Tiron enhances the anti-cancer activity of doxorubicin in DMBA-induced breast cancer: Role of Notch signaling/apoptosis/autophagy/oxidative stress.

Autor: Abouelezz HM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. Electronic address: hadeer.abouelezz@mans.edu.eg., El-Kashef DH; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Abdеlaziz RR; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Nader MA; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2024 Nov; Vol. 193, pp. 114968. Date of Electronic Publication: 2024 Aug 28.

Suppression of NLRP3 inflammasome orchestrates the protective efficacy of tiron against isoprenaline-induced myocardial injury.

Autor: Abdelrahaman D; Department of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Habotta OA; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt., Taher ES; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan., El-Ashry ES; Department of Pharmacology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt., Ibrahim I; Department of Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt., Abdeen A; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt., Ibrahim AM; Department of Administration and Nursing Education, College of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.; Department of Family and Community Health Nursing, Faculty of Nursing, Port-Said University, Port Said, Egypt., Ibrahim RM; Department of Physiology, Faculty of Medicine, Benha University, Benha, Egypt., Anwer H; Department of Physiology, Faculty of Medicine, Benha University, Benha, Egypt., Mihaela O; Department of Biology, Faculty of Agriculture, University of Life Sciences'King Michael I' from Timisoara, Timisoara, Romania., Olga R; Department of Biology, Faculty of Agriculture, University of Life Sciences'King Michael I' from Timisoara, Timisoara, Romania., Alwutayed KM; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Al-Serwi RH; Department of Basic Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia., Sorour SM; Department of Pharmacology, Faculty of Medicine, Benha University, Benha, Egypt., El-Kashef DH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Aug 15; Vol. 15, pp. 1379908. Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).

Indole Diketopiperazine Alkaloids from the Marine Sediment-Derived Fungus Aspergillus chevalieri against Pancreatic Ductal Adenocarcinoma.

Autor: El-Kashef DH; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt., Obidake DD; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Schiedlauske K; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Deipenbrock A; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Scharf S; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Wang H; Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China., Naumann D; Department of Chemistry and Biochemistry, University of Cologne, 50939 Cologne, Germany., Friedrich D; Department of Chemistry and Biochemistry, University of Cologne, 50939 Cologne, Germany., Miljanovic S; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Haj Hassani Sohi T; Institute of Inorganic Chemistry and Structural Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Janiak C; Institute of Inorganic Chemistry and Structural Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Pfeffer K; Institute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Teusch N; Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.

Publikováno v: Marine drugs [Mar Drugs] 2023 Dec 20; Vol. 22 (1). Date of Electronic Publication: 2023 Dec 20.

Diacerein mitigates adenine-induced chronic kidney disease in rats: Focus on TLR4/MYD88/TRAF6/NF-κB pathway.

Autor: Samaha MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: msamaha@mans.edu.eg., Nour OA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Sewilam HM; Department of Histology, Faculty of Medicine, Helwan University, Cairo 11795, Egypt., El-Kashef DH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

Publikováno v: Life sciences [Life Sci] 2023 Oct 15; Vol. 331, pp. 122080. Date of Electronic Publication: 2023 Sep 09.

Epigallocatechin-3-gallate in combination with corticosteroids mitigates heat stress-induced acute kidney injury through modulating heat shock protein 70 and toll-like receptor 4-dependent pathways.

Autor: Shafeek F; Faculty of Pharmacy, Pharmacology and Toxicology Department, Mansoura University, Mansoura, Egypt., El-Kashef DH; Faculty of Pharmacy, Pharmacology and Toxicology Department, Mansoura University, Mansoura, Egypt., Abu-Elsaad N; Faculty of Pharmacy, Pharmacology and Toxicology Department, Mansoura University, Mansoura, Egypt., Ibrahim T; Faculty of Pharmacy, Pharmacology and Toxicology Department, Mansoura University, Mansoura, Egypt.

Publikováno v: Phytotherapy research : PTR [Phytother Res] 2023 Aug; Vol. 37 (8), pp. 3559-3571. Date of Electronic Publication: 2023 Apr 24.