Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Elaine, Delvaux"'
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1592 (2022)
The clinical diagnosis of neurodegenerative diseases is notoriously inaccurate and current methods are often expensive, time-consuming, or invasive. Simple inexpensive and noninvasive methods of diagnosis could provide valuable support for clinicians
Externí odkaz:
https://doaj.org/article/03d2664e562f4da8acf4bc300639fdde
Autor:
Ignazio S. Piras, Danielle Brokaw, Yinfei Kong, Daniel J. Weisenberger, Jonida Krate, Elaine Delvaux, Swapna Mahurkar, Adam Blattler, Kimberly D. Siegmund, Lucia Sue, Geidy E. Serrano, Thomas G. Beach, Peter W. Laird, Matthew J. Huentelman, Paul D. Coleman
Publikováno v:
Cellular and Molecular Neurobiology.
Alzheimer’s disease is a neurodegenerative disorder clinically defined by gradual cognitive impairment and alteration in executive function. We conducted an epigenome-wide association study (EWAS) of a clinically and neuropathologically characteriz
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191382 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0177814.].
Externí odkaz:
https://doaj.org/article/ef111e1b74364a4b8b41c00f6cf51a26
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Dysfunctional processes in Alzheimer's disease and other neurodegenerative diseases lead to neural degeneration in the central and peripheral nervous system. Research demonstrates that neurodegeneration of any kind is a systemic disease that may even
Autor:
Diego Mastroeni, Shobana Sekar, Jennifer Nolz, Elaine Delvaux, Katie Lunnon, Jonathan Mill, Winnie S Liang, Paul D Coleman
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0177814 (2017)
Recent epigenetic association studies have identified a new gene, ANK1, in the pathogenesis of Alzheimer's disease (AD). Although strong associations were observed, brain homogenates were used to generate the data, introducing complications because o
Externí odkaz:
https://doaj.org/article/f4fbb189ce6a48aa8835a0d7476623c4
Autor:
Ignazio S, Piras, Danielle, Brokaw, Yinfei, Kong, Daniel J, Weisenberger, Jonida, Krate, Elaine, Delvaux, Swapna, Mahurkar, Adam, Blattler, Kimberly D, Siegmund, Lucia, Sue, Geidy E, Serrano, Thomas G, Beach, Peter W, Laird, Matthew J, Huentelman, Paul D, Coleman
Publikováno v:
Cellular and molecular neurobiology.
Alzheimer's disease is a neurodegenerative disorder clinically defined by gradual cognitive impairment and alteration in executive function. We conducted an epigenome-wide association study (EWAS) of a clinically and neuropathologically characterized
Autor:
Danielle Brokaw, Thomas G. Beach, Geidy E. Serrano, Diego Mastroeni, Matthew J. Huentelman, Ignazio S. Piras, Jennifer Nolz, Paul D. Coleman, Daniel J. Weisenberger, Elaine Delvaux
Publikováno v:
Neurobiol Aging
Whether a cell lives or dies is controlled by an array of intercepting and dynamic molecular pathways. Although there is evidence of neuronal loss in Alzheimer’s disease (AD) and multiple programmed cell death (PCD) pathways have been implicated in
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Ignazio S. Piras, Jonida Krate, Diego Mastroeni, Matthew De Both, Matthew J. Huentelman, Jennifer Nolz, Geidy E. Serrano, Elaine Delvaux, Lucia I. Sue, Thomas G. Beach, Paul D. Coleman
Publikováno v:
Brain Research. 1719:217-224
We explored RNA expression changes in the middle temporal gyrus (MTG) of Alzheimer's Disease patients (AD) by RNA sequencing the whole transcriptome of 8 AD and 8 Non-Demented (ND) controls. We used three additional expression datasets from related b
Autor:
Tim Vanmierlo, Katie Lunnon, Dean Paes, Diego Mastroeni, Janou A. Y. Roubroeks, Daniel L.A. van den Hove, Ehsan Pishva, Elaine Delvaux, Paul D. Coleman, Roy Lardenoije, Melissa Schepers, Riccardo M. Carollo, Jos Prickaerts
Publikováno v:
Neurobiology of Aging, 97, 56-64. Elsevier Science
Pharmacological phosphodiesterase 4D (PDE4D) inhibition shows therapeutic potential to restore memory function in Alzheimer's disease (AD), but will likely evoke adverse side effects. As PDE4D encodes multiple isoforms, targeting specific isoforms ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5700354515d40386a8c31e7384e6587
http://hdl.handle.net/1942/33241
http://hdl.handle.net/1942/33241