Régulation de l'excitabilité musculaire par le canal potassique EGL-23 et la voie de signalisation LIN-12/Notch chez le nématode C. elegans

Autor: El Mouridi, Sonia

Les canaux potassiques à deux domaines pore (K2P) sont des régulateurs principaux de l’excitabilité cellulaire car ils jouent un rôle central dans l’établissement et le maintien du potentiel de repos des cellules animales. Malgré leur rôle

Externí odkaz: http://www.theses.fr/2018LYSE1199

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Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels

Autor: Ben Soussia, Ismail, El Mouridi, Sonia, Kang, Dawon, Leclercq-Blondel, Alice, Khoubza, Lamyaa, Tardy, Philippe, Zariohi, Nora, Gendrel, Marie, Lesage, Florian, Kim, Eun-Jin, Bichet, Delphine, Andrini, Olga, Boulin, Thomas

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.787. ⟨10.1038/s41467-019-08710-3⟩
Nature Communications, 2019, 10 (1), pp.787. ⟨10.1038/s41467-019-08710-3⟩

Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here, we reveal the conserved role played by a single amino acid position (TM2.6) located in the second tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::266c41ef1141a4166596211af053f14e
https://doaj.org/article/89358a70ca0b4f15867e6e9b7f65b48a

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Characterizing short germline-specific promoters with a range of expression levels in C. elegans .

Autor: Aljohani MD; King Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division (BESE), KAUST Environmental Epigenetics Program (KEEP), Thuwal, 23955-6900, Saudi Arabia., El Mouridi S; King Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division (BESE), KAUST Environmental Epigenetics Program (KEEP), Thuwal, 23955-6900, Saudi Arabia., Frøkjær-Jensen C; King Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division (BESE), KAUST Environmental Epigenetics Program (KEEP), Thuwal, 23955-6900, Saudi Arabia.

Publikováno v: MicroPublication biology [MicroPubl Biol] 2023 Jul 10; Vol. 2023. Date of Electronic Publication: 2023 Jul 10 (Print Publication: 2023).