Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Eladio J. Márquez"'
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract While Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is disrupting lives across the globe for everyone, it has a more devastating impact on the health of older adults, especially
Externí odkaz:
https://doaj.org/article/4767aa291ec64a02bde80823004492bd
Autor:
Eladio J. Márquez, Cheng-han Chung, Radu Marches, Robert J. Rossi, Djamel Nehar-Belaid, Alper Eroglu, David J. Mellert, George A. Kuchel, Jacques Banchereau, Duygu Ucar
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as wel
Externí odkaz:
https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
Autor:
Katie Pelletier, William R Pitchers, Anna Mammel, Emmalee Northrop-Albrecht, Eladio J Márquez, Rosa A Moscarella, David Houle, Ian Dworkin
Publikováno v:
GENETICS.
Identifying the genetic architecture of complex traits is important to many geneticists, including those interested in human disease, plant and animal breeding, and evolutionary genetics. Advances in sequencing technology and statistical methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::660ef7797236abb9264b69edf16387d4
https://doi.org/10.1093/genetics/iyad050
https://doi.org/10.1093/genetics/iyad050
Autor:
Katie Pelletier, William R. Pitchers, Anna Mammel, Emmalee Northrop-Albrecht, Eladio J. Márquez, Rosa A. Moscarella, David Houle, Ian Dworkin
Identifying the genetic architecture of complex traits is important to many geneticists, including those interested in human disease, plant and animal breeding, and evolutionary genetics. Advances in sequencing technology and statistical methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::570314bc9b973740ae911201e99bb69c
https://doi.org/10.1101/2022.05.12.491649
https://doi.org/10.1101/2022.05.12.491649
Autor:
Asa Thibodeau, Eladio J Márquez, Oscar Luo, Yijun Ruan, Francesca Menghi, Dong-Guk Shin, Michael L Stitzel, Paola Vera-Licona, Duygu Ucar
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 6, p e1004809 (2016)
UnlabelledRecent studies of the human genome have indicated that regulatory elements (e.g. promoters and enhancers) at distal genomic locations can interact with each other via chromatin folding and affect gene expression levels. Genomic technologies
Externí odkaz:
https://doaj.org/article/bf5a8b5f969148eba9f21a6154f0656b
Autor:
Djamel Nehar-Belaid, Jacques Banchereau, Alper Eroglu, Duygu Ucar, David J. Mellert, Robert J. Rossi, Eladio J. Márquez, Radu Marches, George A. Kuchel, Cheng-han Chung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Differences in immune function and responses contribute to health- and life-span disparities between sexes. However, the role of sex in immune system aging is not well understood. Here, we characterize peripheral blood mononuclear cells from 172 heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fb43a1ec0a48b4f209fcd294bec501
https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
Autor:
Mihaela Aldea, Angelique Biancotto, Eric Angevin, Jean-Yves Scoazec, Marielle Chiron, Etienne Rouleau, Dib Colette, Shu Yan, Joon Sang Lee, Jack Pollard, Ludovic Lacroix, Nathalie Chaput-Gras, Saloomeh Rafie, Benjamin Besse, Eladio J. Márquez, F. Blanc-Durand, David Planchard, Aurélien Marabelle, Cecile Combeau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundReinvigoration of anti-tumor immunity via immune checkpoint blockade (ICB) has transformed outcomes in a-NSCLC. However, a majority of patients are innately resistant to ICB, and a better understanding of the resistance mechanisms may guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7c0005a7bdb74b0ba5ec08fa23c685
https://doaj.org/article/eec93b5ed5454a5b9e6ce5c07f948486
https://doaj.org/article/eec93b5ed5454a5b9e6ce5c07f948486
Publikováno v:
Bioinformatics
Summary Single-cell RNA-sequencing (scRNA-seq) technology enables studying gene expression programs from individual cells. However, these data are subject to diverse sources of variation, including ‘unwanted’ variation that needs to be removed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892dc062163dc7f9f840d04757ca6c39
https://doi.org/10.1093/bioinformatics/btaa128
https://doi.org/10.1093/bioinformatics/btaa128
Autor:
Hui Cao, Kerstin A. Heyl, Tatiana Tolstykh, Hui Qu, Marie Bernardo, Timothy R. Wagenaar, Kuldeep Singh, Katie Malley, Emma Wang, Errin Roberts, Yu-an Zhang, Fangxian Sun, Jack Pollard, Sue Ryan, Dinesh S. Bangari, Eladio J. Márquez, Dmitri Wiederschain, Joon Sang Lee, Keith Bahjat, Natalia Malkova
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Immune checkpoint blockade elicits durable anti-cancer responses in the clinic, however a large proportion of patients do not benefit from treatment. Several mechanisms of innate and acquired resistance to checkpoint blockade have been defined and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b34c1a8482c6fae0555152ffe610c3
https://doi.org/10.1080/2162402x.2021.1881268
https://doi.org/10.1080/2162402x.2021.1881268
Publikováno v:
Immunity & Ageing : I & A
Immunity & ageing, 17(1):13
Immunity & Ageing, Vol 17, Iss 1, Pp 1-8 (2020)
Immunity & ageing, 17(1):13
Immunity & Ageing, Vol 17, Iss 1, Pp 1-8 (2020)
While Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is disrupting lives across the globe for everyone, it has a more devastating impact on the health of older adults, especially that of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a86da369169230e16ff9a239322ae9a
http://europepmc.org/articles/PMC7240166
http://europepmc.org/articles/PMC7240166