Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Elaine J, Carlson"'
Publikováno v:
J Inorg Biochem
Two samples of living blood cells and of cleared blood plasma from the Phlebobranch tunicate Ascidia ceratodes from Bodega Bay, California, and one of fresh Henze solution from A. ceratodes of Monterey Bay, California, have been examined using sulfur
Autor:
Laurence H. Tecott, Saunak Sen, Hao Xiong, Charles E. McCulloch, Elaine J. Carlson, Evan H. Goulding
Publikováno v:
Genetics. 189:305-316
In genetic studies, many interesting traits, including growth curves and skeletal shape, have temporal or spatial structure. They are better treated as curves or function-valued traits. Identification of genetic loci contributing to such traits is fa
Autor:
Elaine J. Carlson, Peilin Sheng, Jean Lud Cadet, Syed F. Ali, Charles J. Epstein, Richard B. Rothman
Publikováno v:
Journal of Neurochemistry. 62:380-383
Administration of methamphetamine (METH) to rats and nonhuman primates causes loss of terminals in the nigrostriatal dopaminergic system. The mechanism by which METH causes its neurotoxicity is not known. To evaluate further the role of oxyradicals i
Autor:
Thomas J, Urban, Chen, Yang, Leah L, Lagpacan, Chaline, Brown, Richard A, Castro, Travis R, Taylor, Conrad C, Huang, Douglas, Stryke, Susan J, Johns, Michiko, Kawamoto, Elaine J, Carlson, Thomas E, Ferrin, Esteban G, Burchard, Kathleen M, Giacomini
Publikováno v:
Pharmacogenetics and Genomics. 17:773-782
OCTN1 is a multispecific transporter of organic cations and zwitterions, including several clinically important drugs as well as the antioxidant ergothioneine. OCTN1 is highly expressed in the kidney, where it is thought to aid in active secretion of
Autor:
Elaine J. Carlson, Rebecca Lee Terrill, Melanie Lee Chang, Steven P. Hamilton, Karen L. Overall, Donna J. Dyer, Maria M. Bautista
Publikováno v:
Journal of Heredity. 98:428-437
The dog is an attractive model for genetic studies of complex disease. With drafts of the canine genome complete, a large number of single-nucleotide polymorphisms (SNPs) that are potentially useful for gene-mapping studies and empirical estimations
Autor:
Philip J. Rosenthal, Elaine J. Carlson, Jonathan M. Woo, Grant Dorsey, Bryan Greenhouse, Christian Dokomajilar, Alissa Myrick
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 75:836-842
Genotyping methods for Plasmodium falciparum drug efficacy trials have not been standardized and may fail to accurately distinguish recrudescence from new infection, especially in high transmission areas where polyclonal infections are common. We dev
Interaction of Methotrexate with Organic-Anion Transporting Polypeptide 1A2 and Its Genetic Variants
Autor:
Ilaria Badagnani, Esteban G. Burchard, Travis R. Taylor, Michiko Kawamoto, Richard A. Castro, Elaine J. Carlson, Douglas Stryke, Conrad C. Huang, Kathleen M. Giacomini, Claire M. Brett, Susan J. Johns, Thomas E. Ferrin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:521-529
Methotrexate (MTX) is used in patients with malignant and autoimmune diseases. This drug is primarily excreted unchanged in the urine, and its net excretion occurs via active secretory and reabsorptive processes. We characterized the interaction of M
Autor:
Elaine J. Carlson, Nathalie Chevallier, Kunlin Jin, David A. Greenberg, Sarah A. Sagi, Sandhya Sitaraman, Surita Banwait, Veronica Galvan, Anna Logvinova, Olivia Gorostiza, Dale E. Bredesen, Marina Ataie
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7130-7135
The deficits characteristic of Alzheimer's disease (AD) are believed to result, at least in part, from the neurotoxic effects of β-amyloid peptides, a set of 39–43 amino acid fragments derived proteolytically from β-amyloid precursor protein (APP
Autor:
Melanie De La Cruz, Esteban G. Burchard, Leah L. Lagpacan, Kathleen M. Giacomini, Elaine J. Carlson, Douglas Stryke, Travis R. Taylor, Claire M. Brett, Conrad C. Huang, Thomas J. Urban, Thomas E. Ferrin, Lara M. Mangravite, Susan J. Johns, Michiko Kawamoto, Andrew R. Erdman, Richard A. Castro, Wendy Chan
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F905-F912
The human organic anion transporter, OAT3 ( SLC22A8), plays a critical role in renal drug elimination, by mediating the entry of a wide variety of organic anions, including a number of commonly used pharmaceuticals, into the renal proximal tubular ce
Autor:
Susan J. Johns, Thomas E. Ferrin, Douglas Stryke, Esteban G. Burchard, Michiko Kawamoto, Richard A. Castro, Wendy Chan, Elaine J. Carlson, Conrad C. Huang, Kathleen M. Giacomini, Claire M. Brett, Ilaria Badagnani
Publikováno v:
The Pharmacogenomics Journal. 5:157-165
The human concentrative nucleoside transporter, CNT3 (SLC28A3), plays an important role in mediating the cellular entry of a broad array of physiological nucleosides and synthetic anticancer nucleoside analog drugs. As a first step toward understandi