Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Elísabet Alcocer-Gómez"'
Autor:
Alvaro González‐Dominguez, Raúl Montañez, Beatriz Castejón‐Vega, Jéssica Nuñez‐Vasco, Débora Lendines‐Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro‐Pando, Elísabet Alcocer‐Gómez, Mario D Cordero
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-7 (2021)
Abstract Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS
Externí odkaz:
https://doaj.org/article/741ada3b7d4b430aadbd36423e7df82b
Autor:
Beatriz Castejón-Vega, Alejandro Rubio, Antonio J. Pérez-Pulido, José L. Quiles, Jon D. Lane, Beatriz Fernández-Domínguez, María Begoña Cachón-González, Carmen Martín-Ruiz, Alberto Sanz, Timothy M. Cox, Elísabet Alcocer-Gómez, Mario D. Cordero
Publikováno v:
Cells, Vol 10, Iss 11, p 3122 (2021)
Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA) l
Externí odkaz:
https://doaj.org/article/f52039e69fcc4dfe90d6e42e02924715
Autor:
Mario D Cordero, Francisco Javier Cano-García, Elísabet Alcocer-Gómez, Manuel De Miguel, José Antonio Sánchez-Alcázar
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35677 (2012)
BackgroundFibromyalgia (FM) is a chronic pain syndrome with unknown etiology and a wide spectrum of symptoms such as allodynia, debilitating fatigue, joint stiffness and migraine. Recent studies have shown some evidences demonstrating that oxidative
Externí odkaz:
https://doaj.org/article/74abe3b1cd824cb4ad578aeee8d22fff
Autor:
Mario D Cordero, Elísabet Alcocer-Gómez, Francisco J Cano-García, Manuel De Miguel, Angel M Carrión, Plácido Navas, José A Sánchez Alcázar
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26915 (2011)
BACKGROUND: We examined lipid peroxidation (LPO) in blood mononuclear cells (BMCs) and plasma, as a marker of oxidative damage, and its association to clinical symptoms in Fibromyalgia (FM) patients. METHODS: We conducted a case-control and correlati
Externí odkaz:
https://doaj.org/article/7351420581f44e7aa1dcedcee32182c9
Autor:
Beatriz Castejón-Vega, Diego Cañadas-Lozano, Mario D. Cordero, Jesús Ruiz-Cabello, José M. Navarro-Pando, Pedro Bullón, Bernhard Ryffel, Elísabet Alcocer-Gómez, Fabiola Marín-Aguilar
Publikováno v:
GeroScience
Aging is the major risk factor for many metabolic chronic diseases. Several metabolic pathways suffer a progressive impairment during aging including body composition and insulin resistance which are associated to autophagy dysfunction and increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbca76764574cee4319b47027bc64b5
https://doi.org/10.1007/s11357-019-00151-6
https://doi.org/10.1007/s11357-019-00151-6
Autor:
Mario D. Cordero, José L. Quiles, Maria Begoña Cachón-González, Alberto Sanz, Alejandro Rubio, Pedro Bullón, Carmen Martin-Ruiz, Jon D. Lane, Beatriz Castejón-Vega, Antonio J. Pérez-Pulido, Beatriz Fernández Domínguez, Timothy M. Cox, Débora Lendines-Cordero, Elísabet Alcocer-Gómez
Tay-Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause fatal and progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687aabc13355f77b5beabb03f30417b0
https://doi.org/10.1101/2021.05.28.446132
https://doi.org/10.1101/2021.05.28.446132
Autor:
Elísabet Alcocer-Gómez, Bernhard Ryffel, Alberto Sanz, Gabriel Mbalaviele, Mario D. Cordero, Elena Navarro-Villarán, María Mundi-Roldan, Jordi Muntané, Pedro Bullón, Chun Wang, Hal M. Hoffman, Antonio J. Pérez-Pulido, Mónica Condés-Hervás, Beatriz Castejón-Vega, José M. Navarro-Pando
Publikováno v:
Science Advances
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2021 The Authors.
Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. Age-dependent increased expression of NLR
Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. Age-dependent increased expression of NLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b45228fa7685c5038f297ed797c9b8
Autor:
José M. Navarro-Pando, Débora Lendines-Cordero, Mario D. Cordero, Raúl Montañez, Gabriel Mbalaviele, Alvaro González-Dominguez, Jéssica Nuñez-Vasco, Elísabet Alcocer-Gómez, Beatriz Castejón-Vega, Chun Wang
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b979333b420f912cb3d0a1d04d41ad
Autor:
Alejandro Rubio, José L. Quiles, Antonio J. Pérez-Pulido, Beatriz Fernández-Domínguez, Beatriz Castejón-Vega, Elísabet Alcocer-Gómez, Jon D. Lane, Carmen Martin-Ruiz, Maria Begoña Cachón-González, Alberto Sanz, Mario D. Cordero, Timothy M. Cox
Publikováno v:
Cells
Volume 10
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digibug. Repositorio Institucional de la Universidad de Granada
Castejon Vega, B, Rubio, A, Perez-Pulido, A, Quiles, J, Lane, J D, Fernandez-Dominguez, B, Cachon-Gonzales, M, Martin-Ruiz, C, Sanz, A, Cox, T, Alcocer-Gomez, E & Cordero, M 2021, ' L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation ', Cells, vol. 10, no. 11, 3122 . https://doi.org/10.3390/cells10113122
Cells, Vol 10, Iss 3122, p 3122 (2021)
Volume 10
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digibug. Repositorio Institucional de la Universidad de Granada
Castejon Vega, B, Rubio, A, Perez-Pulido, A, Quiles, J, Lane, J D, Fernandez-Dominguez, B, Cachon-Gonzales, M, Martin-Ruiz, C, Sanz, A, Cox, T, Alcocer-Gomez, E & Cordero, M 2021, ' L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation ', Cells, vol. 10, no. 11, 3122 . https://doi.org/10.3390/cells10113122
Cells, Vol 10, Iss 3122, p 3122 (2021)
Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aa2a1f3f1a3fa6642540dc57aa082c
http://hdl.handle.net/10481/71460
http://hdl.handle.net/10481/71460
Autor:
Mario D. Cordero, José M. Navarro-Pando, Jéssica Nuñez-Vasco, Beatriz Castejón-Vega, Débora Lendines-Cordero, Elísabet Alcocer-Gómez
Inflammation is a hallmark of aging and accelerated aging syndromes. In this context, inflammation has been associated to the pathophysiology of Hutchinson–Gilford progeria syndrome (HGPS). In this study, we report that progeroid skin fibroblasts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22d62340a5db08a4e6175e389eda452f
https://doi.org/10.1101/2020.09.09.288290
https://doi.org/10.1101/2020.09.09.288290