Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ela Markovsky"'
Autor:
Ela Markovsky, Elisa de Stanchina, Susan A. Rotenberg, Aryeh Itzkowitz, Adriana Haimovitz-Friedman
Publikováno v:
Cellular Signalling. 52:74-82
Engineered overexpression of protein kinase Cα (PKCα) is known to phosphorylate Ser165 in α-tubulin resulting in stimulated microtubule dynamics and cell motility, and activation of an epithelial-mesenchymal transition (EMT) in non-transformed hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481740f26d6e6254be74b2a97b15d764
https://doi.org/10.1016/j.cellsig.2018.08.021
https://doi.org/10.1016/j.cellsig.2018.08.021
Autor:
Ryan Glass, Adriana Haimovitz-Friedman, Gary K. Schwartz, Simon N. Powell, Hongyan Li, Ela Markovsky, Feng Wang, Elisa de Stanchina
Publikováno v:
Oncotarget
Recent data in our laboratory indicate that engagement of host-derived microenvironmental elements impact tumor response to single high dose radiation therapy (SDRT). In these studies we showed that microvascular endothelial damage plays a critical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cc8a1cc03f64bd8dc859c440d0c098
https://doi.org/10.18632/oncotarget.24281
https://doi.org/10.18632/oncotarget.24281
Autor:
Rachel Shukrun, Revital Caspi, Iris Barshack, Orit Harari-Steinberg, Naomi Pode-Shakked, Ela Markovsky, Eilam Yeini, Benjamin Dekel, Anat Eldar-Boock, Dikla Ben-Shushan, Ronit Satchi-Fainaro, Einav Vax
Publikováno v:
Molecular Cancer Therapeutics. 16:2462-2472
Cancer stem cells (CSC) form a specific population within the tumor that has been shown to have self-renewal and differentiation properties, increased ability to migrate and form metastases, and increased resistance to chemotherapy. Consequently, eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2610f16eb4403a78c9a4b8486d600458
https://doi.org/10.1158/1535-7163.mct-17-0184
https://doi.org/10.1158/1535-7163.mct-17-0184
Autor:
Iris Barshack, Sarit Aviel-Ronen, Dikla Ben-Shushan, Ronit Satchi-Fainaro, Anat Eldar-Boock, Ela Markovsky, Hemda Baabur-Cohen, Eilam Yeini, Ariel Many, Evgeni Pisarevsky
Publikováno v:
Journal of Controlled Release. 249:162-172
Neural cell adhesion molecule (NCAM) expression is known to be associated with an aggressive biological behavior, increased metastatic capacity and expression of stem-cell markers in several tumor types. NCAM was also found to be expressed on tumor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5939bd0ea90aa64faca86ede4ab3eae
https://doi.org/10.1016/j.jconrel.2017.01.044
https://doi.org/10.1016/j.jconrel.2017.01.044
Autor:
Marcelo Calderón, Ela Markovsky, Stefanie Wedepohl, Evgeny Pisarevsky, Anat Eldar-Boock, Ronit Satchi-Fainaro, Harald Rune Tschiche, Laura Isabel Vossen
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 14(4)
Neural cell adhesion molecule (NCAM) is found to be a stem-cell marker in several tumor types and its overexpression is known to correlate with increased metastatic capacity. To combine extravasation- and ligand-dependent targeting to NCAM overexpres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3ac73dd9e522be715296cf0d1b48a6
https://pubmed.ncbi.nlm.nih.gov/29471169
https://pubmed.ncbi.nlm.nih.gov/29471169
Publikováno v:
Journal of Controlled Release. 187:145-157
Paclitaxel and doxorubicin are potent anticancer drugs used in the clinic as mono-therapies or in combination with other modalities to treat various neoplasms. However, both drugs suffer from side effects and poor pharmacokinetics. These two drugs ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb500534f3fd7974b974f438c41c0e3
https://doi.org/10.1016/j.jconrel.2014.05.025
https://doi.org/10.1016/j.jconrel.2014.05.025
Autor:
Adriana Haimovitz-Friedman, Johnn Humm, Joseph O. Deasy, Jedd Wolchok, Taha Merghoub, James Russell, Hongyan Li, Robert Samstein, Sadna Budhu, Simon Powell, Chloe Bodden, Ela Markovsky, Qing Chen
Publikováno v:
Cancer Research. 79:3735-3735
Purpose: To study tumor growth delay resulting from partial irradiation in preclinical mouse models. Methods and Materials: We investigated 67NR murine orthotopic breast tumors in both immunocompetent and nude mice. Treatment was delivered to 50% or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::825d65b42df31ce289bceaadcebbadae
https://doi.org/10.1158/1538-7445.am2019-3735
https://doi.org/10.1158/1538-7445.am2019-3735
Autor:
Galia Tiram, Hadas Gibori, Dikla Ben-Shushan, Ela Markovsky, Anna Scomparin, Ronit Satchi-Fainaro
Publikováno v:
Drug Delivery and Translational Research. 4:38-49
MicroRNAs (miRNAs) are small noncoding RNAs found to govern nearly every biological process. They frequently acquire a gain or a loss of function in cancer, hence playing a causative role in the development and progression of cancer. There are major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19291fa0723a273a5f91edf72f49c1b6
https://doi.org/10.1007/s13346-013-0160-0
https://doi.org/10.1007/s13346-013-0160-0
Autor:
Natalie Landa-Rouben, Galia Tiram, Laura Isabel Vossen, Marcelo Calderón, Hemda Baabur-Cohen, Ela Markovsky, Stefanie Wedepohl, Anat Eldar-Boock, Ronit Satchi-Fainaro, Jonathan Leor, Harald Rune Krüger, Eilam Yeini
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 257
Nowadays, combination therapy became a standard in oncology. In this study, we compare the activity of two polymeric carriers bearing a combination of the anticancer drugs paclitaxel (PTX) and doxorubicin (DOX), which differ mainly in their architect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf7681e89a8250493a9a076b488e168
https://pubmed.ncbi.nlm.nih.gov/27374630
https://pubmed.ncbi.nlm.nih.gov/27374630
Autor:
Hongyan Li, Robert M. Samstein, Adriana Haimovitz-Friedman, S.N. Powell, John L. Humm, Ela Markovsky, Joseph O. Deasy, James A. Russell
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 99:E616-E617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9a75fe6e08f241c63e7516e48fcc5d
https://doi.org/10.1016/j.ijrobp.2017.06.2086
https://doi.org/10.1016/j.ijrobp.2017.06.2086