Sensitivity of different DNA extraction methods and PCR to detect resistance in patients with leprosy stratified by the bacilloscopic index

Autor: Lais Sevilha-Santos, Danielle Costa Aquino, Günter Hans Neto, Fabiano José Queiroz Costa, Carlos Augusto Felipe de Sousa, Elaine Faria Morelo, Agenor de Castro Moreira dos Santos Júnior, Ciro Martins Gomes

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 26, Iss 4, Pp 102381- (2022)

Introduction: Antimicrobial resistance in leprosy is an emerging problem, and the quantitative impact of low bacilloscopic indexes (BIs) on the sensitivity of molecular tests is unknown. We aimed to evaluate the sensitivity of gene sequencing for the

Externí odkaz: https://doaj.org/article/dc31406d722c4043972bd1b7ba738fe8

The interference of polypharmacy and the importance of clinical pharmacy advice in the treatment of leprosy: a case-control study

Autor: Elaine Faria Morelo, Daniel da Silva Marques, Ciro Martins Gomes, Raimunda Nonata Ribeiro Sampaio, Selma Regina Penha Silva Cerqueira, Carlos Augusto Felipe de Sousa, Lais Sevilha dos Santos, Agenor de Castro Moreira dos Santos Júnior, Renata Trindade Gonçalves, Gunter Hans Neto, Patrícia Shu Kurizky

Publikováno v: Revista da Sociedade Brasileira de Medicina Tropical
Revista da Sociedade Brasileira de Medicina Tropical, Vol 53
Revista da Sociedade Brasileira de Medicina Tropical, Volume: 53, Article number: e20200114, Published: 01 JUN 2020
Revista da Sociedade Brasileira de Medicina Tropical v.53 2020
Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT

INTRODUCTION: Although supervised doses are essential for reducing leprosy treatment failure, the impact of specific drug interactions has rarely been assessed. This study aimed to estimate the risk of leprosy treatment suspension in patients receivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e257155a530c592b3fb190148a285a
http://europepmc.org/articles/PMC7269535