Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Elai, Davicioni"'
Autor:
Min Woo Hwang, Jasmine Kauffeld, Sarah Belay, Joep J. de Jong, Elai Davicioni, Wenping Li, Jeanny B. Aragon-Ching
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 6, Pp 1061-1070 (2024)
Upper tract urothelial cancer (UTUC) are rare subsets of urothelial cancer, which typically present with more aggressive course. Molecular markers stratifying urothelial tumors as luminal subtype and non-luminal subtype tumors have been proposed to s
Externí odkaz:
https://doaj.org/article/737cc26d5a614b3e97fe1575ba608ead
Autor:
Jon Griffin, Jenny Down, Lewis A Quayle, Paul R Heath, Ewan A Gibb, Elai Davicioni, Yang Liu, Xin Zhao, Jayne Swain, Dennis Wang, Syed Hussain, Simon Crabb, James WF Catto, the GUSTO Trial Management Group
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract The GUSTO clinical trial (Gene expression subtypes of Urothelial carcinoma: Stratified Treatment and Oncological outcomes) uses molecular subtypes to guide neoadjuvant therapies in participants with muscle‐invasive bladder cancer (MIBC). B
Externí odkaz:
https://doaj.org/article/4fef0e3838804e81a865003240a3ce8e
Autor:
Melvin L. K. Chua, Alexander K. Hakansson, Enya H. W. Ong, Boon Hao Hong, Jing Jing Miao, Adelene Y. L. Sim, Janice S. H. Tan, Kah Min Tan, Gabrielle C. J. Lee, Kar Perng Low, Jeffrey K. L. Tuan, Terence W. K. Tan, Michael L. C. Wang, Joe P. S. Yeong, Michael C. S. Tan, Lui Shiong Lee, Ravindran Kanesvaran, Xin Zhao, Julian Ho, Daniel E. Spratt, Edward M. Schaeffer, Kae‐Jack Tay, Yang Liu, Elai Davicioni, Li Yan Khor
Publikováno v:
Cancer Communications, Vol 43, Iss 10, Pp 1164-1168 (2023)
Externí odkaz:
https://doaj.org/article/2820ad25f44944e88127d04999d57ac3
Autor:
Neal Patel, Alexander Hakansson, Shinji Ohtake, Peter Muraki, James A. Proudfout, Yang Liu, Lisa Webber, Arkaitz Ibarra, Vinnie Y. T. Liu, Elai Davicioni, Karim Chamie, Allan Pantuck, Brian Shuch
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6437-6444 (2023)
Abstract Background Risk stratification of kidney cancer patients after nephrectomy may tailor surveillance intensity and selection for adjuvant therapy. Transcriptomic approaches are effective in predicting recurrence, but whether they add value to
Externí odkaz:
https://doaj.org/article/bd78f3f34c2c414f9cd6de33e881a5f4
Autor:
Ashwin Ramaswamy, James A. Proudfoot, Ashley E. Ross, Elai Davicioni, Edward M. Schaeffer, Jim C. Hu
Publikováno v:
European Urology Open Science, Vol 48, Iss , Pp 90-97 (2023)
Background: Despite the historic association of higher prostate cancer volume with worse oncologic outcomes, little is known about the impact of tumor volume on cancer biology. Objective: To characterize the relationship between tumor volume (measure
Externí odkaz:
https://doaj.org/article/2e435c7f25614f6391f7bf130e3d775c
Autor:
Yang Liu, Katharina Lueckerath, Jason Hughes, Wolfgang Peter Fendler, Ken Herrmann, Alexander Hakansson, Analena Handke, Claudia Kesch, Tugce Telli, Elai Davicioni, Hong Song, Boris Hadaschik, Robert Seifert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Rationale 177Lu-PSMA ([177Lu]Lutetium-PSMA-617) therapy is an effective treatment option for patients with prostate specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer, but still shows a non-responder rate of app
