zloza, Rachel NeMoyer, John Langenfeld, Lauren Lairson, Danea Glover, Youyi Peng, David J. Augeri
Background: BMP is an evolutionary conserved morphogen that is reactivated in lung carcinomas. BMP receptor inhibitors promote cell death of lung carcinomas by mechanisms not fully elucidated. The studies here reveal novel mechanisms by which the “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bed356959bff67a225add4661a03339
https://doi.org/10.21203/rs.3.rs-20532/v1
https://doi.org/10.21203/rs.3.rs-20532/v1
Autor:
Elaine Langenfeld, Mehul Vora, Michael Scott, Salma K. Jabbour, Arindam Mondal, John Langenfeld, Lauren Lairson, Danea Glover, David Augeri, Youyi Peng, Christopher Rongo, Rachel NeMoyer
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bf7061345ba9cf6fa1c0a833326604
https://doi.org/10.1186/s12964-019-0469-5
https://doi.org/10.1186/s12964-019-0469-5
Autor:
Charles B. Chesson, Jyoti Malhotra, Michael Goedken, Elaine Langenfeld, Shengguo Li, Christine Minerowicz, Jenna H. Newman, Michael J. Lee, Sachin R. Jhawar, Evita Sadimin, John Langenfeld, Saeed Tarabichi, Salma K. Jabbour, Mary O. Carayannopolous, Rachel NeMoyer, Andrew Zloza, Praveen K. Bommareddy, Natalie S. Dobias, David Augeri, John E. Kerrigan, Sh’Rae Marshall
Publikováno v:
Oncogene. 37(27)
BMP receptor inhibitors induce death of cancer cells through the downregulation of antiapoptotic proteins XIAP, pTAK1, and Id1-Id3. However, the current most potent BMP receptor inhibitor, DMH2, does not downregulate BMP signaling in vivo because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b3acea1341794da7ceeeb705400061
https://pubmed.ncbi.nlm.nih.gov/29622797
https://pubmed.ncbi.nlm.nih.gov/29622797
Publikováno v:
Cancer Research. 79:2630-2630
Bone morphogenetic protein receptor (BMP) inhibitors have been shown to induce death of lung cancer cells, which involves the downregulation of x-linked inhibitor of apoptosis protein (XIAP). XIAP is a potent inhibitor of executioner caspases that pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a0784008c0bc03f4086ade1eb5e813
https://doi.org/10.1158/1538-7445.am2019-2630
https://doi.org/10.1158/1538-7445.am2019-2630
Autor:
Micheal J. Lee, Charles B. Chesson, Michael Goedken, Natalie S. Dobias, Evita Sadimin, Sachin R. Jhawar, Saeed Tarabichi, Praveen K. Bommareddy, John Langenfeld, Elaine Langenfeld, Salma K. Jabbour, Mary O. Carayannopolous, David Augeri, Christine Minerowicz, Jyoti Malhotra, Shengguo Li, John E. Kerrigan, Rachel NeMoyer, Andrew Zloza, Jenna H. Newman, Sh’Rae Marshall
Publikováno v:
Cancer Research. 78:LB-189
Purpose: Studies have shown that bone morphogenetic protein (BMP) signaling is aberrantly expressed in lung and other carcinoma leading to pro-oncogenic effects on tumor growth. The BMP receptor inhibitor DMH2 induces death of lung cancer cells throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cd63e62cbaafd721b28c0035ea42756
https://doi.org/10.1158/1538-7445.am2018-lb-189
https://doi.org/10.1158/1538-7445.am2018-lb-189