Výsledky vyhledávání - "Elaine Aparecida Del, Bel"

Akademický článek

Effects of aging on nitrergic neurons in human striatum and subthalamic nucleus

Autor: Bruno Lopes dos Santos-Lobato, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas

Publikováno v: Arquivos de Neuro-Psiquiatria, Vol 73, Iss 9, Pp 779-783 (2015)

Nitric oxide (NO) is a major neurotransmitter associated with motor control in basal ganglia. Movement disorders, as essential tremor and Parkinson’s disease, are more prevalent on aged individuals. We investigated the effects of aging on neuronal

Externí odkaz: https://doaj.org/article/abd3b5e431ff4a45b5ae1a36aa5e2dd2

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Akademický článek

Influence of external factors on the preservation of human nervous tissue for histological studies: review article

Autor: Bruno Lopes dos Santos, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas

Publikováno v: Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 50, Iss 6, Pp 438-444 (2014)

Neuropathological studies are crucial for the new knowledge on pathophysiology and treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The postmortem brain tissue processing method directly impacts on both th

Externí odkaz: https://doaj.org/article/33ffe0ed95494c30bf4d39af0f4d84b2

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Akademický článek

Influência do estreitamento do canal vertebral e do tempo para a descompressão na recuperação locomotora de ratos Influencia del estrechamiento del canal vertebral y del tiempo para la descompresión en la recuperación locomotora de ratas The influence of spinal canal narrowing and timing of decompression on locomotion recovery of rats

Autor: Albert Schiaveto de Souza, Felipe Barros de Escobar, Elaine Aparecida Del Bel

Publikováno v: Coluna/Columna, Vol 8, Iss 2, Pp 117-126 (2009)

OBJETIVO: o objetivo deste trabalho foi estudar as consequências da lesão por contusão da medula espinhal, associada ao estreitamento do canal vertebral, no comportamento motor de ratos, avaliando-se o efeito do tempo para descompressão na recupe

Externí odkaz: https://doaj.org/article/c99b5ae6968741a1a8a8e17bae6a2c7b

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Akademický článek

Dopamina, óxido nítrico e suas interações em modelos para o estudo da esquizofrenia Dopamine, nitric oxide and their interactions in models for the study of schizophrenia

Autor: Cristiane Salum, Ana Carolina de Castro Issy Pereira, Elaine Aparecida Del Bel Belluz Guimarães

Publikováno v: Psicologia: Reflexão e Crítica, Vol 21, Iss 2, Pp 186-194 (2008)

Modelos experimentais baseados no aumento da neurotransmissão dopaminérgica mimetizam aspectos comportamentais e neuroquímicos característicos da esquizofrenia. Psicoestimulantes, como a anfetamina, são utilizados com esta finalidade, pois aumen

Externí odkaz: https://doaj.org/article/031b626b5da44d73894963c2e528df10

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Akademický článek

Dopamine, nitric oxide and their interactions in models for the study of schizophrenia / Dopamina, óxido nítrico e suas interações em modelos para o estudo da esquizofrenia

Autor: Cristiane Salum, Ana Carolina de Castro Issy Pereira, Elaine Aparecida Del Bel Belluz Guimarães

Publikováno v: Psicologia: Reflexão e Crítica, Vol 21, Iss 1, Pp 186-194 (2008)

Experimental models based on the increase of dopaminergic neurotransmission mimic behavioral and neurochemical schizophrenia-like aspects. Psychostimulants, as amphetamine, are used with this purpose because they increase extracellular dopamine level

Externí odkaz: https://doaj.org/article/8ecdad045b8549f5a0c7cfae4f16fa1c

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Cannabidiol prevents disruptions in sensorimotor gating induced by psychotomimetic drugs that last for 24-h with probable involvement of epigenetic changes in the ventral striatum

Autor: Francisco Silveira Guimarães, João Francisco Cordeiro Pedrazzi, Elaine Aparecida Del Bel, Amanda J. Sales, José Alexandre de Souza Crippa, Sâmia R.L. Joca

Publikováno v: Pedrazzi, J F C, Sales, A J, Guimarães, F S, Joca, S R L, Crippa, J A S & Del Bel, E 2021, ' Cannabidiol prevents disruptions in sensorimotor gating induced by psychotomimetic drugs that last for 24-h with probable involvement of epigenetic changes in the ventral striatum ', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 111, 110352 . https://doi.org/10.1016/j.pnpbp.2021.110352
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Cannabidiol (CBD), a major non-psychotomimetic component of the Cannabis sativa plant, shows therapeutic potential in several psychiatric disorders, including schizophrenia. The molecular mechanisms underlying the antipsychotic-like effects of CBD ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ff34e6e4b241c9d07f72ea765678f3
https://pure.au.dk/portal/da/publications/cannabidiol-prevents-disruptions-in-sensorimotor-gating-induced-by-psychotomimetic-drugs-that-last-for-24h-with-probable-involvement-of-epigenetic-changes-in-the-ventral-striatum(a6170968-f27c-4d85-94ab-55cc8715af5a).html

