Parkin coregulates glutathione metabolism in adult mammalian brain.

Autor: El Kodsi, Daniel N.^1,2 (AUTHOR), Tokarew, Jacqueline M.^1,2 (AUTHOR), Sengupta, Rajib^3,4 (AUTHOR), Lengacher, Nathalie A.^1,2 (AUTHOR), Chatterji, Ajanta^1,2 (AUTHOR), Nguyen, Angela P.^1,5 (AUTHOR), Boston, Heather¹ (AUTHOR), Jiang, Qiubo¹ (AUTHOR), Palmberg, Carina³ (AUTHOR), Pileggi, Chantal⁶ (AUTHOR), Holterman, Chet E.⁷ (AUTHOR), Shutinoski, Bojan¹ (AUTHOR), Li, Juan¹ (AUTHOR), Fehr, Travis K.^1,2 (AUTHOR), LaVoie, Matthew J.⁸ (AUTHOR), Ratan, Rajiv R.⁹ (AUTHOR), Shaw, Gary S.¹⁰ (AUTHOR), Takanashi, Masashi¹¹ (AUTHOR), Hattori, Nobutaka¹¹ (AUTHOR), Kennedy, Christopher R.⁷ (AUTHOR)

Publikováno v: Acta Neuropathologica Communications. 1/23/2023, Vol. 11 Issue 1, p1-21. 21p.

Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data.

Autor: Simmons SK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Adiconis X; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Haywood N; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Parker J; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT 06510, USA., Lin Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT 06510, USA., Liao Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Tuncali I; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Al'Khafaji AM; Broad Clinical Labs, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Shin A; Broad Clinical Labs, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Jagadeesh K; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Gosik K; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Gatzen M; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Smith JT; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., El Kodsi DN; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Kuras Y; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Baecher-Allan C; Dept. of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Serrano GE; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Banner Sun Health Research Institute, Sun City, AZ 85351, USA., Beach TG; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Banner Sun Health Research Institute, Sun City, AZ 85351, USA., Garimella K; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Present address: Genentech, South San Francisco, CA 94080, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Present address: Genentech, South San Francisco, CA 94080, USA., Dong X; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT 06510, USA., Scherzer CR; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT 06510, USA., Levin JZ; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 16. Date of Electronic Publication: 2024 Aug 16.