Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Elżbieta Speina"'
Autor:
Daniel Paprocki, Maria Winiewska-Szajewska, Elżbieta Speina, Róża Kucharczyk, Jarosław Poznański
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract 4,5,6,7-Tetrabromo-1H-benzotriazole is widely used as the reference ATP-competitive inhibitor of protein kinase CK2. Herein, we study its new analogs: 5,6-diiodo- and 5,6-diiodo-4,7-dibromo-1H-benzotriazole. We used biophysical (MST, ITC) an
Externí odkaz:
https://doaj.org/article/f45616c690f94f309e3445b6e29865d9
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 291 (2023)
Benzodiazepines that consist of one α- and one β-amino acid residues linked together in a seven-membered heterocyclic ring could be treated as small, rigid, cyclic dipeptides capable of exhibiting a wide range of biological activities. During our r
Externí odkaz:
https://doaj.org/article/b6751b143cef4e0fa0b6d4e69362d70f
Autor:
Maria Winiewska-Szajewska, Agnieszka Monika Maciejewska, Elżbieta Speina, Jarosław Poznański, Daniel Paprocki
Publikováno v:
Molecules, Vol 26, Iss 11, p 3163 (2021)
Protein kinase CK2 is a highly pleiotropic protein kinase capable of phosphorylating hundreds of protein substrates. It is involved in numerous cellular functions, including cell viability, apoptosis, cell proliferation and survival, angiogenesis, or
Externí odkaz:
https://doaj.org/article/be95652a1222405da31188fc4c7f7675
Autor:
Adam Mieczkowski, Elżbieta Speina, Damian Trzybiński, Maria Winiewska-Szajewska, Patrycja Wińska, Ewelina M. Borsuk, Małgorzata Podsiadła-Białoskórska, Tomasz Przygodzki, Krzysztof Drabikowski, Lidia Stanczyk, Igor Zhukov, Cezary Watala, Krzysztof Woźniak
Publikováno v:
Molecules, Vol 26, Iss 4, p 794 (2021)
Phosphodiesterase 5 (PDE5) is one of the most extensively studied phosphodiesterases that is highly specific for cyclic-GMP hydrolysis. PDE5 became a target for drug development based on its efficacy for treatment of erectile dysfunction. In the pres
Externí odkaz:
https://doaj.org/article/529700a96a6149368266ec407e248c4b
Autor:
Elżbieta Speina, Jarosław Poznański, Agnieszka M. Maciejewska, Maria Winiewska-Szajewska, Daniel Paprocki
Publikováno v:
Molecules, Vol 26, Iss 3163, p 3163 (2021)
Molecules
Volume 26
Issue 11
National Information Processing Institute
Molecules
Volume 26
Issue 11
National Information Processing Institute
Protein kinase CK2 is a highly pleiotropic protein kinase capable of phosphorylating hundreds of protein substrates. It is involved in numerous cellular functions, including cell viability, apoptosis, cell proliferation and survival, angiogenesis, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66274e2a6bdb16ab12391db26ce9f462
https://www.mdpi.com/1420-3049/26/11/3163
https://www.mdpi.com/1420-3049/26/11/3163
Autor:
Patrycja Wińska, Tomasz Przygodzki, Elżbieta Speina, Ewelina M Borsuk, Krzysztof Woźniak, Damian Trzybiński, Malgorzata Podsiadla-Bialoskorska, Adam Mieczkowski, Igor Zhukov, Lidia Stanczyk, Maria Winiewska-Szajewska, Krzysztof Drabikowski, Cezary Watala
Publikováno v:
Molecules
Volume 26
Issue 4
Molecules, Vol 26, Iss 794, p 794 (2021)
Volume 26
Issue 4
Molecules, Vol 26, Iss 794, p 794 (2021)
Phosphodiesterase 5 (PDE5) is one of the most extensively studied phosphodiesterases that is highly specific for cyclic-GMP hydrolysis. PDE5 became a target for drug development based on its efficacy for treatment of erectile dysfunction. In the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53467b60155a80b533c40414cbda7734
