AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs.

Autor: El Hadri, Khadija¹ khadija.zegouagh@upmc.fr, Denoyelle, Chantal², Ravaux, Lucas¹, Viollet, Benoit^3,4,5, Foretz, Marc^3,4,5, Friguet, Bertrand¹, Rouis, Mustapha¹, Raymondjean, Michel¹

Publikováno v: PLoS ONE. 7/10/2015, Vol. 10 Issue 7, p1-18. 18p.

Peroxisome Proliferator-activated Receptor γ Induces Apoptosis and Inhibits Autophagy of Human Monocyte-derived Macrophages via Induction of Cathepsin L

Autor: Mohamed-Naceur Slimane, Souliman Amrani, Thomas Simmet, Mustapha Rouis, Dler Faieeq Darweesh Mahmood, Tatiana Syrovets, El-Hadri Khadija, Nicolas Blondeau, Imene Jguirim-Souissi, Vimala Diderot

Publikováno v: Journal of Biological Chemistry. 286:28858-28866

Macrophages play a pivotal role in the pathophysiology of atherosclerosis. These cells express cathepsin L (CatL), a cysteine protease that has been implicated in atherogenesis and the associated arterial remodeling. In addition, macrophages highly e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c270868e64640c6ec5e0af6daa90f25a
https://doi.org/10.1074/jbc.m111.273292

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Thioredoxin-1 Promotes Anti-Inflammatory Macrophages of the M2 Phenotype and Antagonizes Atherosclerosis

Autor: El Hadri, Khadija, Faieeq, Dler, Mahmood, Darweesh, Couchie, Dominique, Jguirim-Souissi, Imene, Genze, Felicitas, Diderot, Vimala, Syrovets, Tatiana, Lunov, Oleg, Simmet, Thomas, Rouis, Mustapha

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2012, 32 (6), pp.1445+. ⟨10.1161/ATVBAHA.112.249334⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2012, 32 (6), pp.1445+. ⟨10.1161/ATVBAHA.112.249334⟩

Objective— Oxidative stress is believed to play a key role in cardiovascular disorders. Thioredoxin (Trx) is an oxidative stress-limiting protein with anti-inflammatory and antiapoptotic properties. Here, we analyzed whether Trx-1 might exert ather

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37d7bef8dadd77f946f6c4d677fd90e
https://hal.archives-ouvertes.fr/hal-01544074

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