Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elżbieta Hiszczyńska-Sawicka"'
Publikováno v:
Veterinary Parasitology. 206:146-152
Toxoplasmosis, caused by Toxoplasma gondii, is the major parasitic disease affecting sheep. Infection not only results in significant reproductive losses in these animals, but has public health implications since consumption of infected meat can faci
Autor:
Roy Bickerstaffe, Hong Li, Gabriela Olędzka, M. Stankiewicz, Józef Kur, Elżbieta Hiszczyńska-Sawicka, Richard Sedcole, Lucyna Holec-Gąsior, Janet Boyu Xu
Publikováno v:
Veterinary Parasitology. 177:281-289
The dense granule proteins of Toxoplasma gondii are investigated as possible vaccine candidates against the parasite. The aim of this research was to evaluate the immune responses of sheep injected twice, intramuscularly, with DNA plasmids encoding T
Publikováno v:
Parasitology. 141(11)
SUMMARYToxoplasma gondii is a cosmopolitan protozoan parasite that infects a wide range of mammal and bird species. Common infection leads to high economic (e.g. abortions in sheep) and human (e.g. congenital toxoplasmosis or neurotoxoplasmosis in hu
Publikováno v:
Plasmid. 38:174-179
Four isogenic strains (himAhimD double mutant, himA and himD single mutants, and their wild type counterpart) harboring orip15A plasmid (pACYC184 or pACYC184Amp or pACYC177) show different copy numbers of that plasmid in the early stationary phase of
Autor:
E. Petersen, M. Stankiewicz, I. Andrzejewska, Henrik Vedel Nielsen, Przemysław Myjak, Elżbieta Hiszczyńska-Sawicka, Halina Pietkiewicz, Józef Kur
Publikováno v:
Journal of Clinical Microbiology. 42:1779-1781
Toxoplasma gondii SAG1, GRA1, and GRA7 recombinant antigens may be regarded as tools for the detection of T. gondii immunoglobulin G antibodies in persons with chronic and acute toxoplasmosis. GRA7 is more correlated with acute toxoplasmosis. A combi
Publikováno v:
Acta Biochimica Polonica. 42:103-108
The integration host factor (IHF) is a sequence-specific, histone-like, multi-functional DNA-binding and -bending protein of Escherichia coli. Characterization and functional analysis of this protein has been carried out mainly in bacteriophage lambd
Autor:
Roy Bickerstaffe, M. Stankiewicz, Elżbieta Hiszczyńska-Sawicka, H. Li, J. B. Xu, M. Akhtar, Lucyna Holec-Gąsior, Józef Kur
Publikováno v:
Polish Journal of Veterinary Sciences. 15
Toxoplasma gondii is a parasite that has been extensively studied due to its medical and veterinary importance in terminating pregnancies. Consequently, a satisfactory vaccine is required to control its adverse effects on pregnant animals. The micron
Autor:
Elżbieta Hiszczyńska-Sawicka, Lucyna Holec-Gąsior, Józef Kur, Janet Boyu Xu, Richard Sedcole, Hong Li, Roy Bickerstaffe, M. Stankiewicz
Publikováno v:
Veterinary parasitology. 183(1-2)
CD154 is a cell surface molecule expressed by activated T cells. CD40 and CD154 interaction is critically important in regulating humoral and cell-mediated immune responses. In this study we have investigated whether a DNA vaccine encoding rhoptry pr
Publikováno v:
Expert review of vaccines. 8(6)
Toxoplasmosis, caused by an intracellular protozoan parasite, Toxoplasma gondii, is widespread throughout the world. The disease is of major medical and veterinary importance, being a cause of congenital disease and abortion in humans and domestic an
Autor:
Józef Kur, Janet Boyu Xu, Hong Li, Roy Bickerstaffe, M. Stankiewicz, Gabriela Olędzka, Elżbieta Hiszczyńska-Sawicka
Publikováno v:
Experimental parasitology. 124(4)
Immunization with plasmid DNA, a relatively novel technique, is a promising vaccination technique. To improve the immune response by DNA vaccination various methods have been used, such as chemical adjuvants or immunomodulatory molecules formulated i