Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Elahe Mahdavian"'
Autor:
Natalie Carroll, Reneau Youngblood, Alena Smith, Ana-Maria Dragoi, Brian A. Salvatore, Elahe Mahdavian
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2906 (2022)
Fusarochromanone is an experimental drug with unique and potent anti-cancer activity. Current cancer therapies often incorporate a combination of drugs to increase efficacy and decrease the development of drug resistance. In this study, we used drug
Externí odkaz:
https://doaj.org/article/4837b7f55379409191f278a714a51db4
Autor:
Shokoufeh Hashempour, Nahid Shahabadi, Aishat Adewoye, Brennen Murphy, Camaray Rouse, Brian A. Salvatore, Christopher Stratton, Elahe Mahdavian
Publikováno v:
Molecules, Vol 25, Iss 22, p 5410 (2020)
The interactions of small molecule drugs with plasma serum albumin are important because of the influence of such interactions on the pharmacokinetics of these therapeutic agents. 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) is one such drug
Externí odkaz:
https://doaj.org/article/5e21e7f722154ddeba878b1f4cbb39f8
Autor:
Ying Gu, Xin Chen, Chaowei Shang, Karnika Singh, Mansoureh Barzegar, Elahe Mahdavian, Brian A Salvatore, Shanxiang Jiang, Shile Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112641 (2014)
Fusarochromanone (FC101), a mycotoxin produced by the fungus Fusarium equiseti, is frequently observed in the contaminated grains and feedstuffs, which is toxic to animals and humans. However, the underlying molecular mechanism remains to be defined.
Externí odkaz:
https://doaj.org/article/cc1e4fee322c4f01b5ab49c93e0edf89
Supplementary Figure from YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1757634f8a5b5adfdd134b5d99d6aa2c
https://doi.org/10.1158/1535-7163.22521934.v1
https://doi.org/10.1158/1535-7163.22521934.v1
Anaplastic thyroid cancer (ATC) is among the most aggressive of human cancers, and currently there are few effective treatments for most patients. YM155, first identified as a survivin inhibitor, was highlighted in a high-throughput screen performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5479eba842c041d8de20360f5271bd
https://doi.org/10.1158/1535-7163.c.6543229
https://doi.org/10.1158/1535-7163.c.6543229
Publikováno v:
Mol Cancer Ther
Anaplastic thyroid cancer is among the most aggressive of human cancers, and currently there are few effective treatments for most patients. YM155, first identified as a survivin inhibitor, was highlighted in a high-throughput screen performed by the
Publikováno v:
Tissuecell. 80
Exosomes (EXOs) are extracellular vesicles derived from the endosome. These heterogeneous nanoparticles (30-150 nm) are secreted from various cells and play important biological roles in intercellular communication. EXOs have received much attention
Publikováno v:
سلامت و محیط, Vol 13, Iss 2, Pp 365-384 (2020)
Background and Objective: Global market growth of reverse osmosis (RO) has led to an increase in annual disposal of membrane wastes. Therefore, evaluation of membrane waste management strategies is important to reduce their adverse environmental impa
Autor:
Abbas Amer Ridha, Hossein Zhaleh, Ronak Rafipour, Abbas Hemati Azandaryani, Soheila Kashanian, Elahe Mahdavian
Publikováno v:
Pharmaceutical development and technology. 26(6)
Various nano-sized protein and lipid complexes are being investigated as drug delivery systems. The encapsulation of more than one drug in a single nanocomplex carrier could enhance the therapeutic potency and afford synergistic therapeutic effects.
Background: Fusarochromanone (FC101) is a small molecule with potent anti-cancer activity. It was originally derived from the fungal plant pathogen, Fusarium equiseti, and it has also been synthesized in non-racemic form in our lab. Numerous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130a82adc7473402644314f0363066ff
https://doi.org/10.21203/rs.3.rs-289662/v1
https://doi.org/10.21203/rs.3.rs-289662/v1