Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elaine L. Gong"'
Autor:
M La Belle, Elaine L. Gong, Diane L. Tribble, Ronald M. Krauss, Berbie M. Chu, B.R. Kullgren, J.O. Nagy
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 10, Pp 1666-1672 (2000)
We previously reported that upper thoracic expo- sure to ionizing radiation (IR) accelerates fatty streak forma- tion in C57BL/6 mice and that such effects are inhibited by overexpression of the antioxidant enzyme CuZn-superoxide dismutase (SOD). Not
Autor:
Christiaan Leeuwenburgh, Judy G. Verstuyft, Jay W. Heinecke, Charles J. Epstein, Elaine L. Carlson, Elaine L. Gong, Diane L. Tribble
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:1734-1740
Abstract Studies in vitro have shown that copper-zinc superoxide dismutase (CuZn-SOD) inhibits a number of events putatively involved in atherogenesis, including cell-mediated oxidation of LDL. To investigate whether increased activity of CuZn-SOD re
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 16:1580-1587
Although the nature and consequences of oxidative changes in the chemical constituents of low density lipoproteins (LDLs) have been extensively examined, the physical dynamics of LDL oxidation and the influence of physical organization on the biologi
Publikováno v:
Journal of Biological Chemistry. 271:5984-5987
The role of apolipoprotein A-II (apoA-II) in high density lipoprotein (HDL) structure and metabolism has been studied previously in transgenic mice overexpressing either human or murine apoA-II. These studies have shown differences between these two
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1215:141-149
The influence of sodium oleate (oleate) on complexing of apolipoprotein A-I (apo A-I) with egg yolk phosphatidylcholine (EYPC) was evaluated. Without the use of additional detergent such as sodium cholate, oleate facilitates formation of a single com
Autor:
Elaine L. Gong, S M Clift, Edward M. Rubin, Mark R. McCall, Joshua R. Schultz, Alex V. Nichols
Publikováno v:
Journal of Biological Chemistry. 267:21630-21636
Apolipoproteins A-I and A-II comprise approximately 70 and 20%, respectively, of the total protein content of HDL. Evidence suggests that apoA-I plays a central role in determining the structure and plasma concentration of HDL, while the role of apoA
Autor:
Trudy M. Forte, Elaine L. Gong, Patricia J. Blanche, Orsolya Genzel-Boroviczeny, Alex V. Nichols
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1085:306-314
High density lipoproteins (HDL) in human cord blood have previously been shown to exhibit particle size profiles distinctly different from those of adult HDL. The adult HDL profile is comprised of separate contributions from two major apolipoprotein-
Autor:
Trudy M. Forte, Long, Thomas A. Musliner, Elaine L. Gong, Ronald M. Krauss, Alex V. Nichols, Patricia J. Blanche
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 6, Pp 917-933 (1991)
Incubation of low (LDL), intermediate (IDL), or very low density lipoproteins (VLDL) with palmitic acid and either high density lipoproteins (HDL), delipidated HDL, or purified apolipoprotein (apo) A-I resulted in the formation of lipoprotein particl
Autor:
Richard M. Lawn, C. Doucet, Elaine L. Gong, Joëlle Thillet, Veena Afzal, Thierry Huby, Edward M. Rubin, M. John Chapman
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 23(9)
Objective— The apolipoprotein(a) [apo(a)] gene locus is the major determinant of the circulating concentration of the atherothrombogenic lipoprotein Lp(a). In vitro analysis of the intergenic region between the apo(a) and plasminogen genes revealed
Publikováno v:
Nature. 365:762-764
HIGH-DENSITY lipoprotein (HDL) contains two major proteins, apolipoprotein A-I (apoA-I) and apolipoprotein A-II (apoA-II), comprising about 70% and 20% of the total HDL protein mass, respectively. HDL exists in human plasma in two main forms, one con