Autor:
Elżbieta Speina, Somayeh Shahmoradi Ghahe, Agnieszka Tudek, Konrad Kosicki, Milena Bazlekowa-Karaban, Daria Zdżalik-Bielecka, Ewelina M. Borsuk, Jolanta Czerwińska
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 852
Professor Barbara Tudek received the Frits Sobels Award in 2019 from the European Environmental Mutagenesis and Genomics Society (EEMGS). This article presents her outstanding character and most important lines of research. The focus of her studies c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b999aafea814d4a81679b788daf7a95c
https://pubmed.ncbi.nlm.nih.gov/32265045
https://pubmed.ncbi.nlm.nih.gov/32265045
Autor:
Aditi U. Gurkar, Małgorzata Nowak, Jolanta Czerwińska, Dorota Dziuban-Lech, Elżbieta Speina, Jarosław M. Cieśla, Barbara Tudek, Anna Barańczyk-Kuźma, Konrad Kosicki, Daria Kołata, Ryszard Olinski, Hillary L. Shane, Lora H. Rigatti, Patrycja Wojtczak, Małgorzata Bednarek, Beata Gajewska, Matthew J. Yousefzadeh, Ewelina Zarakowska, Daniel Gackowski, Siobhán Q. Gregg, Andria Rasile Robinson, Sara J. McGowan, Laura J. Niedernhofer
Publikováno v:
Free Radical Biology and Medicine. 124:79-96
Lipid peroxidation (LPO) products are relatively stable and abundant metabolites, which accumulate in tissues of mammals with aging, being able to modify all cellular nucleophiles, creating protein and DNA adducts including crosslinks. Here, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4531404d6bb1263216926690c73cf8f2
https://doi.org/10.1016/j.freeradbiomed.2018.05.088
https://doi.org/10.1016/j.freeradbiomed.2018.05.088
Autor:
Agata Ciuba, Maria Wojewódzka, Elżbieta Speina, Konrad Kosicki, Roksana Iwanicka-Nowicka, Anna Fogtman, Marcin Kruszewski, Barbara Tudek, Marta Koblowska, Somayeh Shahmoradi Ghahe, Bartosz Majchrzak
Publikováno v:
DNA Repair. 104:103136
Photodynamic therapy (PDT) is a clinically approved cancer therapy of low invasiveness. The therapeutic procedure involves administering a photosensitizing drug (PS), which is then activated with monochromatic light of a specific wavelength. The phot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0c3630368615654f3d38d7644b9ff2
https://doi.org/10.1016/j.dnarep.2021.103136
https://doi.org/10.1016/j.dnarep.2021.103136
Autor:
Anna Fabisiewicz, Agnieszka Tudek, Konrad Kosicki, Elżbieta Speina, Daria Zdżalik-Bielecka, Barbara Tudek
Publikováno v:
Tudek, B, Zdżalik-Bielecka, D, Tudek, A, Kosicki, K, Fabisiewicz, A & Speina, E 2017, ' Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes ', Free Radical Biology & Medicine, vol. 107, pp. 77-89 . https://doi.org/10.1016/j.freeradbiomed.2016.11.043
Exocyclic adducts to DNA bases are formed as a consequence of exposure to certain environmental carcinogens as well as inflammation and lipid peroxidation (LPO). Complex family of LPO products gives rise to a variety of DNA adducts, which can be grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0f31d4e70cf5a94fd723e6c3fa9728
https://pure.au.dk/portal/da/publications/lipid-peroxidation-in-face-of-dna-damage-dna-repair-and-other-cellular-processes(d049f0fc-cd67-410b-af99-669bfec06d5d).html
https://pure.au.dk/portal/da/publications/lipid-peroxidation-in-face-of-dna-damage-dna-repair-and-other-cellular-processes(d049f0fc-cd67-410b-af99-669bfec06d5d).html
