Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elaine Gersz"'
Autor:
Christoph Klenk, Maria Scrivens, Anina Niederer, Shuying Shi, Loretta Mueller, Elaine Gersz, Maurice Zauderer, Ernest S. Smith, Ralf Strohner, Andreas Plückthun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
G protein-coupled receptors are a major class of drug targets. Here, the authors develop a method whereby their biophysical and functional properties can be altered through directed evolution in mammalian cells, leading to variants exhibiting feature
Externí odkaz:
https://doaj.org/article/b76be3cffcda479f9ff2db12a5dfd09a
Autor:
Christoph Klenk, Maria Scrivens, Anina Niederer, Shuying Shi, Loretta Mueller, Elaine Gersz, Maurice Zauderer, Ernest Smith, Ralf Strohner, Andreas Plückthun
Low stability and poor expression levels are inherent in many G protein-coupled receptors, hindering structural and biophysical analyses. Directed evolution in bacterial or yeast display systems has been successfully used to overcome both limitations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cdab7895d213120ed492900825cbe37
https://doi.org/10.1101/2022.10.17.512578
https://doi.org/10.1101/2022.10.17.512578
Autor:
Suna Onengut-Gumuscu, Rebecca R. Pickin, Maria Faidas, Elaine Gersz, Stephen S. Rich, Noah Vogler
Publikováno v:
Diabetes. 67
Genetic studies of type 1 diabetes (T1D) have identified more than 40 risk loci, yet the causative genes in each locus is widely unknown. Here, we investigated a candidate gene in the 10q23.31 risk locus—FAD-dependent amine oxidase (RNLS). Variants
Autor:
Marsha Raines, Elaine Gersz
Publikováno v:
Neurology Now. 10:54
Publikováno v:
Annals of Surgical Oncology: An Oncology Journal for Surgeons; Mar2023 Suppl 1, Vol. 30, p1-257, 257p
Autor:
Hershey, Andrew D., Oskoui, Maryam, Pringsheim, Tamara, Holler‐Managan, Yolanda, Potrebic, Sonja, Billinghurst, Lori, Gloss, David, Licking, Nicole, Sowell, Michael, Victorio, M. Cristina, Gersz, Elaine, Vrijsen, Emily, Zanitsch, Heather, Yonker, Marcy, Mack, Kenneth, Gelfand, Amy A., Szperka, Christina L., Powers, Scott W.
Publikováno v:
Headache: The Journal of Head & Face Pain; Sep2019, Vol. 59 Issue 8, p1133-1143, 11p, 1 Chart
Autor:
Gersz, Elaine, Raines, Marsha
Publikováno v:
Neurology Now; Jun/Jul2014, Vol. 10 Issue 3, p54-54, 1p