Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elaine D Por"'
Autor:
Elaine D Por, Melody L Sandoval, Chiquita Thomas-Benson, Teresa A Burke, Allison Doyle Brackley, Nathaniel A Jeske, Jeffery M Cleland, Brian J Lund
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182102 (2017)
Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor po
Externí odkaz:
https://doaj.org/article/69724b78f4d5470f9fec116a82b2d094
Autor:
Matthew P Rowan, Sonya M Bierbower, Michael A Eskander, Kalina Szteyn, Elaine D Por, Ruben Gomez, Nicholas Veldhuis, Nigel W Bunnett, Nathaniel A Jeske
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93688 (2014)
The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C). Post-translational modifications to TRPV1 result in dynamic changes to the sensitivity of recepto
Externí odkaz:
https://doaj.org/article/174209bf0b7846cfbc51fe6c24594614
Autor:
Daniel J. Selig, Kevin S. Akers, Kevin K. Chung, Adrian T. Kress, Jeffrey R. Livezey, Elaine D. Por, Kaitlin A. Pruskowski, Jesse P. DeLuca
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 618 (2022)
Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics. However, it is unclear if one mechanism of critical illness alters PK more significantly
Externí odkaz:
https://doaj.org/article/87aa22adf20b46ba96bfbd205b5f2b80
Autor:
Daniel J Selig, Jeffrey R Livezey, Geoffrey C Chin, Jesse P DeLuca, Walter O Guillory II, Adrian T Kress, Thomas O Oliver, Elaine D Por
Publikováno v:
Military Medicine. 187:9-17
Introduction Clinical utilization of pharmacogenomics (PGx) testing is highly institutionally dependent, and little information is known about provider practices of PGx testing in the Military Health System (MHS). In this study, we aimed to character
Autor:
Elaine D, Por, Daniel J, Selig, Geoffrey C, Chin, Jesse P, DeLuca, Thomas G, Oliver, Jeffrey R, Livezey
Publikováno v:
Military Medicine. 187:1-8
Pharmacogenomics (PGx) plays a fundamental role in personalized medicine, providing an evidence-based treatment approach centered on the relationship between genomic variations and their effect on drug metabolism. Cytochrome P450 (CYP450) enzymes are
Publikováno v:
Military Medicine. 187:25-31
Introduction Providing patient-specific clinical care is an expanding focus for medical professionals and researchers, more commonly referred to as personalized or precision medicine. The goal of using a patient-centric approach is to provide safer c
Publikováno v:
Journal of Clinical Pharmacology
Continuous venovenous hemofiltration (CVVH) is a life‐sustaining procedure in patients with severe burns and acute kidney injury. Physiologic changes from burn injury and use of CVVH may alter imipenem pharmacokinetics (PK). We aimed to compare imi
Autor:
Daniel J. Selig, Jesse P. DeLuca, Kevin K. Chung, Kaitlin A. Pruskowski, Jeffrey R. Livezey, Robert J. Nadeau, Elaine D. Por, Kevin S. Akers
Publikováno v:
Journal of clinical pharmacy and therapeutics. 47(8)
Timely and appropriate dosing of antibiotics is essential for the treatment of bacterial sepsis. Critically ill patients treated with continuous kidney replacement therapy (CKRT) often have physiologic derangements that affect pharmacokinetics (PK) o
Autor:
Jeffrey R. Livezey, Thomas Oliver, Daniel J. Selig, Elaine D. Por, Jesse P. DeLuca, Adrian T. Kress, Rosenie Thelus Jean, Aaron J. Brown
Publikováno v:
Pharmacoepidemiology and Drug Safety. 29:1605-1615
PURPOSE To explore patterns of antimuscarinic medication as a risk factor for type 2 diabetes mellitus (T2DM). METHODS This is a retrospective cohort study of females 18 years or older within the Military Health System from 2006 to 2016. Administrati
Autor:
Katherine A. Burns, Amelia M. Pearson, Jessica L. Slack, Elaine D. Por, Alicia N. Scribner, Nazmin A. Eti, Richard O. Burney
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2022)
Frontiers in Physiology, Vol 12 (2022)
Endometriosis is a prevalent gynecologic condition associated with pelvic pain and infertility characterized by the implantation and growth of endometrial tissue displaced into the pelvis via retrograde menstruation. The mouse is a molecularly well-a