Zobrazeno 1 - 10
of 52
pro vyhledávání: '"El-Sayed K. Assem"'
Publikováno v:
Biochemical Pharmacology. 62:1537-1544
We have studied the effect of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), two reactive oxygen species (ROS) on histamine release (HR) from RBL-2H3 cells, a rat mucosal-type mast cell line. Marked HR was elicited by antigen (DNP-HSA), calcium
Publikováno v:
Inflammation Research. 59:231-233
The effects of the endogenous antioxidant alpha-lipoic acid on guinea pig colon smooth muscle contraction (Gpcc) induced by hydrogen peroxide were examined. Having previously shown that the histone deacetylase (HDAC) benzamide inhibitor MGCD0103 inhi
Publikováno v:
Cell Calcium. 26:261-269
Using1999 Harcourt Publishers Ltdthe ratiometric Ca 2+ indicator, indo-1, the antigen-induced increase in intracellular Ca 2+ concentration ([Ca 2+ ] i ) was measured in individual RBL–2H3 cells which had been passively sensitized with monoclonal a
Autor:
El-Sayed K. Assem
Publikováno v:
Agents and Actions. 36:C206-C210
Anaphylactoid reactions (AR) to neuromuscular blockers (NMB), the most common cause of AR during general anaesthesia, are caused by the release of histamine and other mediators and can be detected by histamine from blood basophilsin vitro [1, 2]. The
Publikováno v:
Agents and Actions. 36:C275-C278
Inhibition of IgE-mediated histamine release from human basophils by cyclosporin-A (CsA) and 6 of its structural analogues (antiallergic, AA, effect) was investigated and compared with the inhibition of IL-2 secretion from EL4-NOB-1 cell lines, and p
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 59
The aim of this study was to investigate the ability of (a) antioxidants, some related to alpha-lipoic acid (LA), (b) histone deacetylase (HDAC) inhibitors, and (c) hybrid compounds possessing both alpha-lipoic acid-derived antioxidant properties and
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 58
Publikováno v:
Immunopharmacology. 20:31-43
In vitro the immonosuppressive drug cyclosporin A (CS-A) strongly inhibited histamine release from human basophils (HB) and the rat basophilic leukemia cell line (RBL) 2H3. It also inhibited leukotriene release from HB. In HB the IC50 values for inhi
Autor:
I. C. Ezeamuzie, El-Sayed K. Assem
Publikováno v:
Agents and Actions. 30:110-113
Cyclosporin A (CS-A) partly inhibited IgE-mediated histamine release from human lung tissue in vitro (chopped and collagenase-dispersed preparations). Inhibition started at concentrations within the clinical blood level of the drug, but the IC50 was
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 56