Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elaine G. Bean"'
Autor:
Nicola Currey, Zeenat Jahan, C. Elizabeth Caldon, Phuong N. Tran, Fahad Benthani, Penelope De Lacavalerie, Daniel L. Roden, Brian S. Gloss, Claudia Campos, Elaine G. Bean, Amanda Bullman, Saskia Reibe-Pal, Marcel E. Dinger, Mark A. Febbraio, Stephen J. Clarke, Jane E. Dahlstrom, Maija R.J. Kohonen-Corish
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Background & Aims: The early events by which inflammation promotes cancer are still not fully defined. The MCC gene is silenced by promoter methylation in colitis-associated and sporadic colon tumors, but its functional significance in precancerous l
Externí odkaz:
https://doaj.org/article/3f5a2d0c39a64c9b94fae8baddfca8d1
Autor:
Wen Juan Tu, Robert D. McCuaig, Abel H. Y. Tan, Kristine Hardy, Nabila Seddiki, Sayed Ali, Jane E. Dahlstrom, Elaine G. Bean, Jenny Dunn, Jade Forwood, Sofia Tsimbalyuk, Kate Smith, Desmond Yip, Laeeq Malik, Thiru Prasanna, Peter Milburn, Sudha Rao
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Lysine specific demethylase 1 (LSD1) is a key epigenetic eraser enzyme implicated in cancer metastases and recurrence. Nuclear LSD1 phosphorylated at serine 111 (nLSD1p) has been shown to be critical for the development of breast cancer stem cells. H
Externí odkaz:
https://doaj.org/article/1c7f4fcca2a647ae881fda8cea07dc8e
Autor:
Dessislava N. Mladenova, Jane E. Dahlstrom, Phuong N. Tran, Fahad Benthani, Elaine G. Bean, Irvin Ng, Laurent Pangon, Nicola Currey, Maija R. J. Kohonen-Corish
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 9, Pp 1093-1103 (2015)
Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or
Externí odkaz:
https://doaj.org/article/c4eabf5f865941bdb4e7569db2f3fceb
Autor:
Fan Wu, Robert D. McCuaig, Christopher R. Sutton, Abel H. Y. Tan, Yoshni Jeelall, Elaine G. Bean, Jin Dai, Thiru Prasanna, Jacob Batham, Laeeq Malik, Desmond Yip, Jane E. Dahlstrom, Sudha Rao
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3080 (2019)
DUSP6 is a dual-specificity phosphatase (DUSP) involved in breast cancer progression, recurrence, and metastasis. DUSP6 is predominantly cytoplasmic in HER2+ primary breast cancer cells, but the expression and subcellular localization of DUSPs, espec
Externí odkaz:
https://doaj.org/article/e6781e87681a43368cdf759556af7cf2
Autor:
Jenny, Dunn, Robert D, McCuaig, Abel H Y, Tan, Wen Juan, Tu, Fan, Wu, Kylie M, Wagstaff, Anjum, Zafar, Sayed, Ali, Himanshu, Diwakar, Jane E, Dahlstrom, Elaine G, Bean, Jade K, Forwood, Sofiya, Tsimbalyuk, Emily M, Cross, Kristine, Hardy, Amanda L, Bain, Elizabeth, Ahern, Riccardo, Dolcetti, Roberta, Mazzieri, Desmond, Yip, Melissa, Eastgate, Laeeq, Malik, Peter, Milburn, David A, Jans, Sudha, Rao
Publikováno v:
Cancers. 14(6)
Protein kinase C (PKC)-θ is a serine/threonine kinase with both cytoplasmic and nuclear functions. Nuclear chromatin-associated PKC-θ (nPKC-θ) is increasingly recognized to be pathogenic in cancer, whereas its cytoplasmic signaling is restricted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::051427bf623ea13dff1f12cd3d6062b0
https://pubmed.ncbi.nlm.nih.gov/35326747
https://pubmed.ncbi.nlm.nih.gov/35326747
Autor:
Robert McCuaig, Yoshni Jeelall, Laeeq Malik, Jin Dai, Abel Tan, Christopher R Sutton, Desmond Yip, Fan Wu, Jacob Batham, Elaine G. Bean, Jane E. Dahlstrom, Sudha Rao, Thiru Prasanna
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3080 (2019)
Volume 20
Issue 12
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3080 (2019)
DUSP6 is a dual-specificity phosphatase (DUSP) involved in breast cancer progression, recurrence, and metastasis. DUSP6 is predominantly cytoplasmic in HER2+ primary breast cancer cells, but the expression and subcellular localization of DUSPs, espec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcecb62faa49ab4aaf4f178076bbe6f8
Autor:
Saskia Reibe-Pal, Mark A. Febbraio, Amanda Bullman, Brian S. Gloss, Elaine G. Bean, C. Elizabeth Caldon, Stephen Clarke, Marcel E. Dinger, Nicola Currey, Daniel L. Roden, Maija R.J. Kohonen-Corish, Phuong N. Tran, Penelope De Lacavalerie, Fahad Benthani, Jane E. Dahlstrom, Claudia Guimarães Camargo Campos, Zeenat Jahan
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Background & Aims The early events by which inflammation promotes cancer are still not fully defined. The MCC gene is silenced by promoter methylation in colitis-associated and sporadic colon tumors, but its functional significance in precancerous le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c468af758b15860c11906bdd37df6fef
Autor:
Mark E. Koina, Tailoi Chan-Ling, Louise Baxter, Jane E. Dahlstrom, Elaine G. Bean, Suzanne Hughes, Samuel J. Adamson, Ruth-Ann Sterling, Janet R. McColm
Publikováno v:
Experimental Eye Research. 92:361-376
Human fetal eyes 8-40 weeks gestation (WG) were examined using markers to hematopoietic stem cells (HSC), vascular precursor cells (VPC), monocytes/macrophages and endothelial cells (EC). Electron microscopy and bromo-deoxyuridene labeling were under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d2b038ced071dc0654e8b2c1c4b473
https://doi.org/10.1016/j.exer.2011.02.009
https://doi.org/10.1016/j.exer.2011.02.009
Publikováno v:
Biochemical and biophysical research communications. 413(2)
We describe a coculture model of a human intestinal epithelial cell line and human peripheral blood monocytes in which monocytes differentiate into cells with features of resident intestinal macrophages. Caco-2 cells are grown on the lower surface of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d491b85dafca820e66350d72148087d
https://pubmed.ncbi.nlm.nih.gov/21893047
https://pubmed.ncbi.nlm.nih.gov/21893047
Autor:
Tailoi Chan-Ling, Steven T.H. Yun, Elaine G. Bean, Samuel J. Adamson, Jane E. Dahlstrom, Mark E. Koina, Louise Baxter, Janet R. McColm
Publikováno v:
Investigative ophthalmologyvisual science. 52(1)
Purpose To examine mural cell differentiation and pericyte ensheathment during human choroidal vascular formation and into adulthood. Methods Triple- and double-labeled immunohistochemistry (alpha-smooth muscle actin [αSMA], desmin, NG2, calponin, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46525ed0339efd776c5e31ad1e273880
https://pubmed.ncbi.nlm.nih.gov/21169526
https://pubmed.ncbi.nlm.nih.gov/21169526