Externí odkaz:
https://doaj.org/article/b6e2f176f67a4c6e8b5ba00ed2930544
Autor:
Yuki Yoshikawa, Konrad H. Stopsack, Xin Victoria Wang, Yu‐Hui Chen, Ying Z. Mazzu, Foster Burton, Goutam Chakraborty, Sai Harisha Rajanala, Rahim Hirani, Subhiksha Nandakumar, Gwo‐Shu Mary Lee, David Frank, Elai Davicioni, Glenn Liu, Michael A. Carducci, Haruhito Azuma, Philip W. Kantoff, Christopher J. Sweeney
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3994-4010 (2022)
Loss of the histone demethylase KDM5D (lysine‐specific demethylase 5D) leads to in vitro resistance of prostate cancer cells to androgen deprivation therapy (ADT) with and without docetaxel. We aimed to define downstream drivers of the KDM5D effect
Externí odkaz:
https://doaj.org/article/f3e5c6df0fe14e4b96ddc7e70c0635e6
Autor:
Kevin H. Kensler, Shivanshu Awasthi, Mohamed Alshalalfa, Bruce J. Trock, Stephen J. Freedland, Michael R. Freeman, Sungyong You, Brandon A. Mahal, Robert B. Den, Adam P. Dicker, R. Jeffrey Karnes, Eric A. Klein, Priti Lal, Yang Liu, Elai Davicioni, Walter Rayford, Kosj Yamoah, Timothy R. Rebbeck
Publikováno v:
European Urology Open Science, Vol 40, Iss , Pp 19-26 (2022)
Background: Socioeconomic and health care utilization factors are major drivers of prostate cancer (PC) mortality disparities in the USA; however, tumor molecular heterogeneity may also contribute to the higher mortality among Black men. Objective: T
Externí odkaz:
https://doaj.org/article/0f6271a5f96f4db29f8e1ec6aede759a
Autor:
Xintao Qiu, Nadia Boufaied, Tarek Hallal, Avery Feit, Anna de Polo, Adrienne M. Luoma, Walaa Alahmadi, Janie Larocque, Giorgia Zadra, Yingtian Xie, Shengqing Gu, Qin Tang, Yi Zhang, Sudeepa Syamala, Ji-Heui Seo, Connor Bell, Edward O’Connor, Yang Liu, Edward M. Schaeffer, R. Jeffrey Karnes, Sheila Weinmann, Elai Davicioni, Colm Morrissey, Paloma Cejas, Leigh Ellis, Massimo Loda, Kai W. Wucherpfennig, Mark M. Pomerantz, Daniel E. Spratt, Eva Corey, Matthew L. Freedman, X. Shirley Liu, Myles Brown, Henry W. Long, David P. Labbé
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The role of MYC in transcriptional reprogramming in prostate cancer remains poorly characterized. Here, MYC overexpression antagonizes the canonical AR transcriptional program leading to prostate tumor initiation and progression by disrupting transcr
Externí odkaz:
https://doaj.org/article/bc90d144fd374a6387fda7079a332f9f
Autor:
Neha Singh, Varune R. Ramnarine, Jin H. Song, Ritu Pandey, Sathish K. R. Padi, Mannan Nouri, Virginie Olive, Maxim Kobelev, Koichi Okumura, David McCarthy, Michelle M. Hanna, Piali Mukherjee, Belinda Sun, Benjamin R. Lee, J. Brandon Parker, Debabrata Chakravarti, Noel A. Warfel, Muhan Zhou, Jeremiah J. Bearss, Ewan A. Gibb, Mohammed Alshalalfa, R. Jefferey Karnes, Eric J. Small, Rahul Aggarwal, Felix Feng, Yuzhuo Wang, Ralph Buttyan, Amina Zoubeidi, Mark Rubin, Martin Gleave, Frank J. Slack, Elai Davicioni, Himisha Beltran, Colin Collins, Andrew S. Kraft
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Elevated expression of long noncoding RNA H19 is seen in clinical samples of neuroendocrine prostate cancer (PCa). Here the authors show H19 promotes plasticity from luminal to neuroendocrine by epigenetic reprogramming.
Externí odkaz:
https://doaj.org/article/fe3ffb322dcb47a8b750da286a3e5ab2