Microwave-assisted synthesis of novel steroidal heterocyclic analogs as potent inhibitors of RANKL-induced osteoclastogenesis.

Autor: Elmasry GF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Ali RA; Hormones Department, National Research Centre, Medical Research and Clinical Studies Institute, Dokki, Egypt., El-Kady DS; Hormones Department, National Research Centre, Medical Research and Clinical Studies Institute, Dokki, Egypt., El-Moghazy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Elmegeed GA; Hormones Department, National Research Centre, Medical Research and Clinical Studies Institute, Dokki, Egypt., Tantawy MA; Hormones Department, National Research Centre, Medical Research and Clinical Studies Institute, Dokki, Egypt.; Stem Cells Lab Center of Excellence for Advanced Sciences, National Research Centre, Cairo, Dokki, Egypt.

Publikováno v: Drug development research [Drug Dev Res] 2023 Nov; Vol. 84 (7), pp. 1522-1536. Date of Electronic Publication: 2023 Aug 11.

Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks.

Autor: Abdelazeem AH; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt. Electronic address: ahmed.abdelazeem@pharm.bsu.edu.eg., Safi El-Din AG; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Abdel-Fattah MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Amin NH; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., El-Moghazy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: samirelmoghazy@gmail.com., El-Saadi MT; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt; Department of Medicinal Chemistry, Faculty of Pharmacy, Sinai University, Kantra, Egypt.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2020 Nov 01; Vol. 205, pp. 112662. Date of Electronic Publication: 2020 Jul 24.

Design, synthesis and docking studies of novel benzopyrone derivatives as anticonvulsants.

Autor: Abd-Allah WH; Pharmaceutical Chemistry Department, College of Pharmaceutical Science and Drug Manufacturing, Misr University for Science & Technology, P.O. 77, 6th of October City, Giza, Egypt. Electronic address: walaa.abdalla@must.edu.eg., Osman EEA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt., Anwar MA; Pharmaceutical Chemistry Department, College of Pharmaceutical Science and Drug Manufacturing, Misr University for Science & Technology, P.O. 77, 6th of October City, Giza, Egypt., Attia HN; Medicinal and Pharmaceutical Chemistry Department (Pharmacology Group) Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., El Moghazy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2020 May; Vol. 98, pp. 103738. Date of Electronic Publication: 2020 Mar 10.

Screening and optimization of samarium-assisted complexation for the determination of norfloxacin, levofloxacin and lomefloxacin in their corresponding dosage forms employing spectrofluorimetry.

Autor: El-Hamshary MS; Department of Chemistry and Earth Sciences, College of Arts and Sciences, Qatar University, Doha 2713, Qatar. Electronic address: melhamshary@qu.edu.qa., Fouad MA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Hanafi RS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Egypt., Al-Easa HS; Department of Chemistry and Earth Sciences, College of Arts and Sciences, Qatar University, Doha 2713, Qatar., El-Moghazy SM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

Publikováno v: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2019 Jan 05; Vol. 206, pp. 578-587. Date of Electronic Publication: 2018 Aug 29.

Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers.

Autor: Nowar RM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Heliopolis University for Sustainable Development, 11777 Cairo, Egypt., A Osman EE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt., Abou-Seri SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt., El Moghazy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt., Abou El Ella DA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, 11566 Cairo, Egypt.

Publikováno v: Future medicinal chemistry [Future Med Chem] 2018 May 01; Vol. 10 (10), pp. 1191-1205. Date of Electronic Publication: 2018 May 11.