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The Chemically-Modified Tetracycline COL-3 and Its Parent Compound Doxycycline Prevent Microglial Inflammatory Responses by Reducing Glucose-Mediated Oxidative Stress

Autor: Nour Francis, Rosana Chehín, Bruno Figadère, Rita Raisman-Vozari, Paola Ramirez, Florencia González-Lizárraga, Paula Martorell, Patrick P. Michel, Nilson Carlos Ferreira Junior, Maurício dos Santos Pereira, Elaine Aparecida Del Bel

Publikováno v: Cells
Volume 10
Issue 8
Cells, MDPI, 2021, 10 (8), pp.2163. ⟨10.3390/cells10082163⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cells, 2021, 10 (8), pp.2163. ⟨10.3390/cells10082163⟩
Cells, Vol 10, Iss 2163, p 2163 (2021)

We used mouse microglial cells in culture activated by lipopolysaccharide (LPS) or α-synuclein amyloid aggregates (αSa) to study the anti-inflammatory effects of COL-3, a tetracycline derivative without antimicrobial activity. Under LPS or αSa sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df4114fa384166095e5c57f2eb1940

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ESTUDO EXPERIMENTAL DOS EFEITOS NEUROTÓXICOS DA TERAPIA FOTODINÂMICA NA MEDULA ESPINHAL

Autor: Lisinéia Maria Zanardi, Fernando Lucas Primo, Antonio Claudio Tedesco, Herton Rodrigo Tavares Costa, Elaine Aparecida Del Bel Belluz Guimarães, Helton Luiz Aparecido Defino, C. A. Silva, Luciana Almeida Lopes

Publikováno v: Coluna/Columna, Vol 18, Iss 3, Pp 176-180
Coluna/Columna, Volume: 18, Issue: 3, Pages: 176-180, Published: 02 SEP 2019
Coluna/Columna v.18 n.3 2019
Coluna/Columna
Sociedade Brasileira de Coluna (SBCO)
instacron:SBCO
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Objective To evaluate the effects of photodynamic therapy (PDT) on the dura mater using the photosensitizers aluminum chloride phthalocyanine and methylene blue in in vivo assays. Methods Fifty-six male Wistar rats were divided into two groups; one s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959a96838d7d878e87641674525fe19c
https://doi.org/10.1590/s1808-185120191803214848

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The non-antibiotic tetracycline COL-3 prevents microglial inflammatory responses by reducing glucose-mediated oxidative stress

Autor: Maurício dos-Santos-Pereira, Elaine Aparecida Del Bel, R. Raisman-Vozari, Rosana Chehín, Paola Ramirez, Nilson Carlos Ferreira-Junior, Florencia González-Lizárraga, Nour Francis, Patrick P. Michel

Figure 6: The inhibitory effects of COL-3 on TNF-α release are reproduced by either reducing glucose metabolism or lowering NADPH oxidase activity . (A) Quantification of TNF-α levels in microglial cells exposed or not to LPS (10 ng/ml, 24-h) in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d3957cb19b77824d588f734ec89e2f7
https://doi.org/10.22541/au.162144021.19509352/v1

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Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Autor: Elaine Aparecida Del Bel, Diana F. Lázaro, Nicolas Bizat, Patrick P. Michel, Rosana Chehín, Valeria Parrales, Eftychia Vasili, Antonio Dominguez-Meijide, Tiago F. Outeiro, Annie Lannuzel, Stéphane Haik, Annekatrin König, R. Raisman-Vozari, Florencia González-Lizárraga

Publikováno v: Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 151, pp.105256. ⟨10.1016/j.nbd.2021.105256⟩
Neurobiology of Disease, Vol 151, Iss, Pp 105256-(2021)
Neurobiology of Disease, 2021, 151, pp.105256. ⟨10.1016/j.nbd.2021.105256⟩
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

International audience; Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders characterized by the misfolding and aggregation of alpha-synuclein (aSyn). Doxycycline, a tetracyclic antibiotic shows neuroprotectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04742017d14d77fe2b75dbda119fb1e0
https://hal.sorbonne-universite.fr/hal-03195956/file/1-s2.0-S096999612100005X-main.pdf

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