Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Elaine K. Thomas"'
Autor:
Elaine K. Thomas, Terry J. Fry, Crystal L. Mackall, Veena Kapoor, Manoj Sinha, Ronald E. Gress, Matthew Milliron, Yu-Waye Chu
Publikováno v:
Blood. 104:2794-2800
Despite recent progress in our understanding of the biology of T-cell homeostasis, clinically available therapies to substantially improve immune reconstitution in patients sustaining T-cell depletion are lacking. T cells are regenerated via a dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c0424cc5cacb232a39c4d9b27fa646
https://doi.org/10.1182/blood-2003-11-3789
https://doi.org/10.1182/blood-2003-11-3789
Publikováno v:
Blood. 103:2699-2704
The CD8+ cell noncytotoxic anti-HIV response (CNAR) is associated with a long-term healthy clinical state in HIV-infected individuals. Over time CNAR is reduced concomitant with progression to disease. In studies to evaluate whether the interaction b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848dae1dfa0e7d97af3bf46a5e47dbff
https://doi.org/10.1182/blood-2003-06-1913
https://doi.org/10.1182/blood-2003-06-1913
Publikováno v:
The Journal of Immunology. 172:3725-3735
Dendritic cells (DCs) reside in tissues, where they function as sentinels, providing an essential link between innate and adaptive immunity. Increasing the numbers of DCs in vivo augments T cell responses, and can cause dramatic CTL-dependent tumor r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4b5514079c2ff96a7973f452fdc0f9
https://doi.org/10.4049/jimmunol.172.6.3725
https://doi.org/10.4049/jimmunol.172.6.3725
Autor:
Jeffrey A. Toretsky, Elaine K. Thomas, Jeffrey Summers, Melinda S. Merchant, Yvona Ward, Crystal L. Mackall, Chand Khanna, Lee J. Helman, Hua Zhang, Carl H. June, Bill Telford, Kevin S. Chua
Publikováno v:
Cancer Biology & Therapy. 2:579-586
Inadequate costimulation by solid tumors is generally believed to induce immune tolerance during primary tumor growth. We looked for tumor-specific immunity vs. tolerance in patients with Ewing's sarcoma. Circulating T cells from patients with progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3c13f29e7e266d658b49f8b0db1073
https://doi.org/10.4161/cbt.2.5.545
https://doi.org/10.4161/cbt.2.5.545
Autor:
Kenneth L. Bost, Laura W. Schrum, Betsy R. Butler, Ian Marriott, Elaine K. Thomas, Michael C. Hudson
Publikováno v:
Infection and Immunity. 71:1209-1216
Bacterially induced bone infections often result in significant local inflammatory responses which are coupled with loss of bone. However, the mechanisms necessary for the protective host response, or those responsible for pathogen-induced bone loss,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d7658f58988e363c22110a05786cfe
https://doi.org/10.1128/iai.71.3.1209-1216.2003
https://doi.org/10.1128/iai.71.3.1209-1216.2003
Autor:
Daniel Scott-Algara, Elaine K. Thomas, Françoise Vuillier, Karim Maloum, Gérard Dumas, Pablo Oppezzo, C. Magnac, Béatrice Payelle-Brogard, Gijillaume Dighiero
Publikováno v:
British Journal of Haematology. 120:243-250
Summary. Idiotypic structures of immunoglobulins from malignant B cells constitute tumour-specific antigens, though the function of immunoglobulin-specific CD8+ T cells in disease control and rejection remains unclear. We have studied five cases of B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67058526b482b8b96dec19bfb8dda915
https://doi.org/10.1046/j.1365-2141.2003.04075.x
https://doi.org/10.1046/j.1365-2141.2003.04075.x
Autor:
Paul J. Mosca, Timothy M. Clay, H. Kim Lyerly, Michael A. Morse, Dania Caron, Amy Hobeika, Kirsten Colling, Elaine K. Thomas
Publikováno v:
Journal of Leukocyte Biology. 72:546-553
The ligand for the receptor tyrosine kinase fms-like tyrosine kinase 3 (Flt3L) is a growth factor for hematopoietic progenitors and induces expansion of the two distinct lineages of dendritic cells (DC) that have been described in humans. These two l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3878cecddcf4e7cc935befe359a50878
https://doi.org/10.1189/jlb.72.3.546
https://doi.org/10.1189/jlb.72.3.546
Autor:
Catherine Sanders, Nina Bhardwaj, Selin Somersan, Elaine K. Thomas, Jean-François Fonteneau, Kara Bickham, Marie Larsson, Karsten Mahnke
Publikováno v:
European Journal of Immunology. 31:3432-3442
Dendritic cells (DC) utilize at least two pathways to process viral antigens onto MHC class I molecules. The conventional endogenous route is used to acquire antigens from both infectious and non-replicating virions. Exogenous pathways are used by DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b87eb31407c2e75af989296d8455ae
https://doi.org/10.1002/1521-4141(200112)31:12<3432::aid-immu3432>3.0.co
https://doi.org/10.1002/1521-4141(200112)31:12<3432::aid-immu3432>3.0.co
Autor:
Elaine K. Thomas, Colette Jouanne, Daniel Scott-Algara, Guillaume Dighiero, Karim Maloum, Françoise Vuillier
Publikováno v:
British Journal of Haematology. 115:831-844
Chronic lymphocytic leukaemia (CLL) remains an incurable disease. Although modern available treatments are able to induce disease regression, relapse almost inexorably occurs. Therefore, novel therapeutic strategies aimed at reducing the disease rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7402fbf8f5e6c08be3689e7a4cace9fb
https://doi.org/10.1046/j.1365-2141.2001.03223.x
https://doi.org/10.1046/j.1365-2141.2001.03223.x
Publikováno v:
European Journal of Immunology. 31:360-368
Langerhans cells (LC) represent dendritic cells (DC) within mucosal epithelium that are purported initial targets for HIV following sexual exposure to virus. Here, morphologic, phenotypic, functional and HIV infection experiments were performed using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::403dc356b57a71f0279f3a8260aec1e0
https://doi.org/10.1002/1521-4141(200102)31:2<360::aid-immu360>3.0.co
https://doi.org/10.1002/1521-4141(200102)31:2<360::aid-immu360>3.0.co