Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elaine, Emmerson"'
Autor:
Amanda L. Johnson, Sonia S. Elder, John G. McKendrick, Lizi M. Hegarty, Ella Mercer, Elaine Emmerson
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/60d13ab2802742ffa72c73d92bf0b925
Publikováno v:
Frontiers in Biomaterials Science, Vol 3 (2024)
Cancer affects tens of millions of the world’s population each year with a stark mortality rate. It is well established that in order to be effective in treating solid tumor cancers, the current treatment methods used often sacrifice surrounding he
Externí odkaz:
https://doaj.org/article/aeedc131ef9a4981961085d2f627060b
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: Increased cancer rates denote that one in two people will be diagnosed with cancer in their lifetime. Over 60% of cancer patients receive radiotherapy, either as a stand-alone treatment or in combination with other treatments such as chem
Externí odkaz:
https://doaj.org/article/78971ef9cd0b400a9904b60eb9b539d3
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Primary hypothyroidism severely impacts the quality of life of patients through a decrease in the production of the thyroid hormones T3 and T4, leading to symptoms affecting cardiovascular, neurological, cognitive, and metabolic function. The inciden
Externí odkaz:
https://doaj.org/article/613273d800cd4262a8b7f524671437e0
Autor:
Sonia S. Elder, Elaine Emmerson
Publikováno v:
Open Biology, Vol 10, Iss 12 (2020)
Over the last decade, our understanding of the physiological role of senescent cells has drastically evolved, from merely indicators of cellular stress and ageing to having a central role in regeneration and repair. Increasingly, studies have identif
Externí odkaz:
https://doaj.org/article/0504bf080a0b43e1b336c84a057e494f
Autor:
Elaine Emmerson, Alison J May, Lionel Berthoin, Noel Cruz‐Pacheco, Sara Nathan, Aaron J Mattingly, Jolie L Chang, William R Ryan, Aaron D Tward, Sarah M Knox
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-18 (2018)
Abstract Salivary gland acinar cells are routinely destroyed during radiation treatment for head and neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential regenerative strategy for replacing injured tissue is the
Externí odkaz:
https://doaj.org/article/4176d4197b9e49dfbb2cac3c79cfc025
Autor:
Padma Priya Togarrati, Robson T. Sasaki, Mohamed Abdel-Mohsen, Nuntana Dinglasan, Xutao Deng, Shivani Desai, Elaine Emmerson, Elizabeth Yee, William R. Ryan, Marcelo C. P. da Silva, Sarah M. Knox, Satish K. Pillai, Marcus O. Muench
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Mesenchymal stem/stromal cells (MSCs) play crucial roles in maintaining tissue homeostasis during physiological turnovers and injuries. Very little is known about the phenotype, distribution and molecular nature of MSCs in freshly isolated h
Externí odkaz:
https://doaj.org/article/946eacca463c4f2faa7a80d9398bf5ae
Autor:
Elaine Emmerson, Alison J May, Sara Nathan, Noel Cruz-Pacheco, Carlos O Lizama, Lenka Maliskova, Ann C Zovein, Yin Shen, Marcus O Muench, Sarah M Knox
Publikováno v:
eLife, Vol 6 (2017)
Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gla
Externí odkaz:
https://doaj.org/article/9d3b35d7cb0c435c8c036252dd89ae39
Autor:
John G. McKendrick, Gareth-Rhys Jones, Sonia S. Elder, Ella Mercer, Marlene S. Magalhaes, Cecilia Rocchi, Lizi M. Hegarty, Amanda L. Johnson, Christoph Schneider, Burkhard Becher, Clare Pridans, Neil Mabbott, Zhaoyuan Liu, Florent Ginhoux, Marc Bajenoff, Rebecca Gentek, Calum C. Bain, Elaine Emmerson
The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in xerostomia, or chronic dry mouth. This leads to detrimental effects on their health and quality of life, for which there is no regen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f4535b51b09e73c3110ed64f3d6510
https://doi.org/10.1101/2022.06.12.495803
https://doi.org/10.1101/2022.06.12.495803
Autor:
John G, McKendrick, Elaine, Emmerson
Publikováno v:
International review of cell and molecular biology. 368
Macrophages are mononuclear innate immune cells which have become of increasing interest in the fields of disease and regeneration, as their non-classical functions have been elucidated in addition to their classical inflammatory functions. Macrophag