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pro vyhledávání: '"Elaine Hemers"'
Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77579e003d1a3d9676e0a0473b67c987
https://doi.org/10.1158/0008-5472.22364625
https://doi.org/10.1158/0008-5472.22364625
Matrix metalloproteinase-7 (MMP-7) is localized to epithelial cells and is up-regulated in many cancers and in inflammation. We now report that MMP-7 targets a key mesenchymal cell type, the myofibroblast. Recombinant MMP-7 stimulated the proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233ccb0080ea67f909b115a3d253ec4d
https://doi.org/10.1158/0008-5472.c.6494292
https://doi.org/10.1158/0008-5472.c.6494292
Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a618b3f9ddc0f0ac39ae3d4b52d2756
https://doi.org/10.1158/0008-5472.22364631.v1
https://doi.org/10.1158/0008-5472.22364631.v1
Autor:
Andrea Varro, Islay Steele, Keith Bodger, Catherine McCaig, Sabine Przemeck, D. Mark Pritchard, David D. Kerrigan, Timothy C. Wang, Rod Dimaline, Elaine Hemers, Cédric Duval, Graham J. Dockray, Suhail Ahmed
Publikováno v:
Gastroenterology. 130:1754-1763
Background & Aims: Interactions between epithelial and stromal cells are important determinants of mucosal organization, but the signaling mechanisms are understood incompletely. Matrix metalloproteinase (MMP)-7 is produced uniquely in epithelia, may
Publikováno v:
Cancer Research. 65:7363-7369
Matrix metalloproteinase-7 (MMP-7) is localized to epithelial cells and is up-regulated in many cancers and in inflammation. We now report that MMP-7 targets a key mesenchymal cell type, the myofibroblast. Recombinant MMP-7 stimulated the proliferati
Publikováno v:
European Journal of Cancer. 61:S78
Introduction Glucose depravation, hypoxia, and acidosis are characteristic features of the central core most solid tumours. Myofibroblasts are stromal cells present in many such solid tumours including those of the colon, and they are known to be inv
Autor:
Sabine Przemeck, Andrea Varro, D. Mark Pritchard, Elaine Hemers, Timothy C. Wang, Susan Kenny, Keith Bodger, Catherine McCaig
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 292(4)
Chronic hypergastrinemia is associated with enterochromaffin-like (ECL) cell hyperplasia, which may progress to gastric carcinoid tumors. The latter consists of epithelial cells and stroma, and both compartments usually regress after normalization of
Autor:
Suhail Ahmed, Rod Dimaline, Adelina Pagliocca, Elaine Hemers, Chris Haigh, Andrea Varro, Debbie Archer, Graham J. Dockray
Publikováno v:
Gastroenterology. 123(1)
Background & Aims: The gastric hormone gastrin regulates acid secretion, gene expression, and the functional development and cellular composition of the gastric mucosa. Using a gene array, we sought to identify major, novel, gastrin-regulated genes.
Autor:
Rod Dimaline, Steven R. Pennington, Zara E. Khan, Adelina Pagliocca, Andrea Varro, Graham J. Dockray, Elaine Hemers
Publikováno v:
Gastroenterology. 124:A22
Publikováno v:
Cell and Tissue Research
Glucose deprivation, hypoxia and acidosis are characteristic features of the central core of most solid tumours. Myofibroblasts are stromal cells present in many such solid tumours, including those of the colon, and are known to be involved in all st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fda1aa782e13085459a2d3c9b497fc3
https://researchonline.ljmu.ac.uk/id/eprint/3301/1/art%3A10.1007%2Fs00441-016-2389-7.pdf
https://researchonline.ljmu.ac.uk/id/eprint/3301/1/art%3A10.1007%2Fs00441-016-2389-7.pdf