Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elaine J. Tanhehco"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1618-H1625
Mature cardiac myocytes are terminally differentiated, and the heart has limited capacity to replace lost myocytes. Thus adaptation of myocyte size plays an important role in the determination of cardiac function. The hypothesis tested is that regula
Autor:
Pervaiz A. Chaudhry, Sharad Rastogi, Anastassia Todor, Takayuki Mishima, Hani N. Sabbah, Sudhish Mishra, Albertas I. Undrovinas, Elaine J. Tanhehco, George Suzuki, Victor G. Sharov, Ramesh C Gupta
Publikováno v:
Circulation Research. 93:1095-1101
Passive mechanical containment of failing left ventricle (LV) with the Acorn Cardiac Support Device (CSD) was shown to prevent progressive LV dilation in dogs with heart failure (HF) and increase ejection fraction. To examine possible mechanisms for
Autor:
Victor G. Sharov, Hideaki Morita, Elaine J. Tanhehco, Anastassia Todor, Hani N. Sabbah, George Suzuki
Publikováno v:
European Journal of Heart Failure. 5:121-129
Background: Apoptosis may contribute to the myocardial dysfunction associated with heart failure (HF). Activation of the p38 MAPK cascade can induce apoptosis in non-cardiac cells through increased expression of Fas-L, or through decreased expression
Autor:
Victor G. Sharov, Sidney Goldstein, Pervaiz A. Chaudhry, Elaine J. Tanhehco, Anastassia Todor, Hani N. Sabbah, Takayuki Mishima, George Suzuki, Sharad Rostogi, Omar Nass, Petros V. Anagnostopoulos, Ramesh C Gupta
Publikováno v:
British Journal of Pharmacology. 138:301-309
1. We examined the effects of eprosartan, an AT(1) receptor antagonist, on the progression of left ventricular (LV) dysfunction and remodelling in dogs with heart failure (HF) produced by intracoronary microembolizations (LV ejection fraction, EF 30
Autor:
Anastassia Todor, Ellen G. McMahon, Sidney Goldstein, Hideaki Morita, Victor G. Sharov, George Suzuki, Elaine J. Tanhehco, Hani N. Sabbah, Amy E. Rudolph, Takayuki Mishima
Publikováno v:
Circulation. 106:2967-2972
Background— In heart failure (HF), aldosterone has been implicated in the formation of reactive interstitial fibrosis, a maladaptation that contributes to left ventricular (LV) remodeling. Eplerenone is a novel selective aldosterone blocker. The pr
Autor:
Takayuki Mishima, Victor G. Sharov, George Suzuki, Sidney Goldstein, Anastassia Todor, Mitsuhiro Tanimura, Elaine J. Tanhehco, Hani N. Sabbah
Publikováno v:
Cardiovascular Drugs and Therapy. 16:209-214
Background. The diuretic actions of endogenously produced atrial natriuretic factor (ANF) may be beneficial in the treatment of chronic heart failure (CHF). Neutral endopeptidase (NEP) is the primary enzyme responsible for the degradation of ANF. The
Autor:
Ruth A. Washington, Elaine J. Tanhehco, Koji Yasojima, Benedict R. Lucchesi, Patrick L. McGeer
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H195-H201
Both free radicals and complement activation can injure tissue. Our study determined whether free radicals alter complement production by the myocardium. Isolated hearts from New Zealand White rabbits were perfused on a Langendorff apparatus and expo
Autor:
Keith B. Naylor, Benedict R. Lucchesi, James L. Park, Erin A. Booth, Elaine J. Tanhehco, Kenneth S. Kilgore
Publikováno v:
Journal of Cardiovascular Pharmacology. 34:153-161
Activation of the complement system contributes to the tissue destruction associated with myocardial ischemia/reperfusion. Pentosan polysulfate (PPS), a negatively charged sulfated glycosaminoglycan (GAG) and an effective inhibitor of complement acti
Publikováno v:
Managing Acute Decompensated Heart Failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f7a4c3f6f320b116d1f202fd031848
https://doi.org/10.4324/9780203421345_chapter_31
https://doi.org/10.4324/9780203421345_chapter_31
Autor:
Hani N. Sabbah, Takayuki Mishima, Hideaki Morita, Victor G. Sharov, Omar Nass, Sanjaya Khanal, George Suzuki, Sharad Rastogi, Elaine J. Tanhehco, Petros V. Anagnostopoulos, Sidney Goldstein
Publikováno v:
Cardiovascular drugs and therapy. 21(1)
Peroxisome proliferator-activated receptor gamma (PPARgamma) activators affect the myocardium through inhibition of inflammatory cytokines and metabolic modulation but their effect in the progression of heart failure is unclear. In the present study,