Zobrazeno 1 - 2
of 2
pro vyhledávání: '"El Bahi Takkouche Souilamas"'
Autor:
Miguel-Ángel García-González, Jose-Domingo Moure-Gonzalez, María-Esther San-José-Capilla, Tania Liñares-Mata, Ana Faraldo-García, Montserrat Nogueira, Pablo Martin-Lancharro, Francisco-Javier González-Barcala, Francisco-Javier Salgado-Castro, Pilar Arias, Carmen Diego-Roza, Juan-José Nieto-Fontarigo, El-Bahi Takkouche-Souilamas, Luis Valdés-Cuadrado, José-Martín Carreira-Villamor
Publikováno v:
Allergy and immunology.
In 2003, FDA approved Omalizumab for the treatment of severe allergic asthma. This mAb recognizes IgE and blocks its binding to basophils and mast cells, attenuating FceRI signalling. Nevertheless, its effect on T helper (Th) subsets like regulatory
Autor:
El Bahi Takkouche Souilamas, Juan José Nieto Fontarigo, Montserrat Nogueira Álvarez, Ana Faraldo Garcia, Francisco Javier Salgado Castro, Luis Valdés Cuadrado, Maria Esther San Jose Capilla, María Jesús Cruz, Francisco Javier González Barcala, Pilar Arias Crespo, Jose Martin Carreira Villamor, Miguel Angel Garcia Gonzalez
Publikováno v:
Allergy and immunology.
The role of effector TH cells (Teff; CD25 low CD127 high ) like TH17 lymphocytes in asthma depends on their interplay with regulatory T cells (Treg; CD25 high CD127 low ), which display low levels of CD26 (TH17>>TH1>TH2>>Treg) but high of LRRC32. The