Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elaine D. Por"'
Autor:
Katherine A. Burns, Amelia M. Pearson, Jessica L. Slack, Elaine D. Por, Alicia N. Scribner, Nazmin A. Eti, Richard O. Burney
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Endometriosis is a prevalent gynecologic condition associated with pelvic pain and infertility characterized by the implantation and growth of endometrial tissue displaced into the pelvis via retrograde menstruation. The mouse is a molecularly well-a
Externí odkaz:
https://doaj.org/article/b67b06e777eb4832af3bc2bd9c50ca4f
Autor:
Daniel J. Selig, Kevin S. Akers, Kevin K. Chung, Adrian T. Kress, Jeffrey R. Livezey, Elaine D. Por, Kaitlin A. Pruskowski, Jesse P. DeLuca
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 618 (2022)
Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics. However, it is unclear if one mechanism of critical illness alters PK more significantly
Externí odkaz:
https://doaj.org/article/87aa22adf20b46ba96bfbd205b5f2b80
Autor:
Daniel J Selig, Jeffrey R Livezey, Geoffrey C Chin, Jesse P DeLuca, Walter O Guillory II, Adrian T Kress, Thomas O Oliver, Elaine D Por
Publikováno v:
Military Medicine. 187:9-17
Introduction Clinical utilization of pharmacogenomics (PGx) testing is highly institutionally dependent, and little information is known about provider practices of PGx testing in the Military Health System (MHS). In this study, we aimed to character
Autor:
Elaine D, Por, Daniel J, Selig, Geoffrey C, Chin, Jesse P, DeLuca, Thomas G, Oliver, Jeffrey R, Livezey
Publikováno v:
Military Medicine. 187:1-8
Pharmacogenomics (PGx) plays a fundamental role in personalized medicine, providing an evidence-based treatment approach centered on the relationship between genomic variations and their effect on drug metabolism. Cytochrome P450 (CYP450) enzymes are
Publikováno v:
Military Medicine. 187:25-31
Introduction Providing patient-specific clinical care is an expanding focus for medical professionals and researchers, more commonly referred to as personalized or precision medicine. The goal of using a patient-centric approach is to provide safer c
Publikováno v:
Journal of Clinical Pharmacology
Continuous venovenous hemofiltration (CVVH) is a life‐sustaining procedure in patients with severe burns and acute kidney injury. Physiologic changes from burn injury and use of CVVH may alter imipenem pharmacokinetics (PK). We aimed to compare imi
Autor:
Daniel J. Selig, Jesse P. DeLuca, Kevin K. Chung, Kaitlin A. Pruskowski, Jeffrey R. Livezey, Robert J. Nadeau, Elaine D. Por, Kevin S. Akers
Publikováno v:
Journal of clinical pharmacy and therapeutics. 47(8)
Timely and appropriate dosing of antibiotics is essential for the treatment of bacterial sepsis. Critically ill patients treated with continuous kidney replacement therapy (CKRT) often have physiologic derangements that affect pharmacokinetics (PK) o
Autor:
Jeffrey R. Livezey, Thomas Oliver, Daniel J. Selig, Elaine D. Por, Jesse P. DeLuca, Adrian T. Kress, Rosenie Thelus Jean, Aaron J. Brown
Publikováno v:
Pharmacoepidemiology and Drug Safety. 29:1605-1615
PURPOSE To explore patterns of antimuscarinic medication as a risk factor for type 2 diabetes mellitus (T2DM). METHODS This is a retrospective cohort study of females 18 years or older within the Military Health System from 2006 to 2016. Administrati
Autor:
Daniel J. Selig, Kevin S. Akers, Jeffrey R. Livezey, Kevin K. Chung, Kaitlin A Pruskowski, Elaine D. Por
Publikováno v:
British journal of clinical pharmacology. 88(5)
Severe burn injury involves widespread skin and tissue damage leading to systemic inflammation, hypermetabolism and multi-organ failure. The hypermetabolic phase of burn injury has been associated with increased systemic antibiotic clearance; however
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics
Purpose: Proliferative vitreoretinopathy (PVR) is a blinding disorder that develops after a retinal tear or detachment. Activation of the retinal pigmented epithelium (RPE) is implicated in PVR; however, the mechanisms leading to enhanced RPE prolife