Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elaine A. Merrill"'
Autor:
M. Tyler Nelson, Mark R. Charbonneau, Heidi G. Coia, Mary J. Castillo, Corey Holt, Eric S. Greenwood, Peter J. Robinson, Elaine A. Merrill, David Lubkowicz, Camilla A. Mauzy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Engineered live bacteria could represent a new class of therapeutic treatment for human disease. Here, the authors use a human gut-on-a-chip microfluidics system to characterize an engineered live bacterial therapeutic, designed for the treatment of
Externí odkaz:
https://doaj.org/article/229bd7533d5f4591b5fea3903111b0fd
Autor:
M. Tyler Nelson, Heidi G. Coia, Corey Holt, Eric S. Greenwood, Latha Narayanan, Peter J. Robinson, Elaine A. Merrill, Vaughn Litteral, Michael S. Goodson, Roland J. Saldanha, Matthew W. Grogg, Camilla A. Mauzy
Publikováno v:
ACS Biomaterials Science & Engineering.
Synbiotics are a new class of live therapeutics employing engineered genetic circuits. The rapid adoption of genetic editing tools has catalyzed the expansion of possible synbiotics, exceeding traditional testing paradigms in terms of both throughput
Autor:
Elaine A. Merrill, Peter J Robinson, Camilla A Mauzy, Heidi G. Coia, Corey Holt, Eric S. Greenwood, Mark R. Charbonneau, Mary Castillo, David Lubkowicz, M. Tyler Nelson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Engineered bacteria (synthetic biotics) represent a new class of therapeutics that leverage the tools of synthetic biology. Translational testing strategies are required to predict synthetic biotic function in the human body. Gut-on-a-chip microfluid
Autor:
John C. Lipscomb, Kyung O. Yu, Deirdre A. Mahle, Peter J Robinson, Teresa R Sterner, Elaine A. Merrill, Jeffery M. Gearhart
Publikováno v:
Toxicokinetics and Risk Assessment ISBN: 9780429163746
Toxicokinetics and Risk Assessment
Toxicokinetics and Risk Assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af237e0a62606e83731c2978e16e778a
https://doi.org/10.1201/b14275-7
https://doi.org/10.1201/b14275-7
Autor:
Elaine A. Merrill, Peter J Robinson, David R. Mattie, Andrea Hoffmann, Mitchell L Meade, Teresa R Sterner
Laboratory studies in rats support the potential for jet fuel to promote noise induced hearing loss (NIHL). Occupational studies indicate that pilots, aircrew, and aircraft maintenance workers suffer higher rates of hearing loss. Jet fuel toxicity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f683333e0c16cb633062c965e8ef8d
https://doi.org/10.21236/ada626660
https://doi.org/10.21236/ada626660
Autor:
Jeffrey W. Fisher, Elaine A. Merrill, Annie M. Jarabek, Teresa R Sterner, Peter J Robinson, Rebecca A. Clewell, Jeffery M. Gearhart
Publikováno v:
Toxicological Sciences. 83:25-43
Detection of perchlorate (ClO4-) in several drinking water sources across the U.S. has lead to public concern over health effects from chronic low-level exposures. Perchlorate inhibits thyroid iodide (I-) uptake at the sodium (Na+)-iodide (I-) sympor
Autor:
Rebecca A. Clewell, Jeffery M. Gearhart, Peter J Robinson, Latha Narayanan, Elaine A. Merrill
Publikováno v:
International Journal of Toxicology. 23:17-23
Various published data sets that investigate the potential effect of exogenous perchlorate ( [Formula: see text]) on the uptake of iodide in the thyroid and subsequent changes in thyroid hormone levels are available. In order to best use the data tow
Autor:
Rebecca A. Clewell, Jeffery M. Gearhart, Teresa R Sterner, Kyung O. Yu, Deirdre A. Mahle, Elaine A. Merrill, Jeffrey W. Fisher
Publikováno v:
Toxicological Sciences. 74:416-436
Perchlorate (ClO4-), a contaminant in drinking water, competitively inhibits active uptake of iodide (I-) into various tissues, including mammary tissue. During postnatal development, inhibition of I- uptake in the mammary gland and neonatal thyroid
Autor:
Elaine A. Merrill, Kyung O. Yu, Teresa R Sterner, Rebecca A. Clewell, Jeffery M. Gearhart, Peter J Robinson, Jeffrey W. Fisher, David R. Mattie
Publikováno v:
Toxicological Sciences. 73:256-269
Due to perchlorate's (ClO4-) ability to competitively inhibit thyroid iodide (I-) uptake through the sodium-iodide symporter (NIS), potential human health risks exist from chronic exposure via drinking water. Such risks may include hypothyroidism, go
Publikováno v:
Health Physics. 74:568-573
Storage of radon-producing material in two silos and two waste pits is one of the major environmental and occupational issues at a former uranium production facility, now a Superfund site. In addition, up to 100 metric tons of thorium is stored on th