Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eladio Flores Sanchez"'
Autor:
Camila Castro-Pinheiro, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Ana Cláudia Rodrigues da Silva, Corinna A. Dwan, Samuel S. Karpiniec, Alan Trevor Critchley, Andre Lopes Fuly
Publikováno v:
Toxins, Vol 16, Iss 4, p 188 (2024)
Background: Snakebite envenomation (SBE) causes diverse toxic effects in humans, including disability and death. Current antivenom therapies effectively prevent death but fail to block local tissue damage, leading to an increase in the severity of en
Externí odkaz:
https://doaj.org/article/779b18dc1a044a6cb5587eb1cb985c7d
Autor:
Nayanna de Mello Amorim, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Gabriel Alves de Aquino, Vitor Francisco Ferreira, Sabrina Baptista Ferreira, André Lopes Fuly, Eduardo Coriolano de Oliveira
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2023)
Abstract Snake envenomation is a public health problem, and while serum therapy prevents death, the local effects of venoms can lead to amputations or morbidities. Thus, alternative treatments deserve attention. In this study, we tested eight derivat
Externí odkaz:
https://doaj.org/article/d10c74758be440cd83e31ad05407689e
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies. Emergent e
Externí odkaz:
https://doaj.org/article/6dba963cdccf4777ae15048caf9d8cfc
Autor:
Dan E. Vivas-Ruiz, Paola Rosas, Alex Proleón, Daniel Torrejón, Fanny Lazo, Ana Belén Tenorio-Ricca, Francisco Guajardo, Cristopher Almarza, Víctor Andrades, Jessica Astorga, Daniel Oropesa, Jorge Toledo, María Jesús Vera, Jorge Martínez, Ramiro Araya-Maturana, Karen Dubois-Camacho, Marcela A. Hermoso, Valéria G. Alvarenga, Eladio Flores Sanchez, Armando Yarlequé, Luciana Souza Oliveira, Félix A. Urra
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1533 (2023)
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration. In this work, we characterize a novel P-III class snake venom metalloproteinas
Externí odkaz:
https://doaj.org/article/43eed5d3f77f43fea778f614b04bc86b
Autor:
Jenifer Frouche de Souza, Eduardo Coriolano de Oliveira, Ana Cláudia Rodrigues da Silva, Vagner Pereira da Silva, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112285- (2021)
Externí odkaz:
https://doaj.org/article/52b90bba9c104314955365e9898d0d7d
Autor:
Jenifer Frouche de Souza, Eduardo Coriolano de Oliveira, Ana Cláudia Rodrigues da Silva, Vagner Pereira da Silva, Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109951- (2020)
Envenomation by snakes is a worldwide health public issue, and antivenoms are less efficient in neutralizing local toxic effects. Thus, more efficient therapies to treat patients deserve attention, and plants have been extensively tested. So, the aim
Externí odkaz:
https://doaj.org/article/12d10fbe99d143c098f362f66aa9b510
Autor:
Eladio Flores Sanchez, Michael Richardson, Luiza Helena Gremski, Silvio Sanches Veiga, Armando Yarleque, Stephan Niland, Augusto Martins Lima, Maria Inácia Estevao-Costa, Johannes Andreas Eble
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1609-1613 (2016)
Initial association of platelets after vascular injury is mediated by glycoprotein (GP)Ib-IX-V binding to von Willebrand factor (vWf) immobilized on exposed collagens and eventually leads to thrombus formation. This article provides data about a new
Externí odkaz:
https://doaj.org/article/b3dbf59a14064e1ca31770b7fa7c03e4
Autor:
Ana Cláudia Rodrigues da Silva, Luciana Garcia Ferreira, Maria Eugênia Rabello Duarte, Miguel Daniel Noseda, Eladio Flores Sanchez, André Lopes Fuly
Publikováno v:
Marine Drugs, Vol 13, Iss 6, Pp 3761-3775 (2015)
In Brazil, snakebites are a public health problem and accidents caused by Lachesis muta have the highest mortality index. Envenomation by L. muta is characterized by systemic (hypotension, bleeding and renal failure) and local effects (necrosis, pain
Externí odkaz:
https://doaj.org/article/2926c7972ae84535a7307b6ffe98a477
Autor:
Ana Cláudia Rodrigues da Silva, Maria Eugenia Rabello Duarte, Miguel Daniel Noseda, Luciana Garcia Ferreira, Juliana Emanuela Fogari Cassolato, Eladio Flores Sanchez, Andre Lopes Fuly
Publikováno v:
Marine Drugs, Vol 16, Iss 11, p 412 (2018)
Worldwide, snakebites have serious implications for human health. The administration of antivenom is the official treatment used to reverse the toxic activities of envenomation. However, this therapy is not efficient to treat the local effects, leadi
Externí odkaz:
https://doaj.org/article/fcf0b0e1c17049d6bca9744232d2d0c9
Autor:
Geisiane Alves da Silva, Thaisa Francielle Souza Domingos, Rainiomar Raimundo Fonseca, Eladio Flores Sanchez, Valéria Laneuville Teixeira, André Lopes Fuly
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 21, Iss 0 (2015)
Background Snakebite is considered a neglected tropical disease by the World Health Organization. In Brazil, about 70% of the envenomation cases are caused by Bothrops snakes. Its venom may provoke hemorrhage, pain, necrosis, hemolysis, renal or card
Externí odkaz:
https://doaj.org/article/500d380ae1a949459a419fb6880accde