A biologically based model to quantitatively assess the role of the nuclear receptors liver X (LXR), and pregnane X (PXR) on chemically induced hepatic steatosis.

Autor: Bay C; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, United States., El-Masri HA; Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, United States. Electronic address: el-masri.hisham@epa.gov.

Publikováno v: Toxicology letters [Toxicol Lett] 2022 Apr 15; Vol. 359, pp. 46-54. Date of Electronic Publication: 2022 Feb 07.

Evaluation of a Physiologically Based Pharmacokinetic (PBPK) Model for Inorganic Arsenic Exposure Using Data from Two Diverse Human Populations.

Autor: El-Masri HA; National Health and Environmental Effects Research Laboratory, Office of Research and Development (ORD), U.S. Environmental Protection Agency (EPA), Durham, North Carolina, USA., Hong T; ICF International, Inc., Durham, North Carolina, USA., Henning C; ICF International, Inc., Durham, North Carolina, USA., Mendez W Jr; ICF International Inc., Fairfax, Virginia, USA., Hudgens EE; National Health and Environmental Effects Research Laboratory, Office of Research and Development (ORD), U.S. Environmental Protection Agency (EPA), Durham, North Carolina, USA., Thomas DJ; National Health and Environmental Effects Research Laboratory, Office of Research and Development (ORD), U.S. Environmental Protection Agency (EPA), Durham, North Carolina, USA., Lee JS; National Center for Environmental Assessment, ORD, EPA, Durham, North Carolina, USA.

Publikováno v: Environmental health perspectives [Environ Health Perspect] 2018 Jul 16; Vol. 126 (7), pp. 077004. Date of Electronic Publication: 2018 Jul 16 (Print Publication: 2018).

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