Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ekta Makhija"'
Autor:
Ekta Makhija, Yang Zheng, Jiahao Wang, Han Ren Leong, Rashidah Binte Othman, Ee Xien Ng, Eng Hin Lee, Lisa Tucker Kellogg, Yie Hou Lee, Hanry Yu, Zhiyong Poon, Krystyn J Van Vliet
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0297769 (2024)
Mesenchymal stromal cells (MSCs) are promising therapeutic agents for cartilage regeneration, including the potential of cells to promote chondrogenesis in vivo. However, process development and regulatory approval of MSCs as cell therapy products be
Externí odkaz:
https://doaj.org/article/fdd2b05d427b4cd58e59d81e91169f02
Autor:
Ekta Makhija, Anna Jagielska, Lena Zhu, Alexander C. Bost, William Ong, Sing Y. Chew, G. V. Shivashankar, Krystyn J. Van Vliet
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Mechanical and physical stimuli including material stiffness and topography or applied mechanical strain have been demonstrated to modulate differentiation of glial progenitor and neural stem cells. Recent studies probing such mechanotransduction in
Externí odkaz:
https://doaj.org/article/397c7a15fae64f6289e5b3896e6511a8
Autor:
Krystyn J. Van Vliet, Anna Jagielska, Alexis L. Lowe, Ekta Makhija, Liliana Wroblewska, Jochen Guck, Robin J. M. Franklin, G. V. Shivashankar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Differentiation of oligodendrocyte progenitor cells (OPC) to oligodendrocytes and subsequent axon myelination are critical steps in vertebrate central nervous system (CNS) development and regeneration. Growing evidence supports the significance of me
Externí odkaz:
https://doaj.org/article/ee7455fb847c4337ba68b30762070267
Autor:
Ekta Makhija, Yang Zheng, Jiahao Wang, Han Ren Leong, Rashidah Binte Othman, Ee Xien Ng, Eng Hin Lee, Lisa Tucker Kellogg, Yie Hou Lee, Hanry Yu, Zhiyong Poon, Krystyn Joy Van Vliet
A critical initial stage of skeletal morphogenesis involves formation of highly compact aggregates of mesenchymal cells, known as mesenchymal condensations, appearing as regularly-spaced pattern of spots. Conventional computational models to understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a139907af8b88d02cfaafdf58d58ec2
https://doi.org/10.1101/2022.05.30.493944
https://doi.org/10.1101/2022.05.30.493944
Publikováno v:
Neuroscience letters. 717
Oligodendrocytes (OL) are a subset of glial cells in the central nervous system (CNS) comprising the brain and spinal cord. The CNS environment is defined by complex biochemical and biophysical cues during development and response to injury or diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a296779a1075f19d149ec135b02a57
https://pubmed.ncbi.nlm.nih.gov/31838017
https://pubmed.ncbi.nlm.nih.gov/31838017
Publikováno v:
Journal of Visualized Experiments.
Extracellular mechanical strain is known to elicit cell phenotypic responses and has physiological relevance in several tissue systems. To capture the effect of applied extracellular tensile strain on cell populations in vitro via biochemical assays,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4965dddf511dcedbf86ab08e90a224
https://doi.org/10.3791/59474-v
https://doi.org/10.3791/59474-v
Autor:
Aneesh Srivastava, Gaurav Pandey, Ekta Makhija, Swasti Tiwari, Anil N. Gaikwad, Anil Mandhani, Carolyn A. Ecelbarger, Kripa Shankar
Publikováno v:
Journal of Cellular Biochemistry. 118:276-285
Reduced insulin receptor protein levels have been reported in the kidney cortex from diabetic humans and animals. We recently reported that, targeted deletion of insulin receptor (IR) from proximal tubules (PT) resulted in hyperglycemia in non-obese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dde99e8332ca08f53a6efaaabb4950f2
https://doi.org/10.1002/jcb.25632
https://doi.org/10.1002/jcb.25632
Physical boundary conditions of the cell define its cytoskeletal organization and thus regulate the force balance on the nucleus. The boundary can be very precisely engineered by plating cells on micropatterned substrate of various geometries. Such m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::219e69116dd9b60799f02dd608d4666f
https://doi.org/10.1016/b978-0-12-812952-4.00002-7
https://doi.org/10.1016/b978-0-12-812952-4.00002-7
Autor:
Madhawi Alanazi, Martha B. Alvarez-Elizondo, Kristi S. Anseth, Salma Ayoub, Akshay Badakere, Emma J. Blain, Rachel M. Buchanan, Alexander W. Caulk, Yunfeng Chen, Nikhil S. Choudhari, Vivek P. Dave, Eimear B. Dolan, Giovanni Ferrari, Sophie J. Gilbert, Jason P. Gleghorn, Geoffrey C. Gurtner, Jay D. Humphrey, Doorgesh Sharma Jokhun, Lining A. Ju, Alex Khang, Megan L. Killian, Abhishek Kumar, Sun Hyung Kwon, Chung-Hao Lee, Hui Li, Zhenhai Li, Ekta Makhija, Laoise M. McNamara, Ashik Mohamed, Ashraf M. Mohieldin, Derek Nankivil, Andromeda M. Nauli, Surya M. Nauli, Jagannath Padmanabhan, Amanda J. Page, Sunil Punjabi, A.V. Radhakrishnan, Bruno V. Rego, Ashutosh Richhariya, Rebecca A. Rolfe, Rakefet Rozen, Michael S. Sacks, Virender S. Sangwan, G.V. Shivashankar, George Tellides, Bhavani P. Thampatty, William J. Tyler, Stefaan W. Verbruggen, James H.-C. Wang, Daphne Weihs, Cheng Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1703888e82907ec2b968b42dde5ec229
https://doi.org/10.1016/b978-0-12-812952-4.09991-8
https://doi.org/10.1016/b978-0-12-812952-4.09991-8
Publikováno v:
Biochemical and Biophysical Research Communications. 461:372-377
Cells sense physical cues at the level of focal adhesions and transduce them to the nucleus by biochemical and mechanical pathways. While the molecular intermediates in the mechanical links have been well studied, their dynamic coupling is poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd98aeb73450d847686f8e0b6f300668
https://doi.org/10.1016/j.bbrc.2015.04.041
https://doi.org/10.1016/j.bbrc.2015.04.041