Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Elad L. Laviad"'
Autor:
Sandra N. Pinto, Elad L. Laviad, Johnny Stiban, Samuel L. Kelly, Alfred H. Merrill, Jr., Manuel Prieto, Anthony H. Futerman, Liana C. Silva
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 1, Pp 53-61 (2014)
Ceramide (Cer) is involved in the regulation of several cellular processes by mechanisms that depend on Cer-induced changes on membrane biophysical properties. Accumulating evidence shows that Cers with different N-acyl chain composition differential
Externí odkaz:
https://doaj.org/article/8cac9f22bb484f81b79a079ebbd60a36
Autor:
Liana C. Silva, Oshrit Ben David, Yael Pewzner-Jung, Elad L. Laviad, Johnny Stiban, Sibali Bandyopadhyay, Alfred H. Merrill, Jr., Manuel Prieto, Anthony H. Futerman
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 3, Pp 430-436 (2012)
Little is known about the effects of altering sphingolipid (SL) acyl chain structure and composition on the biophysical properties of biological membranes. We explored the biophysical consequences of depleting very long acyl chain (VLC) SLs in membra
Externí odkaz:
https://doaj.org/article/6b651edc6406450e94b24957ececdfd4
Autor:
Irina Petrache, Krzysztof Kamocki, Christophe Poirier, Yael Pewzner-Jung, Elad L Laviad, Kelly S Schweitzer, Mary Van Demark, Matthew J Justice, Walter C Hubbard, Anthony H Futerman
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62968 (2013)
Increases in ceramide levels have been implicated in the pathogenesis of both acute or chronic lung injury models. However, the role of individual ceramide species, or of the enzymes that are responsible for their synthesis, in lung health and diseas
Externí odkaz:
https://doaj.org/article/34e170a9c540460bb459a106214234dc
Autor:
Liana C. Silva, Anthony H. Futerman, Manuel Prieto, Alfred H. Merrill, Samuel Kelly, Elad L. Laviad, Sandra N. Pinto, Johnny Stiban
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 1, Pp 53-61 (2014)
Ceramide (Cer) is involved in the regulation of several cellular processes by mechanisms that depend on Cer-induced changes on membrane biophysical properties. Accumulating evidence shows that Cers with different N-acyl chain composition differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3909b07412b4352e60eed974ad00a986
https://doi.org/10.1194/jlr.m042002
https://doi.org/10.1194/jlr.m042002
Publikováno v:
Molecular Nutrition & Food Research. 57:516-522
Scope Fumonisins are mycotoxins produced by Fusarium species. The predominant derivative, fumonisin B1 (FB1), occurs in food and feed and is of health concern due to its hepatotoxic and carcinogenic effects. However, the role of FB1 metabolites on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d3ff5b4f0371d5b0abd36c51f5c0ae
https://doi.org/10.1002/mnfr.201200465
https://doi.org/10.1002/mnfr.201200465
Autor:
Hiroyuki Osada, Michel Lagarde, Shota Sakai, Peter Greimel, Nario Tomishige, Françoise Hullin-Matsuda, Hubert Vidal, Anthony H. Futerman, Kumiko Ishii, Elad L. Laviad, Reiko Ishitsuka, Mitsuhiro Abe, Kentaro Hanada, Asami Makino, Tamio Saito, Toshihide Kobayashi
Publikováno v:
Journal of Biological Chemistry. 287:24397-24411
To identify novel inhibitors of sphingomyelin (SM) metabolism, a new and selective high throughput microscopy-based screening based on the toxicity of the SM-specific toxin, lysenin, was developed. Out of a library of 2011 natural compounds, the limo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edc5b8b7d4c517237f0f12f64d71ce4
https://doi.org/10.1074/jbc.m112.344432
https://doi.org/10.1074/jbc.m112.344432
Publikováno v:
Journal of Biological Chemistry. 287:21025-21033
Ceramide, the backbone of all sphingolipids, is synthesized by a family of ceramide synthases (CerS) that each use acyl-CoAs of defined chain length for N-acylation of the sphingoid long chain base. CerS mRNA expression and enzymatic activity do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e506d3d4c6839a0ec3fa7e61176cfbf8
https://doi.org/10.1074/jbc.m112.363580
https://doi.org/10.1074/jbc.m112.363580
Autor:
Elad L. Laviad, Alfred H. Merrill, Johnny Stiban, Anthony H. Futerman, Manuel Prieto, Liana C. Silva, Yael Pewzner-Jung, Sibali Bandyopadhyay, Oshrit Ben David
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 3, Pp 430-436 (2012)
Little is known about the effects of altering sphingolipid (SL) acyl chain structure and composition on the biophysical properties of biological membranes. We explored the biophysical consequences of depleting very long acyl chain (VLC) SLs in membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9b41f3d087b3d7c16028c2f557a7de
http://www.sciencedirect.com/science/article/pii/S0022227520413586
http://www.sciencedirect.com/science/article/pii/S0022227520413586
Autor:
Anthony H. Futerman, Elad L. Laviad, Liana C. Silva, Yael Pewzner-Jung, Britta Brügger, Hyejung Park, Timo Sachsenheimer, Sujoy Lahiri, Racheli Erez-Roman, Johnny Stiban, Felix T. Wieland, Alfred H. Merrill, Manuel Prieto
Publikováno v:
Journal of Biological Chemistry. 285:10902-10910
Ceramide is an important lipid signaling molecule that plays critical roles in regulating cell behavior. Ceramide synthesis is surprisingly complex and is orchestrated by six mammalian ceramide synthases, each of which produces ceramides with restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c420ffe79ee64472666b076b3d6c3e
https://doi.org/10.1074/jbc.m109.077594
https://doi.org/10.1074/jbc.m109.077594
Autor:
Yael Pewzner-Jung, Abraham Nyska, Calanit Raanan, Dorin Holzman, Tamara Berkutzki, Anthony H. Futerman, Daniela Amann-Zalcenstein, Alfred H. Merrill, Elad L. Laviad, Oshrit Ben-David, Ester Feldmesser, Michal Levy, Shifra Ben-Dor, Ori Brenner, Svantje Braun, Shirley Horn-Saban, Hyejung Park, Racheli Erez-Roman
Publikováno v:
Journal of Biological Chemistry. 285:10911-10923
We have generated a mouse that cannot synthesize very long acyl chain (C22–C24) ceramides (Pewzner-Jung, Y., Park, H., Laviad, E. L., Silva, L. C., Lahiri, S., Stiban, J., Erez-Roman, R., Brugger, B., Sachsenheimer, T., Wieland, F. T., Prieto, M.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1da294dad9e1a84a8016947e8f4cdf0
https://doi.org/10.1074/jbc.m109.077610
https://doi.org/10.1074/jbc.m109.077610