Výsledky vyhledávání - "El Hakim Ramadan A"

Akademický článek

Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy

Autor: Abd El hakim Ramadan, Mahmoud M.A. Elsayed, Amani Elsayed, Marwa A. Fouad, Mohamed S. Mohamed, Sangmin Lee, Reda A. Mahmoud, Shereen A. Sabry, Mohammed M. Ghoneim, Ahmed H.E. Hassan, Reham A. Abd Elkarim, Amany Belal, Ahmed A. El-Shenawy

Publikováno v: International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100232- (2024)

Diabetes mellitus (DM) is the most prevalent cause of diabetic retinopathy (DRP). DRP has been recognized for a long time as a microvascular disease. Many drugs were used to treat DRP, including vildagliptin (VLD). In addition to its hypoglycemic eff

Externí odkaz: https://doaj.org/article/90e9c3cc813e48a999c5c8078831a32b

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Akademický článek

Anti-Tumor Activity of Orally Administered Gefitinib-Loaded Nanosized Cubosomes against Colon Cancer

Autor: Ahmed A. El-Shenawy, Mahmoud M. A. Elsayed, Gamal M. K. Atwa, Mohammed A. S. Abourehab, Mohamed S. Mohamed, Mohammed M. Ghoneim, Reda A. Mahmoud, Shereen A. Sabry, Walid Anwar, Mohamed El-Sherbiny, Yasser A. Hassan, Amany Belal, Abd El hakim Ramadan

Publikováno v: Pharmaceutics, Vol 15, Iss 2, p 680 (2023)

Gefitinib (GFT) is a tyrosine kinase inhibitor drug used as a first-line treatment for patients with advanced or metastatic non-small cell lung, colon, and breast cancer. GFT exhibits low solubility and hence low oral bioavailability, which restricts

Externí odkaz: https://doaj.org/article/edf3bae5918948f491e4770af7add1d3

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Akademický článek

Tailoring of Rosuvastatin Calcium and Atenolol Bilayer Tablets for the Management of Hyperlipidemia Associated with Hypertension: A Preclinical Study

Autor: Mahmoud M. A. Elsayed, Moustafa O. Aboelez, Mohamed S. Mohamed, Reda A. Mahmoud, Ahmed A. El-Shenawy, Essam A. Mahmoud, Ahmed A. Al-Karmalawy, Eman Y. Santali, Sameer Alshehri, Mahmoud Elkot Mostafa Elsadek, Mohamed A. El Hamd, Abd El hakim Ramadan

Publikováno v: Pharmaceutics, Vol 14, Iss 8, p 1629 (2022)

Hyperlipidemia is still the leading cause of heart disease in patients with hypertension. The purpose of this study is to make rosuvastatin calcium (ROS) and atenolol (AT) bilayer tablets to treat coexisting dyslipidemia and hypertension with a singl

Externí odkaz: https://doaj.org/article/ed3d840321ea41b296a642d297400de6

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Akademický článek

Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma

Autor: Mahmoud M. A. Elsayed, Tarek M. Okda, Gamal M. K. Atwa, Gamal A. Omran, Atef E. Abd Elbaky, Abd El hakim Ramadan

Publikováno v: Pharmaceutics, Vol 13, Iss 5, p 648 (2021)

Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant anti-tumor activity in many cancer cells, including hepatocellular carcinoma (HCC). The most re

Externí odkaz: https://doaj.org/article/1c2a726a5367469da032672fa0d79543

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Response Surface Methodology as a Useful Tool for Development and Optimization of Sustained Release Ketorolac Tromethamine Niosomal Organogels

Autor: Amal K. Hussein, Abd El hakim Ramadan, Saleh Abd El Rasoul, Mahmoud M. A. Elsayed

Publikováno v: Journal of Pharmaceutical Innovation. 15:664-677

Niosomes as vesicular frameworks are novel methods of delivering a drug in a sustained manner to enhance its bioavailability and get therapeutic effect over a longer period time. This study conclusively demonstrates the preparation, characterization,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fa102173d71f21dafc6287c6ca49e97
https://doi.org/10.1007/s12247-019-09421-4

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Formulation, characterization, and evaluation of the anti-tumor activity of nanosized galangin loaded niosomes on chemically induced hepatocellular carcinoma in rats

Autor: Abd El hakim Ramadan, Shereen A. Sabry, Tarek Okda, Azza A. Hasan, Mahmoud Abd elghany

Publikováno v: Journal of Drug Delivery Science and Technology. 61:102163

Galangin (GAL) is a flavonoid with anti-tumor activity. However, its poor solubility results in low bioavailability thus hindering its clinical application. To overcome this challenge, we have prepared niosomal vesicles by reverse-phase evaporation t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dff4c1899abb71e5fdda4e0d2a2de5e7
https://doi.org/10.1016/j.jddst.2020.102